Telmisartan+Hydrochlorothiazide
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Molecule Summary
| Uses | High blood pressure |
| Therapy | Anti-Hypertensive |
| Side Effects | Dizziness, loose stools, gas, dry mouth, cough |
Medicines
available
19k pincodes
Molecule Description
Telmisartan+Hydrochlorothiazide is a blood pressure-lowering medicine. It is used for the treatment of high blood pressure. This medicine contains a combination of telmisartan and hydrochlorothiazide as its active ingredients. Telmisartan+Hydrochlorothiazide should be taken as directed by the doctor and in doses and duration as prescribed. You can take it with or without food.
Do not stop taking this medicine without informing your doctor. While taking Telmisartan+Hydrochlorothiazide, try to incorporate a healthy diet and certain lifestyle modifications for better management of your blood pressure. Do not miss or skip the dose of the medicine. Sudden stopping of this medicine may result in worsening of the health condition.
Before beginning to take Telmisartan+Hydrochlorothiazide, it is important to inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding. Additionally, make sure to disclose all medications and supplements you are taking, as well as any conditions or diseases you are experiencing. This information will allow your doctor to ensure your safety while taking the medication.
Uses
Telmisartan+Hydrochlorothiazide is used in the treatment of high blood pressure.
Contraindications
When should one not use Telmisartan+Hydrochlorothiazide
- If you are allergic to telmisartan, hydrochlorothiazide or any of the ingredients of Telmisartan+Hydrochlorothiazide.
- If you are allergic to sulfonamide (sulfa) medicines.
- If you have serious liver disorders and problems related to the bile duct (a canal connecting the liver to the intestine), like cholestasis.
- If you have serious kidney problems.
- If your blood test shows a significant increase in calcium and a decrease in potassium levels.
- If you have diabetes or kidney problems and you are taking medicine for lowering blood pressure like Aliskiren.
Side effects
Common side effects of this drug are:
- Dizziness
- Loose stools
- Dry mouth
- Cough
- Muscle and back pain
- Fainting
- Tingling sensation
- Muscle ache
- Gas
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You feel giddy, especially after the first dose or during the initial days of the treatment.
- You have serious heart and heart valve-related problems like heart failure, etc.
- You develop eye problems like eye pain and a decrease in vision.
- You have been experiencing fluid loss within your body due to diarrhoea, vomiting, etc.
- You are facing problems with liver function and related organs-like cholestasis and biliary obstruction.
- Your kidneys are not functioning properly, or you have underlying kidney disease like renal artery stenosis (narrow kidney blood vessels).
- You are suffering from primary aldosteronism (a condition of excess production of the hormone aldosterone from the adrenal glands).
- If you have diabetes, as Telmisartan+Hydrochlorothiazide may affect your blood glucose levels, glucose monitoring is needed.
- You have an electrolyte imbalance of sodium, magnesium, and potassium and experience symptoms such as dry mouth, thirst, drowsiness, muscle pain, nausea, vomiting, etc.
Mode of Action
How Does It Work?
Telmisartan and hydrochlorothiazide in Telmisartan+Hydrochlorothiazide work together to lower blood pressure. Telmisartan blocks the angiotensin hormone, which causes blood vessels to narrow and blood pressure to rise. Hydrochlorothiazide increases urine production and loss of water/salt from the body, further lowering blood pressure.
Interactions
Interactions with other medicines
- Certain medicines can affect the way Telmisartan+Hydrochlorothiazide works, or this medicine itself can alter the action of other medicines taken along. Inform your doctor about your complete medication history including medicines that you are currently taking or might take.
- Especially if you are taking other blood pressure-lowering medicines, steroids, anti-infective medicines, medicines for brain-related disorders, muscle relaxants, anti-diabetic medicine, painkillers and medicines for a heart problem.
Interactions with food items
Telmisartan+Hydrochlorothiazide can be taken with or without food. It is important to avoid foods high in potassium, such as bananas, oranges, nuts, and sweet potatoes.
Dosage
Overdose
Symptoms of overdose may include low blood pressure, irregular heart rhythms, dizziness, excessive urination, nausea and vomiting. Seek urgent medical help if you think you have taken too many Telmisartan+Hydrochlorothiazide.
Missed a Dose
- It would be best if you never miss a dose of your blood pressure medicine as it may lead to serious high blood pressure-related problems.
- If you have missed any dose of Telmisartan+Hydrochlorothiazide, take it as soon as you remember, however, if it is time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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References:
- Telmisartan/Hydrochlorothiazide 40 mg/12.5 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 7 June 2026]
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 65999, Telmisartan. Retrieved January 6, 2025.
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 3639, Hydrochlorothiazide. Retrieved January 6, 2025.
- Messerli FH, Makani H, Benjo A, Romero J, Alviar C, Bangalore S. Antihypertensive efficacy of hydrochlorothiazide as evaluated by ambulatory blood pressure monitoring: A meta-analysis of randomized trials. Am Heart J. 2010 Sep;160(3):504-510. [cited 2026 Jun 7].
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