Sematrinity 2Mg Pre Filled Pen Of 1.5Ml Solution For Injection

• It is used to treat type 2 diabetes in adults
• Used along with diet & exercise to help control blood sugar levels

• Alone (if other medicines like metformin are not suitable)
• Along with other diabetes medicines

• Sematrinity solution for injection is contraindicated in patients with:
• A personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• A known allergy to semaglutide or any of the excipients in Sematrinity solution for injection.

• Nausea (feeling sick)
• Diarrhea
• Vomiting
• Stomach pain
• Constipation
• Indigestion
• Reduced appetite

• Headache or dizziness
• Low blood sugar (especially with insulin or other diabetes drugs)
• Increased heart rate
• Fatigue
• Injection site reactions

• Pancreatitis (severe stomach pain)
• Allergic reactions (rash, swelling, breathing difficulty)
• Eye problems in diabetic patients

Other General Warnings

• You have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• You experience symptoms of thyroid tumors (e.g., a mass in the neck, difficulty swallowing, difficulty breathing, persistent hoarseness).
• You experience persistent severe abdominal pain, sometimes radiating to the back, and which may or may not be accompanied by vomiting (symptoms of acute pancreatitis).
• You experience symptoms of gallbladder disease, such as cholelithiasis or cholecystitis.
• You have diabetes and experience signs or symptoms of hypoglycemia (low blood sugar), especially if you are taking insulin or a sulfonylurea.
• You experience severe gastrointestinal reactions (nausea, vomiting, or diarrhea) that could lead to dehydration.
• You have kidney impairment and experience any adverse reactions that could lead to volume depletion.
• You experience signs or symptoms of a serious allergic reaction (e.g., anaphylaxis, angioedema).
• You have a history of diabetic retinopathy.
• You experience palpitations or a racing heartbeat at rest.
• You experience the emergence or worsening of depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior.
• You have a history of suicidal attempts or active suicidal ideation.
• You planning any elective surgeries or procedures requiring general anaesthesia or deep sedation?

• Given as a weekly injection under the skin (subcutaneous)
• Inject into the stomach (abdomen), thigh, or upper arm.
• Can be taken with or without food
• Follow the dose schedule as decided by your doctor

• Store in refrigerator (2–8°C)
• Do not freeze
• After first use: Can be kept at room temperature (below 30°C) or in a refrigerator (2–8°C)
• Keep away from light
• Dispose 2mg/1.5 ml and 4mg/3ml pen 56 days after first use
• Keep away from children

• Sematrinity 2mg Pre-filled Pen is a once-weekly injection. Always administer it on the same day each week, and carefully follow your doctor's prescribed dose increase schedule to minimize side effects. Do not raise your dose faster than advised.
• Nausea, vomiting, diarrhea, and constipation are common, especially when beginning treatment. Drink plenty of fluids to prevent dehydration. If side effects are severe or persistent, contact your doctor immediately. Eating smaller meals, avoiding greasy foods, and staying hydrated can help.
• Be aware of signs of serious side effects like severe abdominal pain (pancreatitis), symptoms of gallbladder issues, severe allergic reactions, or changes in mood/thoughts (e.g., depression, suicidal ideation). Report any concerning symptoms to your doctor straight away.
• Keep your healthcare provider informed about all medications you're taking, any new or worsening health conditions, and how you're feeling while taking Sematrinity 2mg Pre-filled Pen. Regular follow-ups are crucial for monitoring your progress and addressing any potential issues.

Overdose

• Taking too much may cause severe nausea and vomiting.
• There is no specific antidote.
• Supportive treatment should be given; medical supervision is needed.

Missed a Dose

• This medicine works like a natural hormone in your body.
• It increases insulin when blood sugar is high, reduces the release of sugar from the liver, slows digestion so sugar enters the blood more gradually, and helps reduce appetite and body weight.

Interactions with other medicines

• Sematrinity Injection 2mg/1.5mL affects how other oral medicines get absorbed (because it slows digestion)
• Use with caution when taking insulin or sulfonylureas (risk of low blood sugar), blood thinners (monitor required).
• Generally safe with Metformin, Statins, and Oral contraceptives (birth control pills)