Piperaquine+Arterolane

Uses	Treatment of acute uncomplicated malaria infection
Therapy	Anti-Malarial
Side Effects	Headache, nausea, vomiting, fever, cough

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Molecule Description

Piperaquine+Arterolane is an anti-malarial medicine. It contains a combination of Piperaquine and Arterolane. It is used to treat uncomplicated malaria. It should be taken as directed by the doctor and in doses and duration as prescribed. It should be taken on an empty stomach. Do not miss any dose or stop taking the medicine without completing the treatment. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting Piperaquine+Arterolane.

Uses

Piperaquine+Arterolane is used in adults for the treatment of acute uncomplicated malaria infection.

Contraindications

When should one not use Piperaquine+Arterolane

If you are allergic to Piperaquine, Arterolane or any of the ingredients of Piperaquine+Arterolane.

Side effects

Common side effects of this drug are:

Headache
Dizziness
Nausea
Vomiting
Stomach pain
Fever
Cough
Loss of appetite
Weakness

Precautions and Warnings

Pregnancy

Piperaquine+Arterolane should not be used during pregnancy as there is limited safety data available in pregnant women. Thus, please consult your doctor before using this medicine, he/she may prescribe an alternate medicine.

Breast Feeding

Piperaquine+Arterolane should not be used while breastfeeding as there is limited safety data available. Thus, please consult your doctor before using this medicine.

Driving

Piperaquine+Arterolane may make you feel dizzy, you should avoid driving if you do not feel well or are unable to be alert.

Alcohol

Although there is no known interaction with alcohol and Piperaquine+Arterolane, it is essential to consult your physician if you have a habit of consuming alcohol regularly.

Other General Warnings

Talk to your doctor if

You have problems with your heart, liver or kidneys
You develop an allergic reaction after taking Piperaquine+Arterolane.
You are pregnant, think you may be or are planning a pregnancy.
You are breastfeeding
You are above the age of 60 years
You do not notice any improvement or experience any untoward side effects while on treatment, immediately contact your doctor.

Mode of Action

How Does It Work?

Piperaquine+Arterolane contains two components - Piperaquine and Arterolane, which work together in treating malaria infection. They get accumulated in the food vacuole of the parasite and undergoes various changes to form reactive species and cause prevention of heme detoxification, thereby killing the parasite.

Interactions

Interactions with other medicines

Some medicines can affect the way Piperaquine+Arterolane works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
Especially if you are taking medicines to treat your heart problems.
Other medicines such as midazolam, omeprazole, paracetamol or theophylline, enflurane, halothane and isoflurane, clarithromycin, rifampicin, carbamazepine, phenytoin, phenobarbital, St. John's wort should be used with caution along with Piperaquine+Arterolane.

Interactions with food items

Piperaquine+Arterolane should be taken on an empty stomach. Avoid consuming grapefruit juice along with this medicine.

Dosage

Overdose

Seek urgent medical attention in case you have consumed too much Piperaquine+Arterolane.

Missed a Dose

If you missed any dose of Piperaquine+Arterolane, take it as soon as you remember. However, if it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Piperaquine+Arterolane is used in adults for the treatment of acute uncomplicated malaria infection due to Plasmodium falciparum.

You must wear long-sleeved clothing and long trousers if you are outside after sunset to protect yourself from mosquito bites. You must use an insect repellent cream. You must use a mosquito net around the bed while sleeping to avoid being bitten by mosquitoes.

Do not stop taking Piperaquine+Arterolane before completing the course of treatment as your symptoms may reoccur and worsen your condition. Please speak to your doctor if you feel any discomfort while on treatment.

Inform the doctor about your detailed medical & surgical history Inform your doctor if you have heart, liver or kidney disease Inform your doctor if you are pregnant, breastfeeding or planning to have a baby Piperaquine+Arterolane may interact with other medicines, hence, inform your doctor if you are taking any other medicines including supplements or herbal products. Also, inform your doctor if you are stopping any medicine.