Misogesic Sr Strip Of 10 Tabletss
10 Tablet(s) in StripWe do not sell this product
Made by
ICARUS HEALTH CARE PVT LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Misoprostol(100.0 Mcg)+Diclofenac(100.0 Mg) |
| Uses | Pain management |
| Therapy | Drugs for osteoarthritis, drugs for rheumatoid arthritis |
| Side effects | Abdominal pain, Loose stools, Dyspepsia, Nausea, Flatulence, Gastritis, Vomiting, Constipation, Headache, Dizziness |
Assurance
available
Regulated
Medical Description
Misogesic SR tablet is a prescription medication. It is a potent analgesic or painkiller. The active components of Misogesic SR tablets are Diclofenac and Misoprostol. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug) painkiller, whereas Misoprostol is a prostaglandin analogue that serves as a gastro-protective agent.
This medication is primarily used to relieve moderate to severe pain in conditions that affect joints like osteoarthritis and rheumatoid arthritis. These conditions may present with symptoms like joint swelling, pain, restriction of joint movement etc. It can also be helpful in pain management of other diseases like ankylosing spondylitis, gout, post-operative pain, post-dental surgery etc.
The doctor’s directions for use of Misogesic SR tablets should be strictly followed. Take this medication as recommended by your doctor. This medication should not be abruptly started or stopped. Take this medication regularly as prescribed by your doctor for maximum effects. If you are pregnant or currently breastfeeding, inform your doctor of the same. Side effects of Misogesic SR tablets include abdominal pain, loose stools, indigestion, nausea, flatulence, gastritis, etc.
Uses
- Misogesic SR tablets are used to:
- Manage pain in conditions like osteoarthritis and rheumatoid arthritis
- Manage pain in ankylosing spondylitis, gout, post-operative pain, post-dental surgery, etc.
Contraindications
- If you are pregnant. This medication is strictly contraindicated in pregnancy and those intending to conceive. It can result in abortions, premature birth, and birth defects. This is due to the activity of misoprostol on the uterine muscles. It can even result in a fatal rupturing of the uterus.
- If you have hypersensitivity reactions to this medicine's active or inactive ingredients.
- If you have a history of asthma. This medication is contraindicated in asthma, urticaria (hives), or any other allergic reactions to taking aspirin or an NSAID.
- If you have peptic ulcer disease or any active gastric bleeding. This medicine is contraindicated.
- If you have active bleeding anywhere in the body (cerebrovascular, etc.). This medicine is contraindicated.
- If you need medication for pain management associated with heart bypass surgery (CABG, or Coronary Artery Bypass Grafting). This medicine is contraindicated.
- If you have been diagnosed with heart failure and oedema. This medicine is contraindicated.
- If you have been diagnosed with liver and kidney failure. This medicine is contraindicated.
- If you have decreased haemoglobin levels or established anaemia. Avoid this medication.
- If you have infertility issues. This medicine by itself can cause reversible infertility.
Side effects
- Abdominal pain
- Loose stools
- Indigestion, burning sensation, pain on eating/drinking (dyspepsia)
- Nausea
- Flatulence
- Gastritis
- Vomiting
- Constipation
- Headache
- Dizziness
- Derangement of liver function test levels
- Decrease in haematocrit levels/anaemia
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You take other medications. Please inform your doctor at the time of prescription of Misogesic SR so they can be checked for interaction issues.
- You are pregnant or planning to conceive shortly. Inform your doctor at the time of prescription.
Directions for Use
- Take this medication as prescribed by your doctor.
- Swallow this medication whole. Do not crush, break, or chew this tablet.
- Take this medication for the entire duration recommended by your doctor.
- It is beneficial to take it on a regular schedule.
- Abruptly stopping this medication can cause a recurrence of symptoms.
- Take this medication with food to decrease gastric side effects.
- Do not mix this medication with alcohol.
- Inform your doctor regarding other medications you may be taking to review and prevent any medicine interaction associated effects.
Storage and disposal
Store below 25 degrees Celsius. Keep away from direct sunlight and moisture. Keep away from the reach of children and pets. Dispose of this medication responsibly as biomedical waste. Do not flush it down the toilet.
Dosage
Overdose
The effects of Diclofenac poisoning can include gastrointestinal issues, headache, drowsiness, confusion, dizziness, ringing sensation in the ears (tinnitus), loss of consciousness, seizures, and coma. It can also cause significant kidney and liver failure.
Misoprostol overdose can cause sedation, seizures, difficulty breathing, loose stools, fever, heart palpitations, and a fall in BP and heart rate.
In case of a suspected overdose, rush the affected person to a tertiary care hospital with ICU facilities for monitoring and further management.
Missed a Dose
If you miss a dose of Misogesic SR tablet, take the tablet as soon as you remember. If the duration lapsed is long, and it is almost time for the next dose, skip the missed dose and return to your regular schedule. Do not double the dose of this medication.
Mode of Action
How Does It Work?
The active components of Misogesic SR tablets are Diclofenac and Misoprostol.
Diclofenac is a potent NSAID (non-steroidal anti-inflammatory drug). It works by blocking enzymes that affect the production of substances that mediate inflammation and pain sensation. It is particularly effective in blocking the activity of these enzymes in joints, thereby its efficacy in managing pain in conditions like osteoarthritis and rheumatoid arthritis. Diclofenac decreases inflammation, swelling, and pain in affected joints. However, it can affect the stomach's protective lining, resulting in irritation and even ulcer formation. Misoprostol is added to diclofenac in Misogesic SR tablets to prevent ulcer formation.
Misoprostol is a prostaglandin analogue. Prostaglandins are chemical substances that enhance the protective lining of the stomach and small intestine. Hence, misoprostol helps in decreasing the irritant side effects of the painkiller.
Interactions
Interactions with other medicines
- Misogesic SR tablets can affect the balance of bleeding and clotting (haemostasis). They should not be taken with other medicines that can affect haemostasis like warfarin, antidepressants like SSRIs, SNRIS, etc.
- This medication can decrease the efficacy of tablets used to lower blood pressure and should be mixed. These anti-hypertensives include ACE Inhibitors, ARBs, and beta-blockers. It can also cause renal impairment when combined with these medications.
- Diuretics are medicines that promote urination and excretion of salts from the body. This medication can decrease the effects of diuretic medication.
- The concomitant use with Digoxin is not recommended as it can prolong the effects of Digoxin, which may lead to toxicity.
Interactions with food items
- Misogesic SR does not have any specific food interactions.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:MISOGESIC
Country of Origin:India
Vendor Details
Fulfillment Information: Misogesic Sr Strip Of 10 Tabletss will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- ARTHROTEC (diclofenac sodium and misoprostol tablets), for oral use [Internet] [cited 20 March 2022]
- Arthrotec 50 modified-release Tablets: Summary of Product Characteristics (SmPC) - (emc) [Internet]. medicines.org.uk. 2022 [cited 20 March 2022]
- Alfaro RA, Davis DD. Diclofenac [updated 2021, Jun 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [cited 20 March 2022]
- Krugh M, Maani CV. Misoprostol. [Updated 2021, Jul 13]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [cited 20 March 2022]
- New Drugs Approved by CDSCO [Internet] [cited 20 Mar 2022]
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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
