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Adpep N Tablets

10 Tablet(s) in Strip
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Adpep N Tablets Description

Adpep N Tablet is an analgesic medication. It contains a combination of nimesulide and serratiopeptidase as active substances. Adpep N Tablet is used in the treatment of sudden and sharp pain. It is

also used for the treatment of the symptoms of osteoarthritis and painful periods. This medicine can be used in adults and adolescents adults above 12 years of age. Adpep N Tablet works by preventing the action of inflammatory chemicals in the body. Take this medicine in the exact dose and duration as prescribed by your doctor. Before starting Adpep N Tablet, inform your doctor if you are pregnant/breastfeeding and about your complete medical history.


Product Summary

Offer Price₹55.77
You Save₹7.60 (12% on MRP)
ContainsNimesulide(100.0 Mg) + Serratiopeptidase(10.0 Mg)
UsesPain, painful periods, osteoarthritis
Side effectsNausea, vomiting, diarrhoea, abdominal pain
Check more medicines with composition as Nimesulide(100.0 Mg) + Serratiopeptidase(10.0 Mg)

Uses of Adpep N Tablets

  • Adpep N Tablet is used to treat sudden and sharp pain.
  • It is also used for the treatment of symptoms of osteoarthritis and painful periods (dysmenorrhoea).

Contraindications of Adpep N Tablets

  • If you are allergic to nimesulide, serratiopeptidase, or any ingredient of Adpep N Tablet.
  • If you have a history of allergic reactions (wheezing, coughing, sneezing, nose blockage, runny nose, itching, red/itchy rashes) to other non-steroidal anti-inflammatory medicines like aspirin.
  • If you have a history of liver damage caused by nimesulide.
  • If you are exposed to other potentially liver-damaging substances.
  • If you are an alcoholic or drug addict.
  • If you have or had a history of stomach bleeding, ulcer, and inflammation of the stomach lining prior to treatment with non-steroidal anti-inflammatory medicines.
  • If you have a recurrent active stomach/intestinal ulcer or have had it in the past (two or more distinct episodes of proven ulceration or bleeding).
  • If you have problems related to blood clotting and bleeding disorders.
  • If you have liver or kidney disorders.
  • If you have a serious heart failure problem.
  • If you are suffering from symptoms of flu-like fever, chills, and shivering.
  • If you are giving this medicine to children under 12 years of age.
  • If you are pregnant or breastfeeding.

Side effects of Adpep N Tablets

  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Flatulence (gas)

Precautions and Warnings of Adpep N Tablets



Can I take Adpep N Tablets during pregnancy?
Adpep N Tablet should not be used during pregnancy unless recommended by the doctor. This medicine is contraindicated for use in the last three months of pregnancy. Talk to your doctor if you are planning a pregnancy or think you may be pregnant.

Breast Feeding

Can I take Adpep N Tablets while breastfeeding?
No information is available if Adpep N Tablet passes into human breast milk. This medicine is contraindicated for use in breastfeeding women.


Can I drive if I have consumed Adpep N Tablets?
There is limited information on the effect of Adpep N Tablet on driving ability. However, if you experience any effects after taking this medicine that may affect your ability to drive safely, it is advised to avoid driving.


Can I consume alcohol with Adpep N Tablets?
You should avoid consuming alcohol during the treatment with Adpep N Tablet as it may worsen your liver problems.

Other General Warnings

Talk to your doctor if
  • You are taking medicines called non-steroidal anti-inflammatory medicines (NSAIDs), corticosteroids, blood thinners like warfarin, selective serotonin reuptake inhibitors (SSRIs) like fluvoxamine, or ...
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  • You experience symptoms like loss of appetite, nausea, vomiting, stomach pain, dark urine, and weakness. These could be signs of liver damage.
  • You develop black tarry stools or vomit blood.
  • You are elderly.
  • You have liver, kidney, or heart disease.
  • You have a history of stomach or intestine ulcers.
  • You have any upcoming surgery.
  • You experience severe skin reactions after using this medicine.
  • You are a woman trying to get pregnant.

Mode of Action of Adpep N Tablets

How Does It Work?

  • Adpep N Tablet contains a combination of nimesulide and serratiopeptidase as active substances.
  • Nimesulide is a non-steroidal anti-inflammatory medicine (NSAID) that blocks the action of a chemical called cyclooxygenase. Cyclooxygenase is responsible for the formation of certain substances in th...
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  • Serratiopeptidase is an enzyme that helps in breaking down or dissolving the abnormal proteins at the site of inflammation and promotes healing.

Directions for Use of Adpep N Tablets

  • Take Adpep N Tablet as a whole with sufficient water.
  • Always take this medicine exactly as prescribed by your doctor.
  • Do not cut, break, or chew the medicine.
  • Do not consume more than the prescribed dose.

Interactions of Adpep N Tablets

Interactions with other medicines

  • Some medicines can affect the way Adpep N Tablet works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Inform your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • The simultaneous use of Adpep N Tablet with other non-steroidal anti-inflammatory medicines like aspirin is not recommended.
  • You may experience stomach bleeding and ulcers if this medicine is used along with corticosteroids, platelet inhibitors (clopidogrel), and selective serotonin reuptake inhibitors (fluoxetine).
  • This medicine may interfere with the working of blood thinners like warfarin.
  • Adpep N Tablet can reduce the effect of medicines used to treat high blood pressure like hydrochlorothiazide, furosemide, and captopril.
  • Particular care should be taken if you are taking medicines used for treating mental disorders like lithium, asthma/COPD like theophylline, diabetes like glibenclamide, heart failure like digoxin and ...
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  • Caution is required when Adpep N Tablet is taken less than 24 hours before or after treatment with methotrexate - an anti-cancer medicine.

Storage and disposal of Adpep N Tablets

  • Store Adpep N Tablet in a cool and dry place away from direct sunlight.
  • Keep out of reach of children and pets.

Dosage of Adpep N Tablets


Symptoms of overdose of Adpep N Tablet include nausea, vomiting, drowsiness, sluggishness and stomach pain. If you think you have taken too much of this medicine, contact your doctor immediately or vi...
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Missed a Dose

If you missed any dose of Adpep N Tablet, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a doub...
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Content Details


Dr. Arpit Verma

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What is Adpep N Tablet used for?

  • Adpep N Tablet is used to treat sudden and sharp pain.
  • It is also used for the treatment of the symptoms of osteoarthritis and painful periods (dysmenorrhoea).

Q: Is Adpep N Tablet banned in India?

  • Yes, the Health Ministry has banned the fixed medicine combination (FDC) of nimesulide and serratiopeptidase, which includes Adpep N Tablet.
Product Details
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Last Updated on: 09 Jun 2022 | 04:34 PM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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