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Amitril Plus Tablets

10 Tablet(s) in Strip
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Amitril Plus Tablets Description

Amitril Plus Tab is used to treat depression and anxiety. It belongs to the class of tricyclic antidepressants (TCA). The main components of Amitril Plus Tab are amitriptyline and chlordiazepoxide. I

n some cases, it is prescribed to prevent the symptoms associated with these diseases. Directions for the use of the Amitril Plus Tab should be strictly followed. This medicine should be taken at the same time every day. Care should be taken to avoid both an overdose and skipped doses. Amitril Plus Tab is a prescription medicine and should never be taken without consultation with the doctor. It can interact with certain foods and should never be consumed with alcohol. Some common side effects of Amitril Plus Tab include vomiting, nausea, xerostomia (dryness in the mouth), low sexual desires, etc. If the side effects cause problems or persist for long, it is best to consult a doctor.


Product Summary

Offer Price₹26.06
You Save₹4.24 (14% on MRP)
ContainsChlordiazepoxide(5.0 Mg) + Amitriptyline(12.5 Mg)
UsesDepression along with anxiety
Side effectsNausea, Vomiting, Dizziness, Confusion, Gain in weight, Xerostomia (dryness in the mouth)
Check more medicines with composition as Chlordiazepoxide(5.0 Mg) + Amitriptyline(12.5 Mg)

Uses of Amitril Plus Tablets

  • Amitril Plus Tabl is used to manage the following conditions:
  • Treatment of depression
  • Treatment of anxiety (associated with depression where the person is unable to speak, express themselves, or feel comfortable while in situations of sudden urgency or, some cases, activities of everyd...
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Contraindications of Amitril Plus Tablets

  • Before starting treatment with an Amitril Plus Tab, inform your doctor if any of the following statements are true:
  • If you have been diagnosed with obesity (excessive weight because of high concentration of fat deposits)
  • If you have been diagnosed with Chronic Obstructive Pulmonary Disorder (COPD)
  • If you have liver disease
  • If you have been diagnosed with uncontrolled hypertension (high blood pressure)
  • If you have been diagnosed with diabetes (increased blood sugar levels)
  • If you have been diagnosed with arrhythmia (irregular heartbeat)
  • If you have any other uncontrolled heart disease
  • If you have been diagnosed with hyperthyroidism (increased thyroid levels)

Side effects of Amitril Plus Tablets

  • The common side effects of Amitril Plus Tab are as follows:
  • Nausea
  • Vomiting
  • Diarrhoea
  • Xerostomia (dryness in the mouth)
  • Weight gain
  • Sleepiness
  • Nervousness
  • Confusion

Precautions and Warnings of Amitril Plus Tablets



Can I take Amitril Plus Tab during pregnancy?
No. Studies have shown that Amitril Plus Tab is not safe to take during pregnancy. There is a potential risk to the life of the baby. Talk to your doctor if you wish to take this medicine while pregnant.

Breast Feeding

Can I take Amitril Plus Tab while breastfeeding?
It is not advised to take this medicine while breastfeeding. Some studies show that it is harmful to the baby. Always consult your doctor before taking this medicine.


Can I drive if I have taken Amitril Plus Tab?
It is not advisable to drive after taking an Amitril Plus Tab. Since it causes dizziness and confusion, it can be unsafe to drive after taking this medicine.


Can I consume alcohol with the Amitril Plus Tab?
No. Alcohol causes dizziness and confusion, and so does this medicine. Mixing the two can be harmful and may enhance the side effects of this medicine. It is not safe to consume alcohol after taking this medicine.

Other General Warnings

Talk to your doctor if
  • Your side effects persist for longer than usual.
  • You experience dizziness and nervousness.
  • You are trying to conceive.
  • You are lactating.
  • You are a chronic alcohol user.
  • You are taking other medicines.
  • You are taking alternative medicine like herbal medicines or homoeopathy.

Mode of Action of Amitril Plus Tablets

How Does It Work?

Amitril Plus tab has two main components called amitriptyline and chlordiazepoxide. These components come under the class of tricyclic antidepressants (TCA). While the specific action of amitriptyline...
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Directions for Use of Amitril Plus Tablets

  • Swallow the tablet as a whole with water; do not chew or crush it.
  • Do not take without consulting a doctor. Amitril Plus Tab is a prescription medicine.
  • Do not skip or stop this medicine suddenly, even if you start feeling better.
  • Take it at the same time every day.
  • Take it with or without food, depending upon your doctor's instructions.
  • Talk to your doctor if side effects persist, even though they usually go away after some time.

Interactions of Amitril Plus Tablets

Interactions with other medicines

  • To avoid adverse effects caused by medicine interaction, inform your doctor about all medicines and supplements (including herbal medicines and supplements, and multivitamins) you are currently taking...
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  • Antibiotics - linezolid - for bacterial infections efficiency can reduce the effectiveness of both the treatments.
  • Anticholinergic medicines (used in the treatment of breathing disorders) can cause difficulty in breathing or breathlessness.
  • Medicines that contain sympathomimetic agents like phenylephrine and isoproterenol (used in heart emergencies) can interact with the Amitril Plus Tab and cause an abrupt heart rate that can lead to re...
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  • Antifungal medicines like fluconazole with Amitril plus Tab can increase the side effects.
  • Anti-tubercular medicine like rifampicin interact with these medications and cause an elevation in depression and sedation.

Interactions with food items

  • As Amitril Plus Tab causes an increase in weight, it is advised to eat a healthy diet rich in vitamins and minerals, including green leafy vegetables and low sugar content diets.

Storage and disposal of Amitril Plus Tablets

Store the medicine in its original packing. Keep the tablets away from moisture and out of direct sunlight. Keep away from children and pets. Exchange facilities with local pharmacists can be used to ...
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Dosage of Amitril Plus Tablets


Symptoms of an Amitril Plus Tab overdose include nausea, vomiting, confusion, and in extreme cases, coma. If you suspect an overdose or experience these symptoms, contact your doctor or visit the near...
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Missed a Dose

In case of a missed dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not doubl...
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Content Details


Dr. Tanya Gupta

BDS (Bachelor’s in Dental Surgery), MPH (Masters in Public Health)


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Can I stop taking Amitril Plus Tab if I start feeling better?

A: No. Always consult your doctor before starting or stopping any medicine between its course.

Q: Is Amitril Plus Tab a habit-forming medicine?

A: Yes, Amitril Plus Tab is a habit-forming medicine. It is always advised to take it at the proper dosing schedule and not repeat doses.

Q: Can Amitril Plus Tab cause a change in my lifestyle?

A: Yes. This medicine can make you feel confused and nauseated. Amitril Plus Tab can also lower your sexual desires. These side effects usually go away after some time, but contact your doctor if they persist for long.
Last Updated on: 16 Mar 2022 | 11:42 AM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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