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Pomalidomide

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Molecule Summary

Uses
Cancer
Therapy
Anti-Neoplastic
Side Effects
Dizziness, fatigue, constipation, infection
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Molecule Description

Pomalidomide is an immunomodulatory medicine. It modulates the immune system. Pomalidomide is used to treat white blood cell cancer along with dexamethasone in patient who have been treated earlier with two other therapies. After completion of the prior two therapies, the disease has still progressed. This medicine modulates and strengthens the immune system. It kills and inhibits the growth of cancer cells thereby prevents the spread of cancer. Take Pomalidomide as advised by your doctor. Do not stop taking this medicine on your own. Pomalidomide should be avoided if you are pregnant or planning pregnancy.

Uses

Used to treat cancer of white blood cell in patients who have been treated with two therapies, including lenalidomide and bortezomib (proteasome inhibitor), the disease has progressed after completion of the prior treatment.

Contraindications

When should one not use Pomalidomide

  • If you are allergic to pomalidomide or any other ingredient of Pomalidomide.
  • If you are pregnant, planning pregnancy or of a child bearing age.

Side effects

Common side effects of this drug are:

  • Fatigue
  • Constipation
  • Vomiting
  • Pneumonia
  • Anaemia
  • Decreased blood count
  • Dizziness
  • Difficulty in breathing
  • Nausea
  • Rash

Precautions and Warnings

Pregnancy

Pregnancy

Pomalidomide should not be used during pregnancy as it may cause serious harm to the unborn baby. Inform your doctor if you are planning pregnancy while on this medicine.

Breast Feeding

Breast Feeding

It is not known if the component of Pomalidomide passes into the breastmilk. It is advised to avoid breastfeeding while on this medicine.

Driving

Driving

You should avoid driving if you feel tired, dizzy or sleepy after taking Pomalidomide.

Alcohol

Alcohol

No, you should not consume alcohol while on Pomalidomide as it may worsen the side effects. Talk to your doctor if you consume it often.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are above 50 years of age, menopausal or of a non-child bearing age.
  • You are using any kind of contraceptive method.
  • You are pregnant or breastfeeding.
  • You have heart disease or conditions, blood clot in the body.
  • You have thyroid, blood disorder.
  • You have viral reactivation or visual disturbance such as cataract.
  • You have kidney or liver damage.
  • You experience any allergic reaction after taking Pomalidomide.
  • You have or experience tingling sensation or numbness of the extremities.
  • You have or had any kind of cancer or tumour lysis syndrome.
  • You have any active infection.
  • You feel sleepy or dizzy.
  • You are smoking, as smoking may reduce the effectiveness of Pomalidomide.
  • Pomalidomide should not be used for children below 18 years of age.

Mode of Action

How Does It Work?

  • Pomalidomide acts by inhibiting the growth and multiplication of cancer cells and stops cancer cells from making their own blood vessels. Thus, kills the cancer cells.
  • It works by killing the abnormal cells in the bone marrow and helps to produce healthy normal blood cells.

Interactions

Interactions with other medicines

  • Some medicines affect the way Pomalidomide works or Pomalidomide itself reduces the effectiveness of other medicines taken at the same time.
  • Inform the doctor about other medicine, herbal preparation and supplements you are taking to avoid possible interactions.
  • Especially if you are taking oral contraceptive medicines, blood thinners, anti-allergic medicine, other cancer medicine, antifungal, antibiotic or medicine used to treat brain related disorder.

Dosage

Overdose

If you think you have taken too much of Pomalidomide contact your doctor immediately or visit the nearest hospital.

Missed a Dose

Missing a dose of Pomalidomide may reduce the effectiveness of the treatment. If you missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Do not stop taking Pomalidomide until and unless your doctor advises you. If you stop taking this medicine, it can lead to an incomplete killing of cancer cells and thus increase the risk of the recurrence of cancer. The doctor will gradually decrease the dose as per the need.

No, Pomalidomide is not a steroid medicine. It is an anti-cancer medicine used to treat white blood cell cancer along with dexamethasone.

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