Xafinact 50mg Strip Of 10 Tablets
10 Tablet(s) in StripMRP ₹170.63
₹127.97
25% OFF
Made by
SUN PHARMA
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Safinamide(50.0 Mg) |
| Uses | Parkinson's disease |
| Therapy | Anti-parkinsonian |
Assurance
available
Regulated
Medical Description
Xafinact tablet is a medicine used to treat adults with idiopathic Parkinson’s disease. It is usually prescribed along with other Parkinson’s medicines, such as levodopa, to help improve movement-related symptoms like stiffness, slowness, and tremors, and to reduce “off” periods when symptoms return between doses. Improving movement control can help patients perform daily activities more comfortably.
This medicine works by increasing the level of dopamine in the brain. It does so by selectively inhibiting monoamine oxidase B (MAO-B), which normally degrades dopamine. By preventing dopamine breakdown, Xafinact tablet prolongs its action and enhances its efficacy, supporting smoother, better-controlled movements.
Xafinact tablet should be taken exactly as advised by the doctor. It is usually swallowed whole with water and is best taken with or after food to reduce stomach-related side effects. Taking it at the same time each day helps maintain consistent benefits, and the prescribed dose should not be exceeded.
Certain precautions are important while using this medicine. Patients should inform their doctor about all other medicines they are taking, especially antidepressants, pain medicines, or drugs that affect brain chemicals, as interactions may occur. Extra caution is needed in individuals with liver disease or a history of eye or retinal disease, as the medication may not be suitable in these cases.
Some patients may notice side effects such as increased involuntary movements when taken with levodopa, or unusual behavior changes like impulsive actions or strong urges. Caregivers should also be aware of these possible changes. Xafinact tablet is generally not recommended during pregnancy or breastfeeding unless clearly advised by a doctor, due to limited safety information.
Uses
Contraindications
- If you are allergic to Safinamide or any ingredients of Xafinact tablet.
- If you are taking other medicines called monoamine oxidase (MAO) inhibitors.
- If you are using pethidine for pain relief.
- If you have severe liver disease.
- If you have certain eye conditions such as albinism, retinal degeneration, uveitis, inherited retinal disorders, or severe progressive diabetic eye disease.
Side effects
- Insomnia
- Dizziness
- Headache
- Cataract
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You are taking antidepressants like SSRIs, especially fluoxetine or fluvoxamine, as using them together with safinamide may increase the risk of serotonin-related side effects.
- You have recently stopped, or plan to start, medications such as MAO inhibitors or pain medications like pethidine, as a gap of at least 7 days is required.
- You are taking other medications that may interact with safinamide; dose adjustments or monitoring may be required.
- You have liver problems, especially moderate liver disease, as safinamide may need caution or may have to be stopped if liver function worsens.
- You have a history of eye or retinal problems, such as hereditary retinal disease or uveitis, as safinamide may not be suitable for you.
- You or your caregiver notices unusual behavior changes such as compulsive spending, gambling, increased sexual urges, or impulsive actions.
- You experience worsening involuntary movements (dyskinesia) while taking safinamide with levodopa, as your levodopa dose may need adjustment.
Directions for Use
- Xafinact tablet should be taken as directed by your doctor.
- Swallow it whole with a glass of water.
- It should be taken with or after a meal to reduce its side effects.
- It is best to take it at a fixed time for optimal results, and you should not exceed the prescribed dose.
Storage and disposal
- Store Xafinact tablet in a cool, dry place, protected from direct sunlight, moisture, and heat.
- Keep it out of the reach of children and pets.
Quick Tips
- Take Xafinact tablet exactly as prescribed and do not alter the dose independently.
- Tell your doctor about all medicines you are taking, including antidepressants and pain medicines.
- Watch for unusual symptoms such as restlessness, confusion, sweating, or muscle stiffness and report them promptly.
- Inform your physician if you have liver problems or notice signs such as yellowing of the eyes or dark urine.
- Avoid using new medicines without medical advice while on Xafinact tablet.
- Let your caregiver know to watch for behavioral changes such as impulsive actions or unusual urges.
- If you notice increased involuntary movements, inform your doctor as your treatment may need adjustment.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Do not take Xafinact tablet if you are using other MAO inhibitors (such as moclobemide), as this combination can cause a dangerous rise in blood pressure.
- Do not use Xafinact tablet together with pethidine, as this can lead to serious and harmful reactions.
- Be careful when using cold, cough, or nasal decongestant medicines (such as those containing ephedrine or pseudoephedrine), as taking them with Xafinact tablet may increase the risk of side effects.
- Avoid using cough medicines containing dextromethorphan with Xafinact tablet, or use them only with caution if absolutely necessary.
- Avoid taking certain antidepressants like fluoxetine or fluvoxamine with Xafinact tablet, as this may increase the risk of serious reactions such as serotonin syndrome.
- If antidepressants are needed, they should be used at the lowest effective dose and with careful monitoring.
- A gap (washout period) may be needed between stopping some antidepressants and starting Xafinact tablet to reduce the risk of side effects.
- Inform your doctor if you are taking medicines for depression, anxiety, or mood disorders, including SSRIs, SNRIs, or tricyclic antidepressants.
- Xafinact tablet may slightly increase plasma concentrations of certain medications, including rosuvastatin and related drugs, warranting monitoring.
- Extra caution is needed if you take medications such as metformin, aciclovir, or ganciclovir, as Xafinact tablet may increase their plasma concentrations.
- Tell your doctor if you are taking medications such as ciprofloxacin, methotrexate, or diclofenac, or diabetes medications such as glyburide, as dose adjustment or monitoring may be required.
- Always inform your doctor about all prescription medicines, over-the-counter drugs, and herbal products you are using before starting Xafinact tablet.
Interactions with food items
- Xafinact tablet can be taken with or without food.
- No strict food restrictions are usually needed.
- Avoid excessive consumption of aged or fermented foods.
- Limit alcohol to reduce dizziness or drowsiness.
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Manufacturer Details
Brand:XAFINACT
Manufacturer Name:SUN PHARMA
Address:Sun Pharma Laboratories Ltd,Vill Kokjhar, Mirza Palashbari Road.P.O..Palashbari Dist : Kamrup Assam-781128
Country of Origin:India
Vendor Details
Fulfillment Information: Xafinact 50 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Central Drugs Standard Control Organization (CDSCO). Drugs: Approved Drugs / Vaccines / r-DNA / Blood Products [Internet]. Government of India; [cited 2025 Dec 29].
- MSN Laboratories Europe Ltd. Safinamide 50 mg film-coated tablets: Summary of Product Characteristics [Internet]. UK: Datapharm Ltd.; 2025 Nov 24 [cited 2025 Dec 29].
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