Esta Plus Tablets
10 Tablet(s) in StripWe do not sell this product
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Dosage
TABLET
Expiry
Product Summary
| Salt Content | Escitalopram(10.0 Mg)+Clonazepam(0.5 Mg) |
| Uses | Depression, anxiety, bipolar disorder |
| Therapy | Anti-anxiety and anti-depressant |
| Side effects | Confusion, dizziness, seizures, sleep disturbances, sexual dysfunction |
Assurance
available
Regulated
Medical Description
Esta plus tab is a combination medication of two active ingredients, clonazepam and escitalopram.
It belongs to a group of medicines used to treat psychiatric disorders like clinical depression and anxiety disorders.
Depression is a condition causing emotional and physical problems that may lead to feelings of sadness and loss of interest in the activities that were once enjoyed. It also causes difficulty in sleeping, anger, and loss of energy.
Esta plus brings about certain changes in the chemical messengers in the brain leading to a reduction in abnormal activity in the nerve cells, thus making the patient calmer and less anxious. It also increases the levels of hormones/chemical messengers (Serotonin) in your brain tissues that are responsible for the elevation of mood and happy feelings.
Esta plus tablets can be taken orally with water with/without food. It is not recommended for patients below the age of 18. Esta plus can cause side effects like rapid heart rate, dizziness, confusion, and seizures.
Esta plus tab carries the risk of forming dependency habits and sexual dysfunction after prolonged use.
Stopping it abruptly causes withdrawal symptoms like confusion, sleep problems, and uncontrolled muscle movements.
Uses
- Esta plus is used in the treatment of clinical depression and anxiety-related disorders. It is also used for the treatment of panic disorders and bipolar disorder.
Contraindications
Esta plus tab is not given to patients/given with caution in:
Allergy to clonazepam and escitalopram
Presence/history of seizures as it may carry the risk of recurrent seizures while taking this medication
Liver disease
Kidney disease
Heart problems
Diabetes
Bleeding problems
Closed-angle glaucoma (increased intra eye pressure due to the drainage obstruction caused by the angle between iris and retina)
Esta plus must be taken with caution in patients with existing respiratory diseases as it may worsen the condition
Alcohol or substance addiction
Children and adolescents under 18 years of age
Side effects
- Esta plus may cause side effects like
- Common:
- Rapid heart rate
- Dizziness fatigue
- Confusion
- Seizure, uncontrolled muscle movements
- Reduced urination, urinary retention
- Less common:
- Nervousness
- Dry mouth
- Sleep problems
- Decreased sexual interest
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- Talk to your doctor if :
- You experience persistent side effects, and they seem to worsen over time.
- You want to stop taking Esta plus tab.
- You do not see any progress from the use of Esta plus.
- You develop an allergy to Esta plus tab (rashes, hives, swelling on the hands or face).
- You have missed a dose or doses of the medication.
- You experience any other medical issues that arise after you start taking Esta plus.
Directions for Use
- Esta plus comes in a strip of 10 tablets. It has to be taken orally along with water with/without food.
- The time of the dose is prescribed by the physician, and it is usually advised to take medicine at the same time every day.
- Do not chew or crush the tablet into powder form.
- It is advised to check the expiry date before you start the medication.
- Please inform your doctor in case of any missed doses/doses.
- Do not change or increase/decrease the dose without speaking to your physician.
- Stopping Esta plus tab abruptly, especially after prolonged use, can cause withdrawal symptoms like sleep disturbances, fatigue, and increased tendency of seizures.
Storage and disposal
Esta plus tab comes in a box containing a strip of 10 tablets. It is to be stored around 25° celsius or at room temperature. It should be kept away from children and pets at home. Esta plus tab should always be disposed of with medical waste. Any unused Esta plus tab should not be drained away in sinks or washrooms. Unused medication should not be thrown away in other household waste.
Dosage
Overdose
- Overdose of Esta plus tablets can be accidental due to missed doses, improper dosage, or intentional overuse.
- Overdose of Esta plus tablets can cause confusion, seizures, and uncontrolled muscle movements. It can cause serotonin syndrome (shivering, muscle stiffness, rapid heart rate, and fever), which happens due to excess accumulation of serotonin in the body. If not handled properly, it can lead to coma or be fatal.
- All patients on Esta plus tablets should be regularly monitored.
- Any cases of overdose of Esta plus tablets should be immediately reported to the emergency unit of your nearest healthcare provider.
Missed a Dose
If you miss a dose of Esta plus tablets, you can take the missed dose as soon as you realise that you have missed the dose. If the next scheduled dose is only a few hours away, then it is advised not to take the missed dose and directly take the next scheduled dose and then continue as usual. Do not double your dose without consulting your physician.
Mode of Action
How Does It Work?
Esta plus tab is used to treat depression and anxiety disorders. It helps in elevating the mood, removing sadness, anger, and nervousness.
It has two active ingredients in it, clonazepam and escitalopram. Escitalopram belongs to a class of medicines known as Selective Serotonin Uptake Inhibitors (SSRI). It acts by increasing the levels of a mood-elevating hormone in the brain called serotonin.
The other active ingredient, clonazepam, belongs to the benzodiazepines group of medicines. It facilitates the transmission of a chemical in the brain called GABA (Gamma Amino Butyric Acid). This helps in decreasing the excessive nerve activity in the brain, thereby producing a calming effect on the mind. Thus in combination, they act by improving the mood, behaviour, and life responses of a patient.
Interactions
Interactions with other medicines
- Esta plus should not be given along with/given with caution if you are on:
- NSAIDs/painkillers like Aspirin as it may increase the risk of bleeding episodes.
- Esta plus tab, when taken along with monoamine oxidase inhibitors like isocarboxazid, phenelzine, selegiline, can lead to an increased risk of serotonin syndrome; therefore, a 14 days gap is advised between stopping one medicine and starting the other.
- When taken along with anti-anxiety medicines like Buspirone, it can cause complications like excess sweating, nervousness, insomnia, increased heart rate, and agitation.
- Taking it along with pain medications like tramadol, sumatriptan, and rizatriptan can reduce the efficacy of Esta plus tab.
- Antifungals like ketoconazole and itraconazole and antivirals like ritonavir can increase levels of clonazepam in the blood.
- Esta plus should not be taken along with other benzodiazepines (antidepressants) like carbamazepine, phenytoin as they can cause breathing issues when taken together.
- Medications that cause drowsiness should not be prescribed along with Esta plus like Opioids (codeine), anti-allergy (cetirizine), painkillers like morphine, and sleep medications like Zolpidem.
Interactions with food items
- Esta plus tab does not show adverse reactions to any food. It is not advised to consume alcohol while on therapy with Esta plus tab as it may increase the severity of side effects like dizziness, fatigue, and clouded thinking.
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Manufacturer Details
Brand:ESTA
Vendor Details
Fulfillment Information: Esta Plus Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Clonazepam: Bullous dermatosis in an elderly patient: case report. (2013). Reactions Weekly, 1440(1), 13–13
- Clonazepam (Klonopin). (n.d.). Nami.Org. Retrieved February 21, 2022, from
- Escitalopram: Galactorrhoea: case report. (2014). Reactions Weekly, 1526(1), 60–60.
- Rosa, T. F. da, Machado, C. de S., Serafin, M. B., Bottega, A., Coelho, S. S., Foletto, V. S., Rampelotto, R. F., Lorenzoni, V. V., Mainardi, A., & Hörner, R. (2021). Repurposing of escitalopram oxalate and clonazepam in combination with ciprofloxacin and sulfamethoxazole-trimethoprim for treatment of multidrug-resistant microorganisms and evaluation of the cleavage capacity of plasmid DNA. Canadian Journal of Microbiology, 67(8), 599–612.
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
