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Vildagliptin

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Molecule Summary

Uses
Type 2 Diabetes mellitus
Therapy
Anti-Diabetic
Side Effects
Nausea, tiredness, dizziness, headache, low blood sugar
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Molecule Description

Vildagliptin is an antidiabetic medicine. This medicine helps lower blood glucose by inhibiting specific enzymes that degrade substances known as Incretins. Incretins are hormones produced by the small intestine to control the level of blood glucose levels. They also stimulate the production of insulin after having food. Thus they help in lowering blood glucose. Take Vildagliptin as advised by your doctor. Do not miss or skip any meal of the day along with Vildagliptin. Before starting this medicine, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your complete medical history. Type 2 diabetes mellitus is a condition in which your pancreas does not make enough insulin to keep blood sugar levels under control, and your body is also unable to use its own insulin adequately. This causes high blood sugar levels in your body, which can cause medical problems like heart disease, kidney disease, blindness and poor blood flow in your hands and legs. Along with taking this medication, it is critical that you make certain lifestyle changes such as exercising regularly, avoiding smoking and drinking alcohol, and eating a balanced diet with plenty of fruits and vegetables to maintain proper blood sugar control.

Uses

For the management of type 2 diabetes mellitus.

Contraindications

When should one not use Vildagliptin

If you are allergic to vildagliptin or any of the other ingredients of this medicine.

Side effects

Common side effects of this drug are:

  • Nausea
  • Tiredness
  • Dizziness
  • Headache
  • Low blood sugar (you may experience symptoms of low blood sugar like trembling, sweating, anxiety, blurred vision, tingling lips, paleness, irritability or confusion)

Precautions and Warnings

Pregnancy

Pregnancy

You should not take Vildagliptin during pregnancy. Limited information is available about its safety in pregnancy. This medicine should not be taken if you are pregnant unless your doctor considers it essential.

Breast Feeding

Breast Feeding

It is advised not to breastfeed when you are taking this medicine as limited information is available on how Vildagliptin can affect your baby. Consult a doctor, your doctor will tell you about the use of this medicine after assessing the benefits over risks.

Driving

Driving

There is limited information related to its effect on driving ability. However, sometimes you may experience dizziness after taking this medicine. So it is advised to be careful while driving or operating machinery.

Alcohol

Alcohol

This medicine should not be consumed with alcohol as it affects blood glucose levels. It can decrease or increase the blood sugar level depending on the quantity and frequency of alcohol consumption. It also interferes with the liver's activity.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have liver and kidney function problems or if you are on dialysis.
  • You have heart problems like irregular heart rhythm and heart failure as it may increase the symptoms further.
  • You have a known history of pancreatitis or develop sudden pain in the stomach or back, immediately stop the medicine and report to the hospital.
  • You experience skin problems.
  • You may find increased liver enzymes in blood test reports.
  • It should not be used for patients having Type 1 Diabetes (your body does not produce insulin).
  • You are taking any other medicines for diabetes like Glibenclamide (sulphonylurea) along with this medicine, you may experience a sudden fall in blood glucose level. The doctor might need to reduce the dosage to reduce this risk.

Mode of Action

How Does It Work?

Vildagliptin works by inhibiting enzymes that degrade chemical substances known as "incretins". Incretins play an important role to control blood glucose levels. Thus the levels of incretin are maintained, thereby lowering the blood glucose.

Interactions

Interactions with other medicines

  • Concomitant use of Vildagliptin with medicines like water pills, corticosteroids, thyroxin and also medicines which affect the brain functions or central nervous system can reduce the effect of Vildagliptin.
  • There may be a risk of swelling on the face, lips, tongue on concomitant use of captopril, enalapril, fosinopril to treat high blood pressure.

Dosage

Overdose

Symptoms of overdose may include prickling sensation, fever, swelling etc. If you think you have taken too much of this medicine contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of this medicine, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

This disease cannot be cured completely. However, you can control it. Here are a few simple tips to control diabetes: Plan your diet, consume a balanced diet. Limit carbohydrate and sugar intake. Exercising regularly is necessary. Monitor your blood glucose regularly. Take your anti-diabetic medication on time.

A diet should be high in fibre, low in fat with adequate protein, carbohydrates, vitamins and minerals. Maintain the regular meal timings and try to have 2-3 healthy snacks between meals like soups and salads. Diet should include boiled, steamed or baked food. Ensure moderate use of edible oils (groundnut oil, olive oil), less use of ghee and butter. Drink at least 8-10 glass of water daily. Carry fruit or low-calorie high fibre biscuits while travelling.

No, you should never stop taking Vildagliptin without consulting the doctor. Abruptly stopping the medicine results in a sudden rise in blood glucose levels and cause further harm to the kidney and other organs.

Take Vildagliptin as prescribed by the doctor during day or night for the prescribed duration. Take with food, as a whole, with a glass of water. Avoid skipping meals as well as medicine.

Nausea, tiredness, dizziness, headache, low blood sugar level are a few common side effects of Vildagliptin. These symptoms are usually mild and resolve with time.

Yes. Vildagliptin and Galvus, both the medicines have the same active ingredient that is vildagliptin.

Vildagliptin is used for the management of type 2 diabetes mellitus.

No, Vildagliptin does not cause weight gain. However, if you experience any weight variation and it bothers you, consult a doctor.

Vildagliptin is an antidiabetic class of medicine that helps to lower blood glucose levels.

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