Varenicline
SHARE
Molecule Summary
| Uses | Smoking cessation |
| Therapy | Deaddiction |
| Side Effects | Nausea, headache, dizziness, sleep problems, unusual dreams |
Medicines
available
19k pincodes
Molecule Description
Varenicline is a prescription medicine used to help you stop smoking. It is suitable for adults who are motivated to quit and need medical support to manage nicotine cravings and withdrawal symptoms. When you stop smoking, your body may react with irritability, restlessness, low mood, sleep problems, or strong urges to smoke. Varenicline helps reduce these symptoms and also lowers the satisfaction you may feel if you smoke during treatment, making it easier for you to stay committed to quitting. It should be used along with medical guidance and regular follow-up from your doctor.
Varenicline works by acting on specific receptors in your brain that are involved in nicotine dependence. It partially stimulates these receptors to reduce cravings and withdrawal discomfort, while also blocking nicotine from cigarettes so that smoking feels less rewarding. This supports your effort to quit smoking and helps prevent relapse. Because quitting smoking itself can affect your mood and behaviour, it is important to monitor how you feel during treatment and inform your doctor about any concerning changes.
You should take Varenicline exactly as advised by your doctor. Treatment usually starts with a low dose that is gradually increased over the first week to allow your body to adjust and to reduce side effects like nausea. The medicine should be taken with water and can be taken with or without food. Try to take it at the same time each day. Your doctor will usually advise a treatment duration of about 12 weeks, which may be extended if needed to help you remain smoke-free.
Varenicline may cause side effects, although not everyone gets them. Commonly reported side effects include nausea, headache, dizziness, sleep problems, unusual dreams, constipation, diarrhoea, dry mouth, and tiredness. Some people may notice changes in mood, anxiety, or low mood while quitting smoking. If you experience severe side effects or any changes in mood or behaviour that worry you, contact your doctor immediately.
Uses
- Management of nicotine addiction/smoking cessation in adults
- Reduces craving for cigarettes
- Eases withdrawal symptoms after stopping smoking
- Lowers the enjoyment of smoking if you relapse during treatment
Contraindications
When should one not use Varenicline
- If you are allergic to varenicline or any of the other ingredients of this medicine
- If you have had a serious allergic reaction, such as swelling of the face, lips, tongue, or throat, after taking varenicline earlier
- If you have experienced severe skin reactions like blistering, peeling, or painful rashes after using varenicline
Side effects
Common side effects of this drug are:
- Feeling nauseous or sick
- Headache or dizziness
- Trouble sleeping or unusual dreams
- Constipation, diarrhoea, or stomach discomfort
- Dry mouth and feeling tired
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have kidney disease, have had a kidney transplant, or have liver disease
- You have a history of depression, anxiety, or any other mental health condition
- You notice changes in mood, behaviour, or thoughts of self-harm while taking Varenicline
- You have heart disease or have had a heart attack or stroke earlier
- You have a history of seizures or epilepsy
- You experience chest pain, shortness of breath, or sudden weakness on one side of the body
- You develop a skin rash, blistering, peeling of skin, or sores in the mouth or eyes
- You have swelling of the face, lips, tongue, or throat, or difficulty breathing
- You feel unusually dizzy, very sleepy, or have a brief loss of consciousness
- You consume alcohol regularly or notice increased effects of alcohol while on Varenicline
- You are pregnant, planning to become pregnant, or breastfeeding
- You are taking other medicines and are unsure if they are safe to use with Varenicline
Mode of Action
How Does It Work?
Varenicline works on specific receptors in your brain that are involved in nicotine addiction. It reduces the rewarding effect of nicotine from cigarettes and helps control cravings and withdrawal symptoms, making quitting smoking more manageable.
Interactions
Interactions with food items
Varenicline can be taken with or without food.
Dosage
Overdose
If you take more Varenicline than prescribed, seek medical help immediately or visit the nearest hospital. Carry the medicine pack with you.
Missed a Dose
If you forget a dose, take it as soon as you remember. If it is close to your next dose, skip the missed one. Do not take a double dose to make up for a missed one.
Frequently Asked Questions (FAQs)
Articles
View AllDid you find this helpful?
References:
Explore More at Pharmeasy
Why trust PharmEasy?
# ONE OF INDIA'S MOST TRUSTED HEALTHCARE PLATFORM
CODAvailable
100%Genuine Medicine
30 DAYReturn Policy









