Tadalafil+Ambrisentan

When should one not use Tadalafil+Ambrisentan

• If you are allergic to ambrisentan, tadalafil, or any other ingredient in this medicine.
• If you are pregnant or a woman of childbearing age and not using any contraceptive measures.
• If you are a breastfeeding mother.
• If you have severe liver disease.
• If you are taking medicine known to cause vasodilator effects, such as amyl nitrate or nitrates.
• If you are taking riociguat medicine, used to treat arterial blood pressure.

Common side effects of this drug are:

• Headache
• Dizziness
• Irregular heartbeat
• Nausea
• Nasal congestion
• Tiredness
• Indigestion
• Back pain
• Peripheral oedema
• Sinusitis
• Flushing

Other General Warnings

• You have kidney or liver problems.
• You have anaemia or a reduced number of blood cells.
• You have swelling in your hands and feet due to fluid retention.
• You observe symptoms such as nausea, vomiting, fever, dark-coloured urine, stomach ache, etc. This could be a sign of the liver not working properly.
• You experience sudden vision loss or hearing loss.
• Tadalafil+Ambrisentan is not recommended for children below 18 years of age.
• You have any lung problems other than PAH.
• You have a history of heart problems such as heart failure, low blood pressure, stroke or heart blockage.
• You have a history of eye problems like retinitis pigmentosa (a genetic disorder that may cause loss of vision).

How Does It Work?

Interactions with other medicines

• To avoid any possible interaction, tell your doctor about all the medicines, supplements, or herbal supplements you are currently taking or might take.
• Especially if you are taking any other medicine to treat PAH.
• Other medicines that should be used with caution are immunosuppressants like ciclosporin and anti-tuberculosis medicines like rifampicin.
• Concomitant administration of Tadalafil+Ambrisentan along with medicines containing nitrates leads to severe hypotensive effects (low blood pressure).

Overdose

Missed a Dose