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Combunex 800mg Tablet

10 Tablet(s) in Strip
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Combunex 800mg Tablet Description

Combunex 800 mg Tablets is used to treat and prevent tuberculosis. The Combunex 800 mg tablets are effective against treating bacterial infections caused by tubercular bacilli. Combunex 800 mg is com

posed of Isoniazid and Ethambutol. Tuberculosis is an infectious disease caused by mycobacterium tuberculi that affects the lungs. Collectively, uses of Combunex tablets include eliminating the infection, preventing the growth of bacteria and killing them. Combunex 800 mg tablet should be taken as prescribed by the doctor. In most circumstances, serious adverse effects are uncommon. Drink plenty of water to minimise the side effects, if any. To know the food interactions of Combunex, talk to your doctor.


Product Summary

Offer Price₹81.30
You Save₹14.35 (15% on MRP)
ContainsIsoniazid(300.0 Mg) + Ethambutol(800.0 Mg)
Side effectsNausea, vomiting, fever rashes, sweating, salivation, numbness in fingers, visual impairment
Check more medicines with composition as Isoniazid(300.0 Mg) + Ethambutol(800.0 Mg)

Uses of Combunex 800mg Tablet

  • As per CDSCO, Combunex 800 mg is used for the treatment of Tuberculosis (TB)

Contraindications of Combunex 800mg Tablet

  • If you have a known allergy to Combunex 800 mg tablets.
  • If you have liver disease or are on medication for liver disease.
  • If you have porphyria - a condition where porphyrin (a substance that helps to make haemoglobin) accumulates in the body.
  • If you have HIV and are on HIV medications.
  • If you have epilepsy - a condition characterised by fits and seizures.
  • If you have gout - a disease where uric acid levels are high.
  • If you are suffering from malnutrition - where your body is not getting enough nutrition and lacking in macro as well as micronutrients.
  • If you have diabetes, kidney problems and peripheral neuropathy.

Side effects of Combunex 800mg Tablet

  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark coloured urine
  • Sweating

Precautions and Warnings of Combunex 800mg Tablet



Can I take Combunex during pregnancy?
No. It's possible that using the Combunex Tablets while pregnant is dangerous. Combunex Tablets should not be taken when pregnant since it may cause problems for both the mother and the baby after birth by disrupting the unborn baby's growth.

Breast Feeding

Can I take Combunex 800 mg while breastfeeding?
Combunex 800 mg tablets capsule traces are transmitted from mother to baby through breast milk. While using the Combunex 800 mg tablets capsules, do not breastfeed your baby without consulting your doctor. These tablets can only be used while breastfeeding if prescribed by a doctor.


Can I drive if I have taken Combunex 800 mg?
No. Side effects from the Combunex 800 mg tablets may impair your ability to drive. Dizziness, visual issues, numbness, and tingling sensations in the hands and feet are all possible side effects of the Combunex Tablets.


Can I consume alcohol with Combunex 800 mg?
No. Avoid drinking alcohol while taking a Combunex 800 mg tablets capsule because it might make you feel dizzy and damage your liver. Drinking alcohol while taking Combunex 800 mg tablets might cause flushing, rapid heartbeat, nausea, thirst, chest pain, and a drop in blood pressure.

Other General Warnings

Talk to your doctor if
  • You have skipped a dosage. Doing so increases the risk of bacteria developing resistance to the medication.
  • You found that you are pregnant. Combunex 800 mg tablets are known to make hormonal contraceptive pills less effective.
  • You need a prescription for children. You must not give Combunex 800 mg tablets to children.
  • You want to stop the medication. Early discontinuation of treatment increases the risk of infection recurrence.
  • Your blood sugar levels are high. Blood sugar can be affected by this medication. If you have diabetes, use Combunex 800 mg tablets with caution.
  • Your doctor may recommend vitamin B6 pills to prevent vitamin B6 deficiency.

Mode of Action of Combunex 800mg Tablet

How Does It Work?

Combunex 800 mg Tablet used in tuberculosis treatment is a combination of two medicines Isoniazid, and Ethambutol. Isoniazid prevents bacteria from forming their protective covering. Ethambutol operat...
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Directions for Use of Combunex 800mg Tablet

  • Follow the doctor's directions for Combunex 800 mg medication's dosage and duration.
  • Before using, double-check the label.
  • Take Combunex 800 mg tablets 30 minutes before or 2 hours after eating.
  • Take this tablet daily at a scheduled time to ensure better efficacy.
  • Instead of crushing, breaking or chewing the tablet's pill, take it with a glass of water.
  • Depending on the severity of the infection, the duration and dose of the Combunex Tablet may vary.

Interactions of Combunex 800mg Tablet

Interactions with other medicines

  • Antibiotic - Erythromycin
  • Antiepileptic - Carbamazepine, phenytoin, primidone
  • Painkiller - Acetaminophen
  • Antitubercular - Rifampicin, para aminosalicylic acid
  • Anti-diabetic - Insulin isophane
  • Anti-HIV - Stavudine, saquinavir, ritonavir
  • Antacids - Omeprazole (aluminium hydroxide)
  • These medicines can interact with Combunex and cause adverse reactions in the body. In some situations, these reactions can lead to emergency hospitalisation. Some medicines interact and reduces the e...
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Interactions with food items

  • Avoid food that is high in tyramine or histamine, such as cheese, smoked salmon, meats, soya, tuna and some types of alcohol, as these foods can interact with Combunex 800 mg Tablet.

Storage and disposal of Combunex 800mg Tablet

Keep the medications in a cold and dry location, away from hot appliances in a safe cabinet. Even if it hasn't expired, medicine that has altered colour, texture, or pills that cling together, or soft...
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Dosage of Combunex 800mg Tablet


Overdose signs and symptoms are noted in the case of higher dose consumption. Symptoms of overdose can be drowsiness, confusion, coordination problems and altered consciousness. In case you experience...
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Missed a Dose

If you forget to take a Combunex Tablet, take it as soon as possible. If your next dose is due, omit the missed dose and resume your regular dosage schedule. Unless your doctor advises it, do not incr...
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Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: Do Combunex 800 mg tablets affect the action of birth control pills?

A: Oral contraceptives may be less effective if you use the Combunex Tablet. This may result in an unwanted pregnancy. Instead, when taking Combunex Tablet, use a safer contraceptive method like condoms or IUDs. If you have any concerns, talk to your doctor; he or she may offer an alternative type of contraception.

Q: Is it okay if I stop taking Combunex 800 mg Tablet if I'm feeling fine?

A: No. Complete the course of medication provided to you, even if you start to feel better. It may worsen your infection and become difficult to treat. It may even lead to medicine-resistant tuberculosis, in which case the medicines you were taking for tuberculosis may no longer be effective.

Q: Is it possible for Combunex Tablet to produce urine discolouration?

A: Yes, Combunex 800 mg Tablet contains rifampicin, which can stain your teeth, sweat, urine, saliva, and tears for a short time (red, orange, or brown colour). This is a common but non-harmful side effect. Urine discolouration, on the other hand, could be a sign of liver disease. Consult your doctor if you experience discoloured urine, stomach pain, loss of appetite, jaundice, or yellowing of the skin or eyes.
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Last Updated on: 01 Mar 2022 | 09:01 PM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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