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Neorof 1% Injection 10Ml

10ml Injection in Vial
We do not sell this product

Made by

NEON LABORATORIES LIMITED

Dosage

INJECTION

Expiry

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Product Summary

Salt Content
Propofol(1.0 %)
Uses
Induction and maintenance of general anaesthesia, For conscious sedation for surgical and diagnostic procedures, For sedation of ventilated patients receiving intensive care.
Therapy
General anaesthesia
Side effects
Nausea, vomiting, headache, decrease in heart, decrease in blood pressure, pain at the injection site, skin rash
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Neorof Injection is used to administer general anaesthesia. Its active ingredient is propofol. It is issued only by an anaesthetist at the time of major surgeries to render the patient unconscious and safely carry out any surgical procedure. Neorof can also maintain the anaesthesia for a longer duration during surgery, known as maintenance. In some cases, such as when patients need additional support to breathe in the form of a ventilator or tube, a general anaesthetic agent is required to ensure the effective functioning of the device. Sometimes for minor procedures, Neorof can be used only to provide pain relief while the patient is conscious. This is an intravenous injection and is only administered by trained medical professionals.

Uses

  • As per CDSCO,
  • Induction and maintenance of general anaesthesia.
  • For conscious sedation for surgical and diagnostic procedures
  • For sedation of ventilated patients receiving intensive care.

Contraindications

  • If you have a known hypersensitivity to propofol or any of its components.
  • If you are allergic to eggs, egg products, soybeans, or soy products.

Side effects

  • Nausea
  • Vomiting
  • Headache
  • Changes in blood pressure
  • Decreased Cardiac Output
  • Pain at the injection site
  • Skin rash
  • Stopping of respiratory activity

Precautions and Warnings

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Pregnancy

Neoref injection can cross the placenta and affect the fetus, but it has been safe when used in pregnant patients under a doctor's care.

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Breast Feeding

Neorof Injection is not recommended for use in nursing mothers because propofol has been reported to be excreted in human milk, and the effects of oral absorption of small amounts of propofol are not known.

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Driving

Neorof Injection cannot be used during driving as it is general anaesthetic and sedative medicine.

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Alcohol

It is strongly contraindicated, as it is a general anaesthetic and sedative medicine

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Other General Warnings

Talk to your doctor if
  • You have any food allergies.
  • You should disclose the concurrent use of any other medications.

Directions for Use

  • Shake well before use.
  • Do not use if there is clumping or aggregation, if large droplets are seen, or if there are other forms of phase separation indicating that the stability of the product has been compromised.
  • Slight creaming may be visible upon prolonged standing, but it should disappear on shaking.
  • Neorof Injection must be prepared for use just before the start of each anaesthetic/sedative procedure.
  • The vial rubber stopper should be disinfected using 70% isopropyl alcohol.
  • Neorof Injection should be drawn into a sterile syringe immediately after a vial is opened.
  • When withdrawing Neorof Injection from vials, a sterile vent spike should be used.
  • The syringe should be labelled with details, including when the vial was opened.
  • The administration should commence promptly and be completed within 12 hours after the vial has been opened.

Storage and disposal

Store it between 4° to 25°C (40° to 77°F). Do not freeze. Shake well before use. Keep in a dry and cool place.

Dosage

Overdose

If an overdose occurs, Neorof Injection administration should be discontinued immediately. Overdose symptoms include cardiorespiratory depression, i.e., decreased blood pressure, difficulty breathing or a dramatic rise in body temperature, flushed skin, sweating, or a rapid increase in heart rate. In rare cases, if the injection is given for too long, it can cause fatal toxicity. Appropriate management by the anaesthetist is advisable.

Missed a Dose

The injection should only be administered at the discretion of an anaesthetist for use during or prior to a procedure. Incorrect maintenance may cause the patient to regain consciousness.

Mode of Action

How Does It Work?

The exact mechanism of action is poorly understood. It acts on specific chloride channels in the brain mediated by a chemical substance known as GABA. It is postulated that propofol helps bind GABA to these chloride channels for longer. Because of this, the channel remains active for a long time, and an inhibitory effect is seen.

Interactions

Interactions with other medicines

  • Other medications that affect blood pressure or heart rhythm
  • Medications that cause slowing down respiratory rate, such as opioids.

Interactions with food items

  • The patient must be fasting for 12 hours before surgery for general anaesthesia or as advised by the physician for individual procedures.

Frequently Asked Questions (FAQs)

The exact duration of anaesthesia varies from patient to patient and depends upon the duration of the procedure and the dose of the agent administered.

Neoref injection can be used in different ways for many major surgical procedures. It should only be administered by a trained anaesthetist.

Patients who cannot breathe well may require the support of a ventilator. At this time, agents such as Neoref are used to sedate the patient to ensure the machine works well. The procedure is only done under the care of an anaesthetist or ICU specialist doctor.

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Manufacturer Details

Brand:NEOROF

Country of Origin:India

Vendor Details

Fulfillment Information: Neorof 1 % Injection (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

References:

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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