Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate
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Molecule Summary
| Uses | Male Hormonal Therapy |
| Therapy | Drugs For Male Hypogonadism |
| Side Effects | Acne, weight gain, breast enlargement, changes in voice |
Medicines
available
19k pincodes
Molecule Description
Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate is a testosterone replacement medicine used when the body is unable to produce enough of the natural male hormone testosterone. Testosterone is important for the development of male reproductive organs and features such as facial and body hair, a deeper voice, muscle growth, and sexual drive. When levels are very low, men may experience delayed puberty, decreased energy, infertility, weak bones, mood changes, and difficulty getting an erection. This medicine helps restore hormone levels, allowing these functions to improve.
Your doctor or nurse will give this medicine in a hospital or clinic. It is not meant for self-use at home. The dose and frequency depend on your condition and hormone levels. Regular follow-up is important because the doctor may adjust your dose based on your response and any side effects. Monitoring may include blood tests for haemoglobin, calcium, electrolytes, and prostate health.
This medicine is not suitable for everyone. It should not be used by individuals allergic to testosterone, those with prostate tumours or breast cancers, or anyone pregnant or planning pregnancy. It should also be avoided in people with peanut or soybean allergy. Before starting treatment, inform your doctor if you have heart, liver, kidney, or lung disease, sleep apnoea, diabetes, a history of blood clots, or high calcium levels. Your doctor will decide if this medicine is safe for you.
Some people may experience side effects such as acne, hair thinning, weight gain, pain at the injection site, breast enlargement in men, changes in mood or sleep, or an increase in red blood cells. Women receiving supportive therapy may notice a deeper voice or increased body hair. These effects vary from person to person, and your doctor will guide you on how to manage them if they occur. Avoid taking this medicine with certain other medications, such as warfarin, corticosteroids, or diabetes medicines, without consulting your doctor, as interactions may occur.
Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate does not generally affect your ability to drive, and there is no strong evidence of harmful interaction with alcohol, although it is still better to avoid drinking during treatment. If you experience anything unusual after the medicine or have any concerns, report them to your doctor promptly. Proper use under medical supervision helps ensure the treatment is effective and safe.
Uses
- To treat the deficiency of the male sex hormone 'Testosterone' in males (Hypogonadism) and provide relief from the symptoms of hormonal deficiency like delay in the development of sexual characteristics (delayed puberty), inability to achieve an erection, infertility, low sex drive, tiredness, weakened bones, and mood swings.
- As supportive therapy for females who want to get their gender changed (female to male transsexuals).
Contraindications
When should one not use Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate
- If you are allergic to testosterone or any active ingredients in Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate.
- If you have an allergy to peanuts or soybeans (as some inactive ingredients in this medicine may worsen your allergy).
- If you have, or suspect you have, a tumour of the prostate gland or breast cancer.
- If you are pregnant or are planning a pregnancy.
Side effects
Common side effects of this drug are:
- Acne
- Weight gain
- Enlargement of the breast in males
- Increase in the size of the prostate gland
- Hair loss
- Disturbed sleep
- Decreased sperm production in males
- Increase in red blood cells and haemoglobin
- Pain at the site of injection
- Repression of periods/menstrual cycle in women
- Development of masculine characteristics, such as a deep voice and an increase in body and facial hair
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have or have ever experienced an allergy to testosterone medication.
- You are suffering from health conditions like breast cancer, endometrial cancer, kidney and/or lung cancer, kidney disease, liver disease, diabetes, fits, migraine, and an enlarged prostate with difficulty in passing urine.
- You have a blood-related disorder, such as a condition in which blood clots more easily than normal, which increases the risk of blood clots (thrombophilia).
- You are prone to blood clots in veins or are suffering from blood-clotting disorders.
- You have high levels of calcium in your blood (hypercalcemia) and overproduction of parathyroid hormone (hyperparathyroidism).
- You have ever experienced a heart attack or stroke.
- You are suffering from a condition in which water builds up in your body (oedema).
- You are suffering from a serious breathing disorder wherein the breathing repeatedly stops and starts during sleep (sleep apnoea), as your condition may get worse if you are using testosterone.
- It is recommended that electrolyte, haemoglobin, and calcium levels, along with prostate levels, be regularly monitored in those receiving this treatment.
Mode of Action
How Does It Work?
Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate contains testosterone, which works as a hormone replacement therapy in those who have little or no of the natural male sex hormone testosterone. This medicine helps in the development of male secondary sexual characteristics, such as body and facial hair, and a deep voice in men with a deficiency of testosterone.
Interactions
Interactions with other medicines
- Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate improves glucose utilization; thus, the dose of insulin or other antidiabetic medications should be adjusted when used together. Hence, inform your doctor if you are taking any antidiabetic medicines.
- This medicine enhances the action of blood-thinning medicines like warfarin, hence concomitant use should be done with caution.
- Concomitant use of Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate along with medicines used for inflammatory conditions (corticosteroids) may increase the risk of fluid being built up in the body, which is fatal if you are suffering from heart or kidney diseases.
Dosage
Overdose
Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate will be given by a doctor or nurse, thus the chances of an overdose are unlikely. However, if you experience any discomfort or specific symptoms, inform your doctor immediately.
Missed a Dose
It is unlikely that the dose of this medicine will be missed if you are monitored in a healthcare setup. However, if you have missed taking any dose of this medicine, inform your doctor or nurse immediately.
Frequently Asked Questions (FAQs)
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References:
- Testosterone [Internet]. Ncbi.nlm.nih.gov. 2021 [cited 6 Jun 2026]
- Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate, 250mg/ml solution for injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 6 Jun 2026]
- Testosterone Propionate+Testosterone Phenyl Propionate+Testosterone Isocaproate, 250mg/ml solution for injection - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 6 Jun 2026]
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