Ulipristal Acetate
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Molecule Summary
| Uses | Uterine fibroids |
| Therapy | Drugs Acting On Uterus |
| Side Effects | Absence of menstrual periods, Headache, Endometrial hyperplasia |
Medicines
available
19k pincodes
Molecule Description
Ulipristal Acetate is used in the treatment of uterine fibroids (a non-cancerous growth in the uterus). It is also used as a pre-operative treatment in women of reproductive age.
Uses
- Treatment of uterine fibroids
Contraindications
When should one not use Ulipristal Acetate
- If you are allergic to the active or inactive components of Ulipristal Acetate.
- If you have cancer, whether it is suspected or confirmed (ovarian, cervical, breast, or uterine). Your doctor will closely monitor your clinical status if you have a family history of cancer.
Side effects
Common side effects of this drug are:
- Absence of menstrual periods
- Headache
- Endometrial hyperplasia
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have STIs. Ulipristal Acetate is ineffective in the treatment or prevention of sexually transmitted illnesses.
- You experience symptoms of an allergic reaction to Ulipristal Acetate, such as a skin rash, itching/swelling anywhere on your body, dizziness, difficulty breathing, etc.
- Due to a lack of safety and efficacy data, Ulipristal Acetate should not be given to children under the age of 18.
- You have asthma and are using steroid medicines. Talk to your doctor before using this medicine.
Mode of Action
How Does It Work?
Ulipristal Acetate is a selective progesterone receptor modulator. It operates by altering progesterone's activity (natural female hormone). It is used in the treatment of fibroids either before surgery or on an intermittent basis (at regular intervals). It helps reduce the size of fibroids, the cessation or management of bleeding, and the rise of red blood cell count.
Interactions
Interactions with other medicines
- To avoid side effects associated with medicine interaction, it is important to inform the doctor about all medicines and health supplements you are currently taking.
- Ulipristal Acetate is known to interact with the following medicines:
- By competing for the progesterone receptor, hormonal contraceptives and progestogens are expected to reduce the efficacy of ulipristal acetate. As a result, using progestogen-containing medicines at the same time is not suggested.
- Long-term use of ritonavir, rifampicin, rifabutin, carbamazepine, oxcarbazepine, phenytoin, fosphenytoin, phenobarbital, primidone, efavirenz, nevirapine, markedly reduced Cmax and AUC of ulipristal acetate and its active metabolite by 90% or more and decreased ulipristal acetate half-life by 2.2-fold corresponding to an approximately 10-fold decrease of ulipristal acetate exposure.
Interactions with food items
- No information is available on the interaction of Ulipristal Acetate with food. Please seek medical advice.
Dosage
Overdose
Ulipristal Acetate should never be taken in excess of the recommended dose. If you have taken an overdose of this substance, seek medical help right away.
Missed a Dose
If you have missed a dose of Ulipristal Acetate, take it as soon as you can. However, if the gap is too long or the next dose is approaching, skip the missing dose and return to your regular schedule. Do not take two doses.
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