Rituximab

Uses	blood cancers and autoimmune disorders
Therapy	Anti-Neoplastic
Side Effects	Nausea, rash, pruritus, headache, fever, bacterial and viral infections, neutropenia

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Molecule Description

Rituximab is a targeted anticancer medicine used by cancer specialists in the treatment of different cancers including blood cancers. Rituximab is a monoclonal antibody that targets the unwanted activity of blood cells. This helps in managing cancer and various other non-cancerous conditions like certain autoimmune disorders. Routine blood tests are essential for checking your blood cell counts and monitoring hepatitis B. Before starting this medication, consult your healthcare provider if you have any heart conditions, or liver issues, plan to undergo surgery or vaccinations, or are currently taking any antibiotics. It's important to inform your doctor about all your medications. Rituximab is not recommended during pregnancy or while breastfeeding. Women who could become pregnant should use effective birth control during treatment and for at least 12 months afterwards. Talk to your doctor about contraception advice for men. The most common side effects of Rituximab include headaches, weakness, swelling, infections, and hair loss. This medication may lower the levels of red and white blood cells in your bloodstream, which can increase your risk of infections.

Uses

Rituximab is used by cancer specialists in the treatment of blood cancers and certain autoimmune disorders.

Contraindications

When should one not use Rituximab

You are allergic to rituximab or any of the other ingredients of this medicine.
You have an active, severe infection.
Your immune system is severely weakened.
You have severe heart failure or severe uncontrolled heart disease.

Side effects

Common side effects of this drug are:

Nausea
Rash
Pruritus
Headache
Fever
Bacterial and viral infections
Neutropenia

Precautions and Warnings

Pregnancy

Rituximab should be avoided in pregnancy. Women who could become pregnant should use effective birth control during treatment and for at least 12 months afterwards. Talk to your doctor about contraception advice for men.

Breast Feeding

Rituximab should not be used while breastfeeding.

Driving

Rituximab is unlikely to affect your ability to drive or use machines.

Alcohol

No known interactions with alcohol.

Other General Warnings

Talk to your doctor if

You have heart problems (such as angina, palpitations or heart failure) or breathing problems.
You have any vaccines scheduled.
You have a history of infections or you notice signs of infection during or after treatment.
You have neurological symptoms.
You have hepatitis B.
You develop severe skin reactions.
You are planning vaccinations.
You have low blood cell counts.
You experience infusion-related reactions.
You are pregnant, breastfeeding, or planning to become pregnant.

Mode of Action

How Does It Work?

Rituximab is a monoclonal antibody that targets the unwanted activity of blood cells. This helps in managing some cancers and autoimmune disorders.

Dosage

Overdose

Your doctor or nurse will give Rituximab. Therefore, the chances of overdose are very rare. If you experience the symptoms right after taking the medicine, seek medical help.

Missed a Dose

You will be monitored by your doctor or nurse on when the medicine should be given to you. It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed a dose, inform them.