Sumatriptan+Naproxen
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Molecule Summary
| Uses | Migraine |
| Therapy | Migraine Drugs |
| Side Effects | Nausea, dizziness, sleepiness, chest pain |
Medicines
available
19k pincodes
Molecule Description
Sumatriptan+Naproxen is used to relieve headaches caused by migraines, with or without early warning signs (aura). It is a combination of two medicines, sumatriptan and naproxen, that work together to provide faster and longer-lasting relief.
Sumatriptan works by narrowing the blood vessels in the brain, which helps reduce the headache and other migraine symptoms. Naproxen is a pain-relieving medicine that reduces swelling and discomfort by blocking a natural substance called prostaglandin, which is responsible for pain and inflammation.
Common side effects of Sumatriptan+Naproxen include nausea, dizziness, sleepiness, and indigestion. These effects are usually mild and go away on their own, but if they continue or get worse, you should speak to your doctor.
Before starting this medicine, inform your doctor if you have any heart problems, stomach or intestinal disorders, or any other serious health conditions. Sumatriptan+Naproxen may not be suitable in such cases, and your doctor may recommend an alternative.
Do not use Sumatriptan+Naproxen longer than the recommended duration.
Uses
Sumatriptan+Naproxen is used in the treatment of a headache associated with migraine with or without warning signs.
Contraindications
When should one not use Sumatriptan+Naproxen
- If you are allergic to sumatriptan, naproxen or any other ingredients of Sumatriptan+Naproxen.
- If you have decreased blood supply to the heart, brain or other parts of the body.
- If you have severe liver disease.
- If you have high blood pressure which is not under control.
- If you have a migraine headache associated with weakness on one side of the body.
- If you have migraine headache pain present over the backside of the head.
Side effects
Common side effects of this drug are:
- Nausea
- Dizziness
- Sleepiness
- Chest pain
- Indigestion
- A dry mouth
- Abnormal sensation over the skin
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have high blood pressure, diabetes, high blood cholesterol level, dehydration, heart disease or a family history of heart disease.
- You are obese, a smoker.
- You are a female whose menstruation is stopped normally or due to the removal of the uterus.
- You are a male over 40 years of age.
- You have chest pain, jaw or neck tightness, giddiness, difficulty in breathing, slurring of speech, headache, abdominal pain, blood in stool, and vision problems after taking this medicine.
- You have swelling all over your body after taking this medicine.
- You have asthma, kidney disease or liver disease.
- You have nausea, tiredness, skin rash, itching or fever after taking Sumatriptan+Naproxen.
- You have a history of epilepsy, a brain disorder characterised by recurrent seizures.
- You have indigestion, stomach pain, blood in vomit or stool after taking this medicine.
Mode of Action
How Does It Work?
- Sumatriptan works by narrowing some blood vessels in the brain which helps in the relief of migraine headaches.
- Naproxen works by reducing pain and swelling by decreasing the synthesis of a natural substance called prostaglandin, which is responsible for swelling and pain.
Interactions
Interactions with food items
It is recommended to take Sumatriptan+Naproxen with food. Taking it with food can help to avoid stomach-related issues.
Dosage
Overdose
Symptoms of an overdose include dizziness, sleepiness, stomach pain, indigestion, nausea, increase in headache, etc. If you have taken too much of Sumatriptan+Naproxen then contact your doctor or reach out to the nearest hospital immediately.
Missed a Dose
If you have missed taking any dose of Sumatriptan+Naproxen, then take it as soon as you remember it. If it's already time for the next dose then skip the missed dose and follow your regular dosing schedule.
Frequently Asked Questions (FAQs)
Articles
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References:
- Sumatriptan and naproxen [Internet]. Accessdata.fda.gov. 2021 [cited 8 June 2026]
- Sumatriptan 50mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 8 June 2026]
- Sumatriptan 50mg film-coated tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 8 June 2026]
- Naproxen 500 mg tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 8 June 2026]
- Naproxen 500 mg tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2026 [cited 8 June 2026]
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