Decapeptyl 95.600Laciu Pf

• Palliative treatment of advanced hormone-dependent prostate cancer in adult males.
• Treatment of endometriosis and uterine fibroids in women.
• Pituitary desensitization for assisted reproductive techniques (ART) in women.

• If you have a known hypersensitivity or severe allergic reaction to triptorelin, other GnRH analogues, or any of the inactive ingredients.
• If you are pregnant or breastfeeding.
• If the specific formulation is contraindicated in your clinical condition, as determined by your doctor.
• If you have undiagnosed abnormal vaginal bleeding.

• Hot flushes and excessive sweating
• Decreased libido and impotence (in men)
• Fatigue, weakness, and headache
• Mood changes and emotional lability
• Injection site reactions (pain, redness, or swelling)

• Weight gain and increased appetite
• Joint pain (arthralgia) and muscle pain (myalgia)
• Gastrointestinal disturbances such as nausea or abdominal pain
• Sleep disturbances (insomnia)
• Breast tenderness or enlargement (in men)

• Temporary tumour flare (worsening of bone pain or urinary symptoms during the first few weeks of prostate cancer treatment)
• Spinal cord compression or urinary tract obstruction may occur in patients with advanced prostate cancer, particularly during tumour flare
• Decreased bone mineral density (increased risk of osteoporosis or bone fractures)
• Cardiovascular changes or risk of glucose tolerance alterations (diabetes)
• Severe hypersensitivity or allergic reactions

Other General Warnings

• You experience a sudden increase in bone pain, urinary difficulties, or weakness in your legs during the first few weeks of treatment if you are being treated for advanced prostate cancer, as these may indicate tumour flare or its complications.
• You have a history of cardiovascular disease, diabetes, or depression, as close monitoring is necessary.
• You notice signs of bone weakening, such as back pain or unexplained bone fractures over time.
• You develop signs of a severe allergic reaction, such as a rash, itching, or breathing difficulties, after an injection.

• Administer Decapeptyl injection strictly as a subcutaneous or intramuscular injection, exactly as prescribed by your doctor.
• Follow your healthcare provider's instructions carefully regarding the specific dosing frequency, whether daily or via long-acting depot formulations.
• Use proper aseptic technique during injection.
• Keep all scheduled appointments for your injections and clinical check-ups.

• Store the vials or pre-filled syringes according to the specific manufacturer instructions (often at room temperature or refrigerated, depending on the formulation).
• Keep the medication container in its original outer carton to protect it from light.
• Keep out of the reach of children and pets.
• Ask your pharmacist or healthcare provider about the proper disposal of used syringes, needles, and expired medication.

• Keep all scheduled doctor appointments to monitor your hormone levels, bone density, and overall response to treatment.
• Report any sudden worsening of bone pain, difficulty urinating, or neurological symptoms during the first few weeks of therapy immediately.
• Stay physically active and maintain a healthy diet to help manage weight gain and support your bone health.
• Inform your healthcare providers that you are taking this medication before undergoing any other medical evaluations or surgeries.
• Use appropriate skin care at the injection site to minimize local discomfort.

Overdose

Missed a Dose

Interactions with other medicines

• Inform your doctor about all prescription drugs, over-the-counter medications, and herbal supplements you are taking, especially treatments for diabetes or cardiovascular conditions.
• Concomitant use with drugs that affect blood glucose levels may require adjustments in your medication, as triptorelin can influence glucose tolerance.
• Use caution with medications that affect bone density.
• Tell your doctor if you are taking medicines known to prolong the QT interval, as some GnRH agonist treatments may increase the risk of abnormal heart rhythms.

Interactions with food items

• No specific food restrictions are required, as the medication is administered via injection.
• Maintain a balanced diet rich in calcium and vitamin D to help support bone health during long-term hormone suppression therapy.
• Avoid excessive alcohol consumption, as it can worsen fatigue, hot flushes, mood changes, and place extra strain on your overall well-being.