Triptorelin

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NPPA
Regulated

Molecule Description

Triptorelin is a hormone similar to Gonadotropin-Releasing Hormone (GnRH), which is naturally present in our body.

Uses

Prostate cancer
Endometriosis
Uterus fibroids
Infertility in women
Early puberty in children

Contraindications

When should one not use Triptorelin

Do not take this medicine if you are allergic to it or any of the other ingredients of this medicine
Do not take this medicine during pregnancy

Side effects

Common side effects of this drug are:

Hot flushes
Weakness
Excessive sweating, back pain
Pins and needles sensation in the legs
Reduced libido and impotence
Bone pain
Diarrhea
Hot flushes, allergic reactions
Swelling and pain at the injection site
Nausea
Stomach discomfort
The rise in blood cholesterol level and high blood pressure

Precautions and Warnings

Pregnancy

Triptorelin is not recommended in pregnancy because it is proven to harm the developing baby. Inform your doctor immediately if you are pregnant during treatment.

Breast Feeding

Do not take this medicine while breastfeeding.

Driving

If you experience any eye problems, sleepiness or if you feel tired after taking this medicine, you should not drive.

Alcohol

No known interaction is reported yet; you should discuss this with the doctor.

Other General Warnings

Talk to your doctor if

You are taking any medicines for blood clotting
You have diabetes or heart disease
You experience some vaginal bleeding in the first month of treatment
You suffer or have suffered from depression or anxiety
You notice any behaviour or mood changes after taking this medicine
You have diabetes and or have any heart condition
You are planning a pregnancy

Mode of Action

How Does It Work?

Triptorelin works by decreasing the production of sex hormones in the body. It acts on the pituitary gland and reduces stimulation of the production of sex hormones (testosterone and estradiol) from it.

Interactions

Interactions with other medicines

Promethazine
Medicines that increase prolactin level in the blood
Antiarrhythmic medicines (used to treat abnormal heartbeats)
Moxifloxacin
Some antipsychotic medicines
Any over the counter medicines, vitamins or herbal products that may interact with Triptorelin

Interactions with food items

No information is available on interactions of Triptorelin when taken with food, consult your doctor or pharmacist for further details.

Dietary Restrictions

No information is available on dietary restrictions while you are taking Triptorelin, consult your doctor or pharmacist for further details.

Dosage

Overdose

If you happen to take more than the prescribed dose of Triptorelin, seek emergency medical care.

Missed a Dose

If you have missed scheduling an appointment for taking your dose, immediately contact your doctor for an injection.

Frequently Asked Questions (FAQs)

Use this medicine with extreme caution in children because they are more sensitive to its side effectsPatients with the following conditions should be extra careful –Pituitary adenoma tumourWeight-related absence of periodsPolycystic Ovarian Disease (PCOD)Endometrial cysts in womenA metabolic bone disorder like Paget’s disease

Triptorelin is given as an injection in the muscle or under the skin and injected at the hospital by a trained person as prescribed by the doctor.