Tazloc-CT 40 Tablet

• Treatment of high blood pressure

• As this medicine contains Chlorthalidone and Telmisartan, any condition which is contraindicated with any of these when taken alone should be considered contraindicated for this combination
• If you are allergic to Telmisartan or Chlorthalidone or any of the ingredient of this medicine
• If you are allergic to antibiotics like Sulfasalazine and other drugs from this class
• Should not be taken by pregnant & breastfeeding women
• If you have serious liver disorders and problems related to bile duct (canal connecting liver to intestine) like cholestasis
• If you feel difficulty in passing urine or passing no urine at all (anuria)
• If your blood test shows a significant increase in calcium and decrease in potassium levels
• If you have diabetes or kidney problem and you are taking medicine for lowering the blood pressure like Aliskiren

• Muscle and back pain
• Loose stools
• Gas
• Fainting
• Breathlessness
• Tingling sensation
• Cough
• Anemia
• Peeling of skin and formation of blisters

Other General Warnings

• If you experience fainting, giddiness especially after the first dose
• If you are planning a pregnancy, this medicine will be changed
• If you are facing problems with liver function and related organs-like cholestasis and biliary obstructive
• If your kidneys are not functioning properly or you have underlying kidney disease like renal artery stenosis (Narrow kidney blood vessels)
• If you have been experiencing fluid losses within your body due to diarrhoea, vomiting, etc.
• If you have serious heart and heart valve-related problems like congestive heart failure, aortic or mitral stenosis and ischaemic cardiopathy
• If you are suffering from primary aldosteronism (a condition of excess production of the hormone aldosterone from the adrenal glands)
• If you have diabetes as this medicine may affect your blood glucose levels, glucose monitoring is needed
• If you have electrolyte imbalance of sodium, magnesium, potassium and have symptoms of dryness of mouth, thirst, drowsiness, muscle pain, nausea, vomiting, etc.

• This medicine should be consumed as a whole with a sufficient amount of water with or without food
• Do not change your dose unless your doctor tells you to do. Never stop this medicine on your own
• This medicine tends to catch moisture. Thus, it should be taken out from blister just before use

• Store it below 25°C and try to keep it in the original packaging to protect it from sunlight and moisture
• Keep out of sight and reach of children

Overdose

Missed a Dose

• It would be best if you never miss a dose of your blood pressure medicine as it may lead to serious high blood pressure-related problems
• If you missed any dose, take it as soon as you remember
• If it is time for the next dose, skip the missed dose and continue with your regular dosing schedule
• Do not take a double dose of medicine to compensate for the missed one

How Does It Work?

• Telmisartan lowers the blood pressure by blocking the action of a hormone called angiotensin, responsible for narrowing of blood vessels and rise in blood pressure
• Chlorthalidone acts by increasing the production of urine and loss of water and salt from the body, thereby lowering the blood pressure

Interactions with other medicines

• There is limited information available on the interaction of this combination with other drugs. However, as this medicine contains Chlorthalidone and Telmisartan, any interactions seen with these two components when taken alone may occur with this combination
• Medicine used for heart failure like Digoxin should be used cautiously
• Your blood potassium levels may go down if you are taking Spironolactone, Eplerenone, Triamterene or Amiloride, potassium supplements or potassium-containing salt substitutes
• Medicines used to treat mental illness like Lithium, Thioridazine and Chlorpromazine
• Your blood potassium levels may increase if you are taking water tablets, Losartan, Aliskiren and immunosuppressants like Cyclosporin or Tacrolimus and Trimethoprim and Heparin
• You may experience low blood sugar if you are taking medicine for diabetes like Insulin and Metformin along with this medicine (severe kidney problems may also arise with metformin)
• This medicine can decrease your blood pressure abruptly if taken with other blood pressure-lowering medicine
• Medicines used to treat pain and inflammation like Aspirin, Ibuprofen and Naproxen interferes the way this medicine works
• Medicines used to relax muscle like Tubocurarine. This medicine can increase blood calcium levels if you are taking vitamin D and calcium supplements
• Other medicines which may not be able to work properly like Quinidine, Digoxin, Sotalol and Norepinephrine