Esta Plus Tablets

10 Tablet(s) in Strip
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Esta Plus Tablets Description

Esta plus tab is a combination medication of two active ingredients, clonazepam and escitalopram. It belongs to a group of medicines used to treat psychiatric disorders like clinical depression and ...
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Product Summary

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UsesDepression, anxiety, bipolar disorder
Side effectsConfusion, dizziness, seizures, sleep disturbances, sexual dysfunction
Check more medicines with composition as Clonazepam + Escitalopram

Uses of Esta Plus Tablets

  • Esta plus is used in the treatment of clinical depression and anxiety-related disorders. It is also used for the treatment of panic disorders and bipolar disorder.

Contraindications of Esta Plus Tablets

Esta plus tab is not given to patients/given with caution in: Allergy to clonazepam and escitalopram Presence/history of seizures as it may carry the risk of recurrent seizures while taking this med...
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Side effects of Esta Plus Tablets

  • Esta plus may cause side effects like
  • Common:
  • Rapid heart rate
  • Dizziness fatigue
  • Confusion
  • Seizure, uncontrolled muscle movements
  • Reduced urination, urinary retention
  • Less common:
  • Nervousness
  • Dry mouth
  • Sleep problems
  • Decreased sexual interest

Precautions and Warnings of Esta Plus Tablets


Can I take an Esta plus tab during pregnancy?
No, it is not advised to take Esta plus tablets during pregnancy as limited human data trials have shown harmful effects on the fetus. Please consult your physician if you are pregnant or planning a pregnancy while on this medication.

Breast Feeding

Can I take an Esta plus tab while breastfeeding?
No, it is not advised to take Esta plus tab while you are breastfeeding as studies have shown that the medication passes into breast milk and can lead to certain side effects on the baby like tremors, sleep problems, excessive crying.


Can I drive if I have taken the Esta plus tab?
No, it is not advised to drive or operate any kind of heavy machinery when you have taken Esta plus tab due to its tendency to cause side effects like dizziness, tiredness, confused thinking, and seizures.


Can I consume alcohol with the Esta plus tab?
No, it is not advised to consume alcohol while you are taking Esta plus tablets as it can increase the severity of side effects like confusion, muscle tremors, seizures, and sleep problems.

Other General Warnings

Talk to your doctor if
  • Talk to your doctor if :
  • You experience persistent side effects, and they seem to worsen over time.
  • You want to stop taking Esta plus tab.
  • You do not see any progress from the use of Esta plus.
  • You develop an allergy to Esta plus tab (rashes, hives, swelling on the hands or face).
  • You have missed a dose or doses of the medication.
  • You experience any other medical issues that arise after you start taking Esta plus.

Mode of Action of Esta Plus Tablets

How Does It Work?

Esta plus tab is used to treat depression and anxiety disorders. It helps in elevating the mood, removing sadness, anger, and nervousness. It has two active ingredients in it, clonazepam and escita...
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Directions for Use of Esta Plus Tablets

  • Esta plus comes in a strip of 10 tablets. It has to be taken orally along with water with/without food.
  • The time of the dose is prescribed by the physician, and it is usually advised to take medicine at the same time every day.
  • Do not chew or crush the tablet into powder form.
  • It is advised to check the expiry date before you start the medication.
  • Please inform your doctor in case of any missed doses/doses.
  • Do not change or increase/decrease the dose without speaking to your physician.
  • Stopping Esta plus tab abruptly, especially after prolonged use, can cause withdrawal symptoms like sleep disturbances, fatigue, and increased tendency of seizures.

Interactions of Esta Plus Tablets

Interactions with other medicines

  • Esta plus should not be given along with/given with caution if you are on:
  • NSAIDs/painkillers like Aspirin as it may increase the risk of bleeding episodes.
  • Esta plus tab, when taken along with monoamine oxidase inhibitors like isocarboxazid, phenelzine, selegiline, can lead to an increased risk of serotonin syndrome; therefore, a 14 days gap is advised b...
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  • When taken along with anti-anxiety medicines like Buspirone, it can cause complications like excess sweating, nervousness, insomnia, increased heart rate, and agitation.
  • Taking it along with pain medications like tramadol, sumatriptan, and rizatriptan can reduce the efficacy of Esta plus tab.
  • Antifungals like ketoconazole and itraconazole and antivirals like ritonavir can increase levels of clonazepam in the blood.
  • Esta plus should not be taken along with other benzodiazepines (antidepressants) like carbamazepine, phenytoin as they can cause breathing issues when taken together.
  • Medications that cause drowsiness should not be prescribed along with Esta plus like Opioids (codeine), anti-allergy (cetirizine), painkillers like morphine, and sleep medications like Zolpidem.

Interactions with food items

  • Esta plus tab does not show adverse reactions to any food. It is not advised to consume alcohol while on therapy with Esta plus tab as it may increase the severity of side effects like dizziness, fati...
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Storage and disposal of Esta Plus Tablets

Esta plus tab comes in a box containing a strip of 10 tablets. It is to be stored around 25° celsius or at room temperature. It should be kept away from children and pets at home. Esta plus tab should...
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Dosage of Esta Plus Tablets


  • Overdose of Esta plus tablets can be accidental due to missed doses, improper dosage, or intentional overuse.
  • Overdose of Esta plus tablets can cause confusion, seizures, and uncontrolled muscle movements. It can cause serotonin syndrome (shivering, muscle stiffness, rapid heart rate, and fever), which happen...
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  • All patients on Esta plus tablets should be regularly monitored.
  • Any cases of overdose of Esta plus tablets should be immediately reported to the emergency unit of your nearest healthcare provider.

Missed a Dose

If you miss a dose of Esta plus tablets, you can take the missed dose as soon as you realise that you have missed the dose. If the next scheduled dose is only a few hours away, then it is advised not ...
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Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: When will Esta plus tab start working for me?

A: Like most psychiatric medications, Esta plus tablets require up to 2 to 6 weeks to show their full benefits from the start of the medication. It is advised to consult your physician if you feel the medication does not seem to work for you, even after taking the prescribed dose.

Q: Can I consume coffee while I am on the Esta plus tab?

  • Caffeine does not seem to interfere with the efficacy of Esta plus tablets; therefore, consuming coffee is allowed within dietary limits.
Product Details
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Last Updated on: 01 Mar 2022 | 11:50 AM (IST)

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