C Pram S Plus 0.25mg Tablets
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10 Tablet(s) in Strip
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C Pram S Plus 0.25mg Tablets Description
C Pram S Plus Tablet is used for the treatment of depression & anxiety disorders. Anxiety and other mood disorders affect how you feel. It is characterised by excessive, unrealistic worry and fear th
at can interfere with daily activities, and it is often accompanied by major depressive disorder. C Pram S Plus Tablet helps the relaxing mood by lowering the excess activity of nerves in the brain. It can also cause a sedation effect which relieves anxiety and improves sleep. C Pram S Plus Tablet contains Clonazepam and escitalopram as their active ingredient. C Pram S Plus Tablet should be taken in dosage and duration as advised by your doctor. Do not stop taking this medicine suddenly without consulting your doctor, as it can cause clinical worsening of your condition or may lead to withdrawal symptoms.
Product Summary
| Offer Price | ₹98.09 |
| You Save | ₹17.31 (15% on MRP) |
| Contains | Clonazepam + Escitalopram |
| Uses | Treatment of Anxiety Disorder and Depression |
| Side effects | Nausea, Increased sweating, Fatigue, Confusion, Drowsiness, Insomnia, Sexual dysfunction |
Check more medicines with composition as Clonazepam + Escitalopram
Uses of C Pram S Plus 0.25mg Tablets
- As per CDSCO and USFDA, C Pram S Plus Tablet is used in the treatment of Anxiety disorder and depression.
Contraindications of C Pram S Plus 0.25mg Tablets
- You are allergic to any of the components of the C Pram S Plus Tablet.
- You are taking Monoamine Oxidase Inhibitors (MAOIs) and antipsychotic medicine-pimozide.
- You are already using other anti-anxiety or sedative medications.
- You have acute angle glaucoma, which increases the fluid pressure in the eyes.
- You have liver or kidney disease.
- You have respiratory issues.
- You have a severe heart condition.
- You are pregnant and a lactating mother.
Side effects of C Pram S Plus 0.25mg Tablets
- Nausea
- Increased sweating
- Fatigue
- Confusion
- Drowsiness
- Insomnia
- Sexual dysfunction
Precautions and Warnings of C Pram S Plus 0.25mg Tablets
Pregnancy
Q:
Can I take a C Pram S Plus Tablet during pregnancy?
A:
C Pram S Plus Tablet is not recommended during pregnancy. Some research studies have shown harmful effects of the medicines on the developing foetus(baby). Pregnant women are advised to take this medicine only if it is recommended by their doctor. The doctor will weigh the benefits and potential risks before prescribing the medicine.
Breast Feeding
Q:
Can I take a C Pram S Plus Tablet while breastfeeding?
A:
C Pram S Plus Tablet is not recommended during breastfeeding. It gets excreted into breast milk and can affect the baby. Consult your doctor and discuss the potential risks and benefits of C Pram S Plus Tablet. Your doctor may advise you to discontinue breastfeeding or prescribe low doses if you continue breastfeeding.
Driving
Q:
Can I drive if I have taken the C Pram S Plus Tablet?
A:
C Pram S Plus Tablet may cause side effects that could affect your ability to drive. The tablet may decrease alertness, affect your vision and can cause dizziness, lethargy, lightheadedness. Do not drive if you are experiencing these side effects after taking this medicine.
Alcohol
Q:
Can I consume alcohol with the C Pram S Plus Tablet?
A:
No, do not consume alcohol with C Pram S Plus Tablet. It increases the severity of side effects like drowsiness, dizziness, blurred vision, lethargy, liver injury, etc. It also worsens the condition of the disease for which you are taking this tablet.
Other General Warnings
Talk to your doctor if
- You have any allergic reactions after taking the C Pram S Plus Tablet.
- You have any suicidal ideation or self-harming thoughts.
- You notice a sudden decrease or loss of vision.
- You experience any severe side effects persistently.
- Your symptoms do not improve, or there is worsening of your condition.
- You have trouble breathing or talking.
- You have any previous mild liver or kidney condition, this medicine may need a dose adjustment.
- You have withdrawal symptoms like agitation, nausea, tremor, sweating, and confusion.
Mode of Action of C Pram S Plus 0.25mg Tablets
How Does It Work?
C Pram S Plus Tablet is a combination medicine that contains Clonazepam (0.25 mg) and Escitalopram (10 mg). Clonazepam (a benzodiazepine) acts as a GABA-A receptor agonist. GABA stands for Gamma Amino Butyric Acid, and it is an inhibitory neurotransmitter. By binding to the GABA-A receptor, it enhances the inhibitory effects of GABA, resulting in sedative, anti-anxiety, and muscle relaxant properties.
Escitalopram is an antidepressant belonging to the Selective Serotonin Reuptake inhibitors (SSRIs) class of medicine. It works by preventing the reuptake of a chemical messenger called serotonin by the nerve cells, which results in an increased level of serotonin in the brain. Increased serotonin levels directly lead to improved mood and relieve anxiety and depression symptoms....
Directions for Use of C Pram S Plus 0.25mg Tablets
- Take the C Pram S Plus Tablet as per the doctor’s prescription.
- You can take this medicine with or without food or as prescribed.
- Take this medication on a regular schedule, preferably at the same time every day.
- Do not break/crush the tablet or chew this medicine; take it as a whole.
- Do not take this tablet with other meds; consult your doctor first.
- Don’t stop taking this medication in between, as it may lead to withdrawal side effects.
- Do not consume if the package has been opened.
- Don’t exceed the dosage, even if you cannot feel its effects.
Interactions of C Pram S Plus 0.25mg Tablets
Interactions with other medicines
- Tell your doctor and pharmacist what prescription and non-prescription medications, herbal products, vitamins and nutritional supplements you are taking or plan to take as there is a chance of medicine interaction. Many medicines can interact with C Pram S Plus Tablet, making it less effective or increasing side effects. This includes-...
- MAOI (monoamine oxidase inhibitors) like Selegiline, Rasagiline, Isocarboxazid, etc., is strictly contraindicated as it may cause serotonin syndrome. Serotonin syndrome can also be induced by antidepressants, triptans, fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines. These are also contraindicated....
- Interaction with metoprolol can lead to excessive bradycardia (slow heart rate).
- Interaction with antipsychotics (pimozide, haloperidol), tricyclic antidepressants and antihistamines can prolong QT interval.
- NSAIDs, Aspirin, and other medications which affect coagulation may interact and can increase the risk of bleeding.
- Azole antifungals, clarithromycin or CYP2C19 inhibitors (e.g., fluconazole, fluvoxamine, omeprazole) interaction may cause increased serum levels.
Interactions with food items
- Food doesn’t influence the effect of the C Pram S Plus Tablet. However, avoid consuming this medicine with cola drinks, chocolates and caffeine-containing food items as it can result in serotonin syndrome (characterised by high blood pressure, confusion, and muscle rigidity due to high levels of serotonin)....
Storage and disposal of C Pram S Plus 0.25mg Tablets
Store C Pram S Plus Tablet away from sunlight. Ensure it is at room temperature in a cool and dry area. Medication should be away from children and pet animals in a closed or locked cabinet. Keep the medicine within its original packaging.
Disposal - Do not flush medicines down into the toilet or throw them into the dustbin unless instructed to do so. Medicines disposed of in this manner may pollute or contaminate the environment. Properly dispose of this product when it is expired or no longer required....
Dosage of C Pram S Plus 0.25mg Tablets
Overdose
C Pram S Plus Tablet overdose can result in symptoms like irregular heartbeat, low blood pressure, slowing of heart rate, sleepiness, double vision, difficulty breathing, cardiac arrest, ECG changes (change in heart functioning), and coma. If you overdose on this medicine and experience any of these symptoms, immediately seek emergency medical treatment from a nearby hospital....
Missed a Dose
If you’ve missed a dose of the C Pram S Plus Tablet, take it as you remember. If it's already time to take the next scheduled dose, then take the next scheduled dose. Do not double doses as it can cause overdose side effects. Talk to your doctor if you have any confusion regarding this issue....
Content Details
WRITTEN BY
Dr. Zishan Ahmad
Final year MBBS Student
REVIEWED BY
Dr. Vijay Y
MBBS, MD in Clinical Pharmacology
Frequently Asked Questions (FAQs)
Q: Does suddenly stopping the consumption of C Pram S Plus Tablet lead to withdrawal symptoms?
A: Yes, suddenly stopping the consumption of C Pram S Plus Tablet causes withdrawal symptoms which includes agitation, nausea, tremor, confusion, diarrhoea, vomiting, and sweating. Consult your doctor before stopping the consumption of the C Pram S Plus Tablet, as doses need to be tapered slowly to avoid undesirable side effects.
Q: Is C Pram S Plus Tablet suitable for all age groups, especially children or the elderly?
A: Generally, C Pram S Plus Tablet is not recommended for children below ten years since the safety and efficacy of this medicine have not been established. Also, this medicine should be used with caution in elderly patients because they are more prone to hepatic and renal impairment.
Q: Does taking C Pram S Plus Tablet affect my sexual life?
A: C Pram S Plus Tablet can cause decreased sexual drive, problems getting an erection and ejaculating, difficulty achieving orgasm in women. These side effects usually pass on their own after a couple of weeks. However, if you experience these side effects persistently, then consult your doctor.
References
View All
- Drugs H. Escitalopram: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 25 February 2022]. Available from:
- Escitalopram: an antidepressant [Internet]. nhs.uk. 2022 [cited 25 February 2022]. Available from:
- Drugs H. Clonazepam: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 25 February 2022]. Available from:
- Clonazepam: medicine to control seizures or fits, muscle spasms and restless legs syndrome [Internet]. nhs.uk. 2022 [cited 25 February 2022]. Available from:
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 25 February 2022]. Available from:
- [Internet]. Accessdata.fda.gov. 2022 [cited 25 February 2022]. Available from:
- DailyMed - ESCITALOPRAM OXALATE tablet [Internet]. Dailymed.nlm.nih.gov. 2022 [cited 25 February 2022]. Available from:
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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