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Quinine

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Molecule Summary

Uses
Malaria
Therapy
Anti-Malarial
Side Effects
Diarrhoea, nausea, vomiting, dizziness, stomach pain, headache
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Molecule Description

Quinine is an antimalarial medicine used to treat malaria. It may also be used to treat and prevent nighttime leg cramps. This medicine works by acting directly on malaria-causing organisms and thus inhibiting their growth. It should be taken as directed by the doctor and in the exact dose and duration as prescribed. Do not stop taking this medicine, even if you start feeling better after taking this medicine. Stopping this medicine suddenly may result in treatment failure and incomplete eradication of malaria-causing organisms from the body. Thereby, increasing the risk of re-infection. Before taking Quinine, inform the doctor if you are pregnant, planning a pregnancy or are breastfeeding and about your detailed medical history.

Uses

  • Quinine is used for the treatment of malaria.
  • It may also be used to treat and prevent nighttime leg cramps.

Contraindications

When should one not use Quinine

  • If you are allergic to quinine or any of the ingredients of this medicine.
  • If you have any kind of eye problem such as swelling in the eye or difficulty in vision.
  • If you have a condition of muscle weakness.
  • If you are suffering from ringing in the ears.
  • If you have any kind of blood-related disorder.

Side effects

Common side effects of this drug are:

  • Nausea
  • Vomiting
  • Stomach pain
  • Headache
  • Cough
  • Dizziness
  • Fatigue
  • Muscle or joint pain

Precautions and Warnings

Pregnancy

Pregnancy

Quinine can be recommended during pregnancy only if your doctor strictly considers it essential. If you are pregnant or think you may be or are planning for a baby, you should consult your doctor before taking this medicine.

Breast Feeding

Breast Feeding

A breastfeeding mother should take Quinine only under the doctor's recommendation. Refrain from self-medication.

Driving

Driving

Quinine makes you feel sleepy and dizzy and may affect your vision. Thus it is advised not to drive when you are taking this medicine.

Alcohol

Alcohol

Although there is no known interaction with alcohol along with this medicine, it is important to consult your physician if you drink too often.

Alcohol

Alcohol

However, consuming alcohol may aggravate some of the side effects. So it may be best to hold off on drinking alcohol until you finish the treatment.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have heart disorders like irregular heartbeat, slow heart rate, etc.
  • You have a history of malaria for a long time.
  • You were born or have any other medical condition that affects heart rhythm.
  • You have an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency.

Mode of Action

How Does It Work?

Quinine works by increasing the levels of heme (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

Interactions

Interactions with other medicines

  • Quinine may interact with other medications and provide an altered response to the treatment. Please notify your doctor if you are undergoing any other treatments, over-the-counter medications and herbal preparations.
  • Especially, if you are taking any other anti-malarial medicines like artemether with lumefantrine, chloroquine, etc., anti-coagulants, heart-related medicines, anti-epileptic medicines, medicines for brain-related disorders, antiparkinson medicine, etc.
  • Other medicines that should be used with caution are immunosuppressants like ciclosporin, antibiotics like moxifloxacin, anti-fungal medicines, muscle relaxants, anti-HIV medicines, anti-reflux medicines, painkillers, etc.

Dosage

Overdose

Symptoms of overdose may include headache, nausea, blurred vision, ringing in the ears, muscle twitching, etc. In case of an overdose, contact your doctor or reach out to your nearest hospital as soon as possible. Try to carry the pack of the medicine to make overdose assessment easier for doctor/hospital staff.

Missed a Dose

  • It would be best if you don't miss a dose of anti-malarial medicine as it may lead to treatment failure.
  • If you have missed taking any dose of Quinine, take it as soon as you remember.
  • If it's already the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
  • Never take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

No, it is important to complete the course of Quinine as prescribed by your doctor. You may feel better after the first dose, but to kill the malarial parasite entirely from your body, you must complete the course or you may have a recurrence of malaria.

Yes, the use of Quinine can cause dizziness along with the desired effect, but not everyone gets them. If you experience this symptom, it is recommended to avoid driving or performing any activity.

No, Quinine should not be used to treat dengue. It is used to treat malarial infections caused by the malarial parasite.

No, Quinine is not effective against typhoid. Typhoid is a bacterial infection and this medicine is an anti-parasitic medicine.

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