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Terlipressin

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Molecule Summary

Uses
Bleeding oesophageal varices
Therapy
Haemostatics
Side Effects
Headache, hypertension, hypotension, paleness, transient abdominal cramps, diarrhoea
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Molecule Description

Terlipressin is used for the treatment of bleeding oesophageal varices (bleeding from dilated veins in the food pipe leading to your stomach). Terlipressin will be given to you by a doctor or nurse at the hospital setting or a clinic. Inform your doctor about all the known medical conditions, medical and medication history as well as all the medicines you are taking, including herbal supplements.

Uses

  • Terlipressin is used for the treatment of bleeding oesophageal varices (bleeding from dilated veins in the food pipe leading to your stomach).

Contraindications

When should one not use Terlipressin

If you are allergic to terlipressin or any other ingredient of this medicine.

Side effects

Common side effects of this drug are:

  • Headache
  • Hypertension
  • Hypotension
  • Paleness
  • Transient abdominal cramps
  • Diarrhoea

Precautions and Warnings

Pregnancy

Pregnancy

The use of Terlipressin is not recommended during pregnancy.

Breast Feeding

Breast Feeding

Limited information is available on the use of Terlipressin while breastfeeding.

Driving

Driving

No information is available on driving after taking Terlipressin.

Alcohol

Alcohol

No known interactions with alcohol.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have severe bleeding in your food pipe (oesophagus).
  • You are suffering from a severe infection known as septic shock
  • You suffer from bronchial asthma or other conditions that affect your breathing
  • You suffer from uncontrolled high blood pressure, insufficient blood circulation in the heart vessels (e.g. angina), have previously had a heart attack (myocardial infarction), or you have hardening of the arteries (arteriosclerosis)
  • You suffer from irregular heartbeats (cardiac arrhythmias)
  • You have poor blood circulation to your brain (e.g. you have had a stroke) or to your limbs (peripheral vascular disease)
  • You suffer from impaired kidney function (renal insufficiency)
  • You suffer from disturbances in the level of salt (electrolytes) in your blood
  • You are suffering from the reduced amount of fluid in your circulation or have already lost a large amount of blood
  • You are pregnant
  • You are over the age of 70 years

Mode of Action

How Does It Work?

Terlipressin works on the walls of blood vessels which causes narrowing and decreases the blood flow into the affected veins. This helps to stop or slow the bleeding.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Terlipressin works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.

Dosage

Overdose

  • Your doctor or nurse will give Terlipressin. Therefore, it is less likely that you shall receive more of this medicine. If you experience any unusual symptoms right after receiving the medicine, seek medical help.

Missed a Dose

You will be monitored by your doctor or nurse on when the medicine should be given to you. It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed a dose, inform them.

Frequently Asked Questions (FAQs)

Terlipressin is used for the treatment of bleeding oesophageal varices (bleeding from dilated veins in the food pipe leading to your stomach).

Side effects associated with Terlipressin are headache, hypertension, hypotension, paleness and transient abdominal cramps, diarrhoea etc. If side effects persist, then inform your doctor.

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