Crikzo 250Mg Bottle Of 30 Capsules

• Visual disturbances (such as flashes of light, blurred vision, or increased sensitivity to light)
• Gastrointestinal disturbances (nausea, diarrhea, vomiting, constipation, and decreased appetite)
• Edema (swelling, particularly in the hands, ankles, or feet)
• Fatigue and asthenia (weakness)
• Elevated liver enzymes (transaminases)
• Dizziness and neuropathy (numbness or tingling)

• Taste disturbances (dysgeusia)
• Rash and dry skin
• Low white blood cell counts (neutropenia) or anemia
• Joint pain (arthralgia)
• Bradycardia (slow heart rate)
• Photosensitivity

• Serious heart rhythm problems, including changes in the QT interval.
• Serious lung problems, such as interstitial lung disease or pneumonitis.
• Severe liver problems, including liver failure.
• Severe or persistent vision problems, including vision loss.
• Kidney problems, including kidney cysts or reduced kidney function.
• Heart failure.
• A hole or tear in the stomach or intestine (gastrointestinal perforation)

Other General Warnings

• You experience sudden shortness of breath, a dry cough, or breathing difficulties, which may indicate pneumonitis.
• You notice yellowing of the skin or eyes, dark urine, or upper abdominal pain (signs of liver strain).
• You notice persistent changes in your vision.
• You develop a very slow heartbeat, particularly with dizziness, fainting, or low blood pressure.
• You have a history of heart disease, QT prolongation, electrolyte abnormalities, or are taking medicines that affect heart rhythm.
• You develop severe abdominal pain, particularly with fever or other symptoms of gastrointestinal complications.

• Take Crikzo capsule orally exactly as your doctor prescribed.
• Swallow the capsules whole with a glass of water; do not crush, chew, open, or dissolve them.
• You may take this medication either with or without food.
• Continue your treatment course as long as you observe clinical benefit or until your doctor advises discontinuation. Never alter your dose without consulting your physician.

• Store the capsules according to the product label
• Keep out of the reach of children and pets in a secure medical environment.
• Return any unused or expired capsules to your pharmacist for safe disposal.

• Be cautious when driving or operating machinery at night, as crizotinib frequently causes visual disturbances like bright flashes of light.
• Keep all scheduled blood tests, liver-function assessments, ECGs, and other monitoring appointments.
• Report any new or worsening cough, shortness of breath, or chest pain to your doctor immediately, as lung inflammation requires urgent care.
• Report severe or persistent changes in vision promptly.
• Tell your healthcare providers you are taking this medication before any other medical procedures or eye examinations.
• Stay well hydrated, and tell your doctor early if you experience persistent nausea or diarrhea.

Overdose

• If an overdose is suspected, contact your doctor immediately or seek emergency medical care. There is no specific antidote.
• Treatment focuses on managing symptoms and close medical monitoring.

Missed a Dose

• If you miss a dose of Crikzo capsule, take it as soon as you remember, unless it is less than 6 hours until your next scheduled dose.
• If so, skip the missed dose and take your next dose at the usual time.Do not take two doses at the same time to make up for

Interactions with other medicines

• Ketoconazole, clarithromycin, and ritonavir may increase crizotinib levels and the risk of side effects.
• Rifampicin, carbamazepine, and St. John’s wort may reduce crizotinib levels and make it less effective.
• Tell your doctor if you take medicines that can affect heart rhythm or slow your heartbeat, as crizotinib can also affect heart rhythm.
• Some medicines with a narrow safety range may interact with crizotinib and require careful monitoring.
• Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, supplements, and herbal products you take.

Interactions with food items

• Crizotinib can generally be taken with or without food.
• Avoid grapefruit, grapefruit juice, and products containing grapefruit extract while taking crizotinib, as they may increase the amount of crizotinib in your blood and increase the risk of side effects.