Naprosuma Tablet 2'S
Description
Naprosuma Tablet is a combination medicine containing Sumatriptan and Naproxen. It is used in the treatment of headache associated with migraine with or without warning signs. Sumatriptan works by na
rrowing the blood vessels in the brain which helps in getting relief from migraine headache. Naproxen works by reducing pain and swelling by decreasing the synthesis of a natural substance called prostaglandin, which is responsible for swelling and pain. Nausea, dizziness, sleepiness, chest pain, neck/jaw/throat pain or tightness, indigestion are some of the side effects of Naprosuma Tablet.
Product Summary
Offer Price | ₹74.82 |
You Save | ₹11.18 (13% on MRP) |
Contains | Sumatriptan(85.0 Mg)+Naproxen(500.0 Mg) |
Therapy | MIGRAINE DRUGS |
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Uses
Contraindications
- If you are allergic to sumatriptan, naproxen or any other ingredients of this medicine.
- If you have decreased blood supply to the heart, brain or other parts of the body.
- If you have severe liver disease.
- If you have high blood pressure which is not under control.
- If you have a migraine headache associated with weakness on one side of the body.
- If you have migraine headache pain present over the backside of the head.
Side effects
- Nausea
- Dizziness
- Sleepiness
- Chest pain
- Indigestion
- A dry mouth
- An abnormal sensation over the skin
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have high blood pressure, diabetes, high blood cholesterol level, dehydration, heart disease or a family history of heart disease.
- You are obese, a smoker.
- You are a female whose menstruation is stopped normally or due to the removal of the uterus.
- You are a male over 40 years of age.
- You have chest pain, jaw or neck tightness, giddiness, difficulty in breathing, slurring of speech, headache, abdominal pain, blood in stool, vision problem after taking this medicine.
- You have swelling over your body after taking this medicine.
- You have asthma, kidney disease or liver diseases.
- You have nausea, tiredness, skin rash, itching or fever after taking this medicine.
- You have a history of epilepsy, a brain disorder characterised by recurrent seizure.
- You have indigestion, stomach pain, blood in vomit or stool after taking this medicine.
Mode of Action
How Does It Work?
- Sumatriptan works by narrowing some blood vessels in the brain which helps in relief of migraine headache.
- Naproxen works by reducing pain and swelling by decreasing the synthesis of a natural substance called prostaglandin, which is responsible for swelling and pain.
Directions for Use
Interactions
Interactions with other medicines
- Some medicines can affect the way Naprosuma Tablet works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
- Especially, if you are taking medicines for brain diseases, heart disease or any anticancer medicines.
Storage and disposal
- Store it at 15°C to 30°C in a cool and dry place.
- Keep it out of the reach of children and pets.
Dosage
Overdose
Missed a Dose
Content Details

Dr. Arpit Verma
MBBS, MD CCEBDM Diabetology

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can Naprosuma Tablet be used for the prevention of a migraine headache?
Q: Can I use Naprosuma Tablet for treatment of any type of headache?
Q: Does Naprosuma Tablet cause sleepiness?
Q: Does Naprosuma Tablet make my headache worse?
References
- USPI. Sumatriptan+Naproxen.2025 [cited 27 Mar 2025].(online)
- CDSCO. Sumatriptan+Naproxen.2025 [cited 27 Mar 2025].(online)
- Khoury CK, Couch JR. Sumatriptan-naproxen fixed combination for acute treatment of migraine: a critical appraisal. Drug Des Devel Ther. 2010 Feb 18;4:9-17. [cited 27 Mar 2025].
- Law S, Derry S, Moore RA. Sumatriptan plus naproxen for the treatment of acute migraine attacks in adults. Cochrane Database Syst Rev. 2016 Apr 20;4(4):CD008541. [cited 27 Mar 2025].
- U.S. Food and Drug Administration. N21-926S012-Sumatriptan-Naproxen-Clinical-BPCA [Internet]. 2025 [cited 27 Mar 2025].
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