Adxate 10mg Tablets
Description
Adxate 10mg Tablets contains methotrexate, as an active ingredient. It belongs to a class of medicines called antimetabolites. It is used in the treatment of rheumatoid arthritis and psoriasis. It i
s a prescription medicine, so never suggest this medicine to anyone, even if their condition is similar to yours. The doctor decides the dosage and frequency of taking this medicine based on clinical condition and response to treatment. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting Adxate 10mg Tablets .
Product Summary
Offer Price | ₹38.84 |
You Save | ₹12.27 (24% on MRP) |
Contains | |
Uses | Psoriasis and rheumatoid arthritis |
Side effects | Stomach discomfort, mouth ulcers, nausea, loss of appetite |
Therapy | ANTI-NEOPLASTIC |
Uses of Adxate 10mg Tablets
Contraindications of Adxate 10mg Tablets
- If you are allergic to Adxate 10mg Tablets or any of the ingredients of this medicine.
- If you are pregnant or breastfeeding.
- If you have any underlying medical condition like severe liver and kidney disorders.
- If you have low levels of white blood cells and platelets.
- If you recently had an injection of live vaccines.
- If you have mouth ulcers, or have ulcers in stomach or intestine
- If you are a chronic alcoholic
Side effects of Adxate 10mg Tablets
- Stomach discomfort
- Mouth ulcers
- Nausea
- Loss of appetite
- Drowsiness
- Muscle pain
Precautions and Warnings of Adxate 10mg Tablets
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have any medical condition like blood disorder, kidney disorder, intestinal disorder, lung disease, a brain-related disorder etc.
- You have mouth ulcers.
- You have diabetes or are being treated with insulin.
- You should take proper contraceptive measures during the treatment and should avoid pregnancy at least for 6 months after the treatment stops.
- Do not start, alter or stop this medicine on your own.
- You are giving this medicine to children.
- Consult your doctor regularly when on the treatment. He/she may monitor your blood, kidney, liver tests
- You experience irregular menses or blood in urine or sputum
- You develop fever , chills or any infection
- You develop shortness of breath
- Do not recommend this medicine to others.
- The medicine is restricted to prescription use.
Mode of Action of Adxate 10mg Tablets
How Does It Work?
- Adxate 10mg Tablets acts by decreasing inflammation that leads to joint pain, destruction in rheumatoid arthritis. It prevents further joint damage.
- In psoriasis, it suppresses the overactive immune system which helps control skin lesions of psoriasis.
Directions for Use of Adxate 10mg Tablets
- Take the dosage of Adxate 10mg Tablets as per the doctor's prescription.
- This medication should be taken by mouth only.
- Do not take this medicine beyond the prescribed dose.
- Swallow this medicine whole with water.
- The medicine should not be chewed, crushed or broken.
Interactions of Adxate 10mg Tablets
Interactions with other medicines
- Some medicines can affect the way Adxate 10mg Tablets works, or sometimes Adxate 10mg Tablets itself can reduce the effectiveness of other medicines if taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking medicines to treat diabetes, painkillers, water pills, medicines to treat skin disorders, antibiotics, antiepileptic medicines, medicines used in chemotherapy, medicines to treat asthma, immunosuppressants etc....
- Also if you are taking medicines containing folic acid along with this medicine, caution is advised.
Storage and disposal of Adxate 10mg Tablets
- The medicine should be kept away from children.
- Do not use this medicine after the expiration date mentioned on it.
- Store this medicine in a closed container.
- Store this medicine at room temperatures not exceeding 25 degrees Celsius.
Dosage of Adxate 10mg Tablets
Overdose
Missed a Dose
Content Details

Dr. Arpit Verma
MBBS, MD CCEBDM Diabetology

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What should I let my healthcare provider know before using Adxate 10mg Tablets ?
Q: How long will it take to feel better with the intake of this medicine?
Q: Is this medicine available in any other form?
References
- Methotrexate [Internet]. Webmd.com. [cited 11 Mar 2025].
- Maxtrex 2.5 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. [cited 11 Mar 2025].
- Medex tablet [Internet]. medex.com.bd. [cited 11 Mar 2025].
- DrugBank. Methotrexate. [cited 11 Mar 2025].
- U.S. Food and Drug Administration. Methotrexate [package insert]. [cited 11 Mar 2025].
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 126941, Methotrexate. [cited 11 Mar 2025].
- ScienceDirect. Methotrexate.[cited 11 Mar 2025].
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