Tonact-ASP 75 Capsule

• If you have any allergic reaction to Atorvastatin, Aspirin or any of the ingredient of Tonact-ASP 75 capsule.
• If you have bleeding disorders.
• If you have a history of ulcer in the stomach or small intestine.
• If you have gout.
• If you have kidney or liver problems.
• If you are pregnant (last three months) or breastfeeding.
• If you are taking medicines for cancer or rheumatoid arthritis (like methotrexate - more than 15mg per week).
• If you are being treated with medicines for hepatitis C like Glecaprevir/ Pibrentasvir.

• Headache
• Nausea
• Diarrhoea
• Body pain (joint, back, throat, muscle)
• Swelling of nasal passages and bleeding from the nose
• Indigestion, heartburn and nausea
• Increased risk of bleeding
• Itching
• Breathing difficulty
• Abnormal liver function and increased creatinine level

Other General Warnings

• You have liver or kidney disease.
• You experience muscle pain, cramps, weakness and fever after taking this medicine, immediately inform your doctor.
• You experience any muscle problems after taking other lipid-lowering medicine.
• You have breathing difficulty.
• You are addicted to alcohol.
• You have any thyroid problems.
• You are undergoing surgery or had an operation recently.
• You have any unusual bleeding.
• You notice black tarry stools or blood in vomit.
• You have asthma, this medicine can worsen your asthma.
• You have high blood pressure.
• You have ulcers in your stomach or small intestine.
• you are suffering from gout.
• You experience heavy menstrual bleeding, do not take this medicine as it can increase the bleeding.
• You are taking medicine for bacterial infection like fusidic acid as this may cause serious muscle injury.
• You have diabetes, a regular blood glucose check-up is needed.

• Store Tonact-ASP 75 capsule at or below 30°C in a cool dry place.
• Keep out of reach of children and pets.
• Check expiry date before starting the treatment.

Overdose

• Symptoms of overdose of Tonact-ASP 75 capsule include ringing in the ears, dizziness, headache, nausea, vomiting and stomach ache, sweating, fever, increased pulse or breathing rate, fits and low blood sugar.
• In case of an overdose, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

How Does It Work?

• Cholesterol is made by the enzyme HMG-CoA reductase. Atorvastatin inhibits this enzyme. Therefore, lowering cholesterol and bad cholesterol (LDL levels). It also increases the good cholesterol known as high-density lipoprotein (HDL levels).
• Aspirin in low doses stops the platelets from forming a clot so that the blood can flow without any obstruction in the arteries.

Interactions with other medicines

• Tonact-ASP 75 capsule contains Atorvastatin and Aspirin. Any interactions that are seen with these two components when taken alone may occur with this combination.
• Never take Tonact-ASP 75 capsule with hepatitis medicines like Glecaprevir/ Pibrentasvir.
• Medicines used for thinning of the blood (e.g. Warfarin) can increase the risk of bleeding.
• Increased risk of muscle damage and serious side effects if taken with Niacin, Cyclosporine, Clarithromycin, Itraconazole, Tacrolimus and Ezetimibe.
• Medicines used to treat high blood pressure or any heart problems like Amlodipine and Digoxin can increase the side effects of Tonact-ASP 75 capsule.
• Tonact-ASP 75 capsule may interfere with medicines used for high blood pressure like Ramipril and Lisinopril.
• Avoid the use of painkillers as it can lead to stomach bleeding.

Interactions with food items