Amitril Plus Tablets
10 Tablet(s) in StripWe do not sell this product
Made by
MANEESH PHARMACEUTICALS LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Chlordiazepoxide(5.0 Mg)+Amitriptyline(12.5 Mg) |
| Uses | Depression along with anxiety |
| Therapy | Anti-depressant |
| Side effects | Nausea, Vomiting, Dizziness, Confusion, Gain in weight, Xerostomia (dryness in the mouth) |
Assurance
available
Regulated
Medical Description
Amitril Plus Tab is used to treat depression and anxiety. It belongs to the class of tricyclic antidepressants (TCA). The main components of Amitril Plus Tab are amitriptyline and chlordiazepoxide. In some cases, it is prescribed to prevent the symptoms associated with these diseases.
Directions for the use of the Amitril Plus Tab should be strictly followed. This medicine should be taken at the same time every day. Care should be taken to avoid both an overdose and skipped doses. Amitril Plus Tab is a prescription medicine and should never be taken without consultation with the doctor. It can interact with certain foods and should never be consumed with alcohol.
Some common side effects of Amitril Plus Tab include vomiting, nausea, xerostomia (dryness in the mouth), low sexual desires, etc. If the side effects cause problems or persist for long, it is best to consult a doctor.
Uses
- Amitril Plus Tabl is used to manage the following conditions:
- Treatment of depression
- Treatment of anxiety (associated with depression where the person is unable to speak, express themselves, or feel comfortable while in situations of sudden urgency or, some cases, activities of everyday lifestyle)
Contraindications
- Before starting treatment with an Amitril Plus Tab, inform your doctor if any of the following statements are true:
- If you have been diagnosed with obesity (excessive weight because of high concentration of fat deposits)
- If you have been diagnosed with Chronic Obstructive Pulmonary Disorder (COPD)
- If you have liver disease
- If you have been diagnosed with uncontrolled hypertension (high blood pressure)
- If you have been diagnosed with diabetes (increased blood sugar levels)
- If you have been diagnosed with arrhythmia (irregular heartbeat)
- If you have any other uncontrolled heart disease
- If you have been diagnosed with hyperthyroidism (increased thyroid levels)
Side effects
- The common side effects of Amitril Plus Tab are as follows:
- Nausea
- Vomiting
- Diarrhoea
- Xerostomia (dryness in the mouth)
- Weight gain
- Sleepiness
- Nervousness
- Confusion
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- Your side effects persist for longer than usual.
- You experience dizziness and nervousness.
- You are trying to conceive.
- You are lactating.
- You are a chronic alcohol user.
- You are taking other medicines.
- You are taking alternative medicine like herbal medicines or homoeopathy.
Directions for Use
- Swallow the tablet as a whole with water; do not chew or crush it.
- Do not take without consulting a doctor. Amitril Plus Tab is a prescription medicine.
- Do not skip or stop this medicine suddenly, even if you start feeling better.
- Take it at the same time every day.
- Take it with or without food, depending upon your doctor's instructions.
- Talk to your doctor if side effects persist, even though they usually go away after some time.
Storage and disposal
Store the medicine in its original packing. Keep the tablets away from moisture and out of direct sunlight. Keep away from children and pets. Exchange facilities with local pharmacists can be used to discard any old or expired medicines. After using the medicine, discard the packaging carefully.
Dosage
Overdose
Symptoms of an Amitril Plus Tab overdose include nausea, vomiting, confusion, and in extreme cases, coma. If you suspect an overdose or experience these symptoms, contact your doctor or visit the nearest hospital.
Always be mindful of the dosing schedule. Never consume more than the prescribed dose. If you have accidentally taken a double dose, consult your doctor.
Missed a Dose
In case of a missed dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose of this medication.
Mode of Action
How Does It Work?
Amitril Plus tab has two main components called amitriptyline and chlordiazepoxide. These components come under the class of tricyclic antidepressants (TCA). While the specific action of amitriptyline is not yet clear, it has been observed to work by reducing the absorption of serotonin and norepinephrine. These two chemicals are present in the brain and act as messengers to pass information to and from the brain.
When their work is done, i.e., the message has been passed, they are usually absorbed by the nerve cells present in the brain. But because of amitriptyline, their absorption is decreased. When it happens, they can be used again for passing the message. Using the same chemical again and again for message transfer is beneficial. All this causes mood relaxation and elevation.
Chlordiazepoxide belongs to the category of benzodiazepines. Benzodiazepines work in the hypothalamus region of the brain. There are two receptors, Gamma-aminobutyric acid (GABA) and Benzodiazepine receptors, present in this area. These receptors interact with each other and cause a decrease in ARAS activity.
ARAS-ascending reticular activating system is a combination of nuclei (cells) in the brain that controls the sleep and wake cycle and transitions in the body. When alprazolam binds to the GABA-subtype A receptors, the exaggerated response messages of the increased heart rate, fast breathing, and sweating to the body from the brain are decreased. Thereby making a person feel more calm, relaxed, and better.
Interactions
Interactions with other medicines
- To avoid adverse effects caused by medicine interaction, inform your doctor about all medicines and supplements (including herbal medicines and supplements, and multivitamins) you are currently taking. When Amitril plus Tab is taken along with the following medicines, it can have adverse reactions:
- Antibiotics - linezolid - for bacterial infections efficiency can reduce the effectiveness of both the treatments.
- Anticholinergic medicines (used in the treatment of breathing disorders) can cause difficulty in breathing or breathlessness.
- Medicines that contain sympathomimetic agents like phenylephrine and isoproterenol (used in heart emergencies) can interact with the Amitril Plus Tab and cause an abrupt heart rate that can lead to restlessness or breathing difficulties. In some cases, heart failures or sudden deaths have been reported.
- Antifungal medicines like fluconazole with Amitril plus Tab can increase the side effects.
- Anti-tubercular medicine like rifampicin interact with these medications and cause an elevation in depression and sedation.
Interactions with food items
- As Amitril Plus Tab causes an increase in weight, it is advised to eat a healthy diet rich in vitamins and minerals, including green leafy vegetables and low sugar content diets.
Frequently Asked Questions (FAQs)
Articles
View All
Chronic Condition Articles
View All
Did you find this helpful?
Explore More at Pharmeasy
Vendor Details
Fulfillment Information: Amitril Plus Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
