Zavedos 25Mg Injection

• If you have a known severe hypersensitivity or systemic allergic reaction to idarubicin, other anthracyclines, or any inactive ingredients in the formulation.
• If you have severely low blood cell counts that are not due to your underlying cancer or previous cancer treatment.
• If you have severe liver or kidney problems, depending on your doctor's assessment and the product instructions.
• If you have severe heart problems that make anthracycline treatment unsafe.
• Suppose you have an uncontrolled severe infection. Treatment may need to be delayed until the infection is controlled.

• Low white blood cell, red blood cell, and platelet counts.
• Increased chances of getting bacterial, viral, or fungal infections.
• Nausea, vomiting, stomach pain, diarrhea, and mouth or throat sores.
• Temporary loss of hair across the body.
• Red or pink urine for a short time after treatment, which is usually harmless.
• Higher liver enzyme levels in blood tests.

• Skin rash, itching, or darkening of skin and nails.
• Fever, headache, chills, and weakness.
• Irritation, pain, or inflammation near the IV line.
• Loss of appetite and dehydration, particularly if vomiting or diarrhea is significant.

• Heart failure, irregular heartbeat, or heart muscle damage, which may occur during treatment or months to years after anthracycline exposure.
• High fever, severe shivering, or life-threatening blood infection (sepsis).
• IV leakage (extravasation) causing Severe pain, blistering, or tissue damage if the medicine leaks out of the vein.
• Severe or prolonged bone marrow suppression.
• Higher risk of developing therapy-related blood cancers, such as leukemia or myelodysplastic syndrome, later in life.

• Zavedos injection must be administered exclusively by qualified medical personnel trained in the handling and administration of cytotoxic chemotherapy drugs in a specialized hospital or oncology clinic.
• Do not self-administer this medication.

• Store idarubicin vials according to the manufacturer's specified storage conditions
• Preparation, handling, and disposal must strictly adhere to hazardous waste handling procedures by authorized hospital staff.

• Expect your urine to turn reddish for a few days after infusion; this is temporary.
• Practice personal hygiene and avoid crowds and individuals with active infections.
• Report any chest pain, shortness of breath, sudden swelling, or fast heartbeats to your oncology team immediately.
• Maintain oral hygiene with a soft toothbrush to reduce mouth sores
• Attend all scheduled blood tests and cardiac assessments recommended by your doctor.

Overdose

Missed a Dose

Interactions with other medicines

• Medicines that can affect the heart, including other anthracyclines and some targeted cancer medicines, may increase the risk of heart damage with idarubicin.
• Avoid live vaccines during treatment because idarubicin can weaken the immune system and increase the risk of infection.
• Other medicines that reduce blood cell production may increase the risk of severe low blood cell counts.
• Medicines that affect liver function may change the amount of idarubicin in your body.
• Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, supplements, and herbal products you take.

Interactions with food items