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Pomyelo 4 Bottle Of 21 Capsules

21 Capsule(s) in Bottle

MRP15805.22

13774.70

13% OFF

655.94/capsule (Inclusive of all taxes)
15 days return policy Read More
Offer applicable on order above ₹1000
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INTAS PHARMACEUTICALS LTD

Dosage

CAPSULE

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Product Summary

Uses
Multiple myeloma
Therapy
Anti-neoplastic
Side effects
Constipation, diarrhea, nausea, and decreased appetite
Salt Content
Pomalidomide(4.0 Mg)
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Pomyelo capsule contains pomalidomide, a prescription oral anticancer medicine that belongs to a group called immunomodulatory drugs (IMiDs). It is mainly used with dexamethasone to treat adults with multiple myeloma that has returned or stopped responding to treatment after at least two previous therapies, including lenalidomide and bortezomib. Pomalidomide works in several ways. It binds to a protein called cereblon, which helps break down certain proteins involved in cancer-cell growth. It also helps strengthen the immune system's T-cell and natural killer (NK) cell activity against myeloma cells and may reduce the formation of new blood vessels that support tumour growth.

Treatment requires close medical supervision and regular blood tests, as pomalidomide can cause low blood cell counts, particularly neutropenia and thrombocytopenia, and can increase the risk of blood clots.

Pomalidomide can cause severe birth defects and must not be used during pregnancy. Strict pregnancy-prevention measures are required for patients who can become pregnant, and appropriate contraception is also required for male patients according to the applicable pregnancy-prevention programme.

Uses

Treatment of relapsed and refractory multiple myeloma in adult patients who have received at least two prior treatment regimens, including both lenalidomide and bortezomib, and have demonstrated disease progression on the last therapy.

Contraindications

  • During pregnancy, pomalidomide can cause serious birth defects or harm to the developing baby.
  • If you are a male patient who is unwilling or unable to follow the required contraceptive precautions.
  • If you have a severe allergy or hypersensitivity to pomalidomide or any of its ingredients.
  • Safety note: Women who can become pregnant must follow the pregnancy-prevention requirements and undergo pregnancy testing as advised by their doctor before and during treatment.

Side effects

Very common side effects (occurring frequently):
  • Bone marrow suppression leading to neutropenia (low white blood cell counts, increasing infection risk), anemia, and thrombocytopenia (low platelets)
  • Fatigue, asthenia (weakness), and pyrexia (fever)
  • Constipation, diarrhea, nausea, and decreased appetite
  • Peripheral edema (swelling in the hands, ankles, or feet)
  • Upper respiratory tract infections and cough
  • Muscle spasms and back pain
Other reported side effects:
  • Dizziness, tremor, and peripheral neuropathy (numbness or tingling)
  • Shortness of breath (dyspnea)
  • Rash and dry skin
  • Insomnia and confusion
Serious but less common side effects:
  • Severe teratogenicity (life-threatening birth defects or fetal death)
  • Deep Vein Thrombosis (DVT) and Pulmonary Embolism (blood clots)
  • Severe, life-threatening neutropenic fever and serious infections (such as pneumonia or sepsis)
  • Severe cutaneous reactions (such as Stevens-Johnson syndrome)
  • Hepatotoxicity (liver enzyme elevations or liver injury)
  • Tumor lysis syndrome

Precautions and Warnings

Pregnancy

Pregnancy

No. Pomyelo capsule can cause severe birth defects and must not be used during pregnancy. Women who can become pregnant must use effective contraception and regular pregnancy testing as required by the pregnancy-prevention programme.Male patients should use condoms during treatment and for the period advised by their doctor in the specified circumstances.

Breast Feeding

Breast Feeding

Breastfeeding is not recommended during treatment with Pomyelo capsule because it is not known whether pomalidomide passes into breast milk and it may cause serious harm to the baby. Discuss your options with your doctor.

Alcohol

Alcohol

Alcohol may worsen fatigue or dizziness. Discuss alcohol use with your doctor during treatment.

Driving

Driving

Use caution. Pomyelo capsule can cause side effects such as fatigue, dizziness, and confusion that may impair your alertness. Avoid driving or operating machinery if you feel unwell.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You develop a fever, chills, or signs of an infection while your blood counts are low.
  • You notice sudden swelling, pain, or redness in your arms or legs, or experience chest pain (signs of blood clots).
  • You experience severe skin rashes, blistering, or peeling.
  • You notice yellowing of the skin or eyes, dark urine, or upper abdominal pain (signs of liver issues).

Directions for Use

  • Swallow the capsules whole with a glass of water; do not open, break, crush, or chew them.
  • You may take this medication either with or without food.
  • Continue your treatment course precisely as scheduled under your strict risk management program; never alter your dose without consulting your physician.

Storage and disposal

  • Store the capsules at room temperature (below 30°C) in their original blister packaging, protected from moisture and light.
  • Keep out of the reach of children and pets in a secure medical environment.
  • Do not keep expired or unwanted capsules; return unused medicine directly to your doctor or pharmacist according to your program guidelines. Never share this medication.

Quick Tips

  • Strictly adhere to your mandatory pregnancy prevention program and contraceptive requirements if you are a patient of childbearing potential.
  • Keep all scheduled blood test appointments so your doctor can monitor your white blood cell counts and platelet levels before every cycle.
  • Report any fever, chills, sore throat, or signs of infection to your medical team immediately.
  • Watch for warning signs of blood clots, such as sudden pain, swelling, or redness in your leg, or sudden shortness of breath and chest pain.
  • Inform all your healthcare providers that you are taking this medication before undergoing any medical procedures or surgeries.

Dosage

Missed a Dose

If you miss a dose of Pomyelo capsule and it has been less than 12 hours since your scheduled time, take it as soon as you remember. If it has been more than 12 hours, skip the missed dose and take your next dose at the normal time the following day. Never take a double dose to make up for a missed dose.

Overdose

If an overdose is suspected, emergency medical intervention must be initiated immediately in a hospital setting. Management involves supportive hospital care, vital sign monitoring, and symptomatic treatment.

How does this medicine work?

Pomyelo capsule is an immunomodulatory medicine that works in several ways to fight multiple myeloma.It binds to a protein called cereblon, which helps break down certain proteins that myeloma cells need to survive. This can cause myeloma cells to stop growing and die.Pomalidomide also strengthens the immune response by activating T cells and natural killer (NK) cells and may reduce the formation of new blood vessels that help tumours grow.

Interactions

Interactions with other medicines

  • Ciprofloxacin and fluvoxamine: These may increase pomalidomide levels and the risk of side effects. They should generally be avoided; if necessary, your doctor may reduce the pomalidomide dose.
  • Carbamazepine: This may lower pomalidomide levels and could reduce its effectiveness.
  • Dexamethasone: It is commonly used with pomalidomide and does not significantly affect pomalidomide levels.
  • Tell your doctor about all prescription and over-the-counter medicines, vitamins, supplements, and herbal products you take before starting treatment.

Interactions with food items

  • You can take the capsules with or without food, depending on your daily schedule.
  • Maintain a well-balanced, high-fiber diet and stay thoroughly hydrated to help manage constipation and fatigue.

Frequently Asked Questions (FAQs)

Pomalidomide is related to thalidomide and can cause severe birth defects or fetal death if a pregnancy is exposed. Strict contraception and regular pregnancy testing are therefore required to prevent accidental exposure during treatment.
Pomalidomide frequently causes bone marrow suppression, leading to temporary drops in your white blood cells (neutropenia), platelets, and red blood cells. Regular blood tests ensure your counts are safe before you start each new treatment cycle.
Pomalidomide, especially when used with dexamethasone, can increase the risk of blood clots. Your doctor will assess your risk and may prescribe aspirin or another blood-thinning medicine to help prevent clots if appropriate.

References:

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Manufacturer Details

Brand:POMYELO

Country of Origin:India

Vendor Details

Fulfillment Information: Pomyelo 4 MG Capsule (21) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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