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Sevelamer Carbonate

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Molecule Summary

Uses
High blood phosphate levels
Therapy
Drug For Chronic Kidney Disease
Side Effects
Nausea, vomiting, diarrhoea
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Molecule Description

Sevelamer Carbonate is used to regulate the increased levels of phosphates in blood in individuals with severe kidney disease. It is also used in patients who undergo dialysis. It contains sevelamer, which belongs to a class of medicines known as phosphate binders. It works by binding to the phosphates and reduces the levels of phosphate in the blood. Sevelamer Carbonate should be taken as directed by the doctor and in doses and duration as prescribed.

Uses

Sevelamer Carbonate is used for the treatment of high blood phosphate levels in patients with severe kidney diseases and is also used in patients who undergo dialysis.

Contraindications

When should one not use Sevelamer Carbonate

  • If you are allergic to sevelamer or any other ingredients of Sevelamer Carbonate
  • If you have difficulty in passing stools
  • If you have low levels of phosphorous

Side effects

Common side effects of this drug are:

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Constipation

Precautions and Warnings

Pregnancy

Pregnancy

You should consult your doctor before using Sevelamer Carbonate as there is limited information about its safety during pregnancy. Your doctor will only prescribe you this medicine if considered essential after assessing the benefits over risks.

Breast Feeding

Breast Feeding

Consult your doctor before taking Sevelamer Carbonate while breastfeeding as it is unknown if sevelamer passes into breast milk.

Driving

Driving

It is unlikely that Sevelamer Carbonate will influence on your driving ability.

Alcohol

Alcohol

Although there is no known interaction with alcohol and Sevelamer Carbonate, it is essential to consult your physician if you have a habit of consuming alcohol regularly.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have undergone a major stomach or bowel surgery
  • You have problems with the bowel movement (digestion problem)
  • You have difficulty in swallowing foods or liquids
  • You have severe stomach pain or intestine disorders
  • You notice blood in your stools (gastrointestinal bleeding)
  • You are suffering from a condition when the parathyroid gland becomes overactive and leads to a raise in calcium level (hyperparathyroidism) and when thyroid gland doesn't produce enough thyroid hormone (hypothyroidism)
  • During the treatment you may develop low levels of vitamins A, D, E, K and folic acid in your blood and therefore your doctor may monitor these levels.

Mode of Action

How Does It Work?

Sevelamer works by binding with phosphates in the intestine and inhibits its absorption thus decreasing blood phosphorus levels. This in turn helps in preventing low calcium levels.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Sevelamer Carbonate works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • Sevelamer Carbonate can reduce the effect of the antibiotic ciprofloxacin when used together.
  • Medicines used for heart rhythm problems or for epilepsy like amiodarone, quinidine, phenytoin should be taken at least 1 hour before or 3 hours after Sevelamer Carbonate
  • Medicine used to treat acidity like omeprazole, pantoprazole or lansoprazole may interfere with the efficacy of this medicine on concomitant use
  • This medicine can reduce the effect of medicines acting on immune system like ciclosporin, mycophenolate mofetil and tacrolimus when used simultaneously.
  • Close monitoring of the hormone levels is recommended if this medicine is taken along with levothyroxine to treat low thyroid hormone levels.

Interactions with food items

Take Sevelamer Carbonate with meals, as directed by your doctor.

Dosage

Overdose

Symptoms of overdose may include nausea, vomiting, indigestion, diarrhoea, constipation, stomach pain.

Missed a Dose

In case you've missed any dose of Sevelamer Carbonate, take it as soon as you remember it. If it is almost time for the next dose, then skip the missed dose. Do not take a double dose to compensate for the missed dose.

Frequently Asked Questions (FAQs)

The dose and duration of Sevelamer Carbonate will depend on the response to treatment. Follow your doctor's instructions and do not stop taking this medicine on your own.

No, Sevelamer Carbonate does not contain a steroid. It contains sevelamer, which belongs to a class of medicines known as phosphate binders.

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