Losakind H Strip Of 10 Tablets

• If you are allergic to losartan, hydrochhlorothiazide or any of the ingredients of Losakind H Tablet.
• If you are allergic to sulfonamide medicines such as co-trimoxazole.
• If you have a low level of potassium & sodium or high levels of calcium in your blood.
• If you have serious liver disorders and problems related to bile duct (canal connecting liver to intestine) like cholestasis.
• If you have kidney disease due to which you are not producing enough urine.
• If you have diabetes or kidney problem and taking a medicine for high blood pressure like Aliskiren.
• If you have gout.
• If you are pregnant for more than 3 months.

• Cough, nasal congestion and sinusitis
• Nausea, diarrhoea, stomach pain and indigestion
• Chest pain and tiredness
• Muscle pain, back pain and pain in the legs
• Headache, weakness, dizziness and sleeplessness
• Kidney and liver dysfunction
• Low blood sugar levels

Other General Warnings

• You have a history of swelling of the face, lips, throat or tongue due to water retention.
• You have blocked arteries of your kidneys or recently had a kidney transplant or have only one functioning kidney.
• You experience fainting and giddiness, especially after the first dose.
• You are planning a pregnancy, this medicine will be changed.
• You are facing problems with liver function and related organs-like cholestasis and biliary obstructive.
• Your kidneys are not functioning correctly or you have underlying kidney disease like renal artery stenosis (Narrow kidney blood vessels).
• You have been experiencing fluid losses within your body due to diarrhoea, vomiting, etc.
• You have serious heart valve-related problems like congestive heart failure, aortic or mitral stenosis and ischaemic cardiopathy.
• You are suffering from primary aldosteronism (a condition of excess production of the hormone aldosterone from the adrenal glands).
• You have diabetes as this medicine may affect your blood glucose levels, glucose monitoring is needed.
• You have an electrolyte imbalance of sodium, magnesium, potassium and have symptoms of dryness of mouth, thirst, drowsiness, muscle pain, nausea, vomiting, etc.
• You have galactose intolerance (small intestine's inability to transport and absorb glucose and galactose).
• You develop eye pain and a decrease in vision.
• You had any skin cancer or developed any skin lesions.
• You have gout, diabetes, bronchial asthma or any autoimmune diseases like systemic lupus erythematosus.

• Losakind H Tablet should be consumed as a whole with a sufficient amount of water with or without food.
• Do not change your dose unless your doctor tells you to do. Never stop this medicine on your own.
• This medicine tends to catch moisture and should be taken out from the blister just before use.

• Store this medicine below 30°C.
• Keep this medicine in the original container to protect it from light and moisture.

Overdose

Missed a Dose

• It would be best if you never miss a dose of your blood pressure medicine as it may lead to serious high blood pressure-related problems.
• If you missed any dose, take it as soon as you remember.
• If it is time for the next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose of this medicine to compensate for the missed one.

How Does It Work?

• Losartan lowers the blood pressure by blocking the action of a hormone called angiotensin responsible for narrowing of blood vessels and rise in blood pressure.
• Hydrochlorothiazide acts by increasing the production of urine and loss of water and salt from body, thereby lowering the blood pressure. Both the medicines act by different mechanisms resulting in effective control of blood pressure.

Interactions with other medicines

• Your blood potassium levels may go down if you are taking steroids, antifungals like Amphotericin.
• Medicines used to treat depression or other mental conditions like Lithium, Thioridazine and Chlorpromazine.
• Your blood potassium levels may increase if you are taking potassium supplements (Amiloride, Spironolactone) and Trimethoprim.
• You may experience low blood sugar if you are taking medicine for diabetes like Insulin and Metformin along with this medicine (severe kidney problems may also arise with Metformin).
• This medicine can decrease your blood pressure abruptly if taken with other blood pressure-lowering medicine.
• Your blood cell production may be hampered if you take this with medicines like Cyclophosphamide and Methotrexate.
• Medicines used to treat pain and inflammation like Aspirin, Ibuprofen and Naproxen interferes with the way this medicine works
• You may experience anaemia if you are taking medicine like Methyldopa.
• Concomitant use of Cyclosporin may increase the risk of gout.
• You may experience abnormal heart rhythms if you are taking medicine for heart failure like Digoxin.
• Medicines that may not be able to work properly due to increased potassium levels are used to treat irregular heartbeats like Quinidine, Sotalol and Amiodarone.
• This medicine can increase blood calcium levels if you are taking vitamin D and calcium supplements.
• Other medicines like Probenecid, Allopurinol, Atropine, Biperiden and muscle relaxants like Tubocurarine, Cholestyramine and Colestipol.

Interactions with food items