Jakavi 5Mg Strip Of 10 Tablets

• Myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis.
• Polycythemia vera in patients who are resistant to or cannot tolerate hydroxyurea.
• Acute graft-versus-host disease (GvHD) in adults and children aged 12 years and older who have been previously treated unsuccessfully with steroid medications.

• Anaemia (low red blood cell count)
• Thrombocytopenia (low platelet count)
• Neutropenia (low neutrophil count)
• Infections, including urinary tract infections and herpes zoster
• Headache
• Dizziness
• Bruising and bleeding
• Increased cholesterol or triglyceride levels
• Weight gain
• Constipation
• Nausea
• Increased liver enzymes
• Increased blood creatinine
• Increased creatine phosphokinase (CPK)

• Serious infections, including tuberculosis, hepatitis B reactivation, herpes zoster, and sepsis
• Serious bleeding, particularly when blood platelet counts are low
• Thrombosis, including venous thromboembolism
• Progressive multifocal leukoencephalopathy (PML), a rare serious brain infection
• Non-melanoma skin cancers
• Major cardiovascular events, particularly in patients with cardiovascular risk factors
• Severe allergic reactions

Other General Warnings

• You have low blood cell counts or develop signs of infection.
• You have a serious infection, tuberculosis, or hepatitis B.
• You develop symptoms of shingles.
• You develop new memory, neurological, or mental health changes.
• You have high cholesterol or triglyceride levels.
• You are 65 years or older, or are a current or former long-term smoker.
• You have heart disease or risk factors for blood clots.
• You develop leg swelling or pain, chest pain, or shortness of breath.
• You have a history of skin cancer or precancerous skin lesions; regular skin checks may be recommended.
• You have kidney or liver problems, as your dose may need adjustment.
• Your symptoms return or worsen after stopping or interrupting Jakavi tablet.

• Jakavi tablet should be taken orally, with or without food, as prescribed by your doctor.
• Take the medicine at approximately the same time each day. Do not change the dose or stop treatment without consulting your doctor.

• Store the medicine as directed on the product label.
• Keep Jakavi tablet out of the reach of children.

Overdose

Missed a Dose

• If you miss a dose, skip it and take the next usual dose at the scheduled time.
• Do not take an extra dose to make up for the missed dose

Interactions with other medicines

• CYP3A4 inhibitors: Medicines such as ketoconazole, clarithromycin, and erythromycin may increase ruxolitinib levels and the risk of side effects. Your doctor may adjust the dose.
• CYP3A4 inducers: Medicines such as rifampicin, carbamazepine, and phenytoin may lower ruxolitinib levels and reduce its effectiveness.
• Tell your doctor if you take antibiotics or antifungal medicines, as some may interact with ruxolitinib.
• Always inform your doctor about all medicines, supplements, and herbal products you take.