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Phenylephrine Hydrochloride+Chlorphenamine Maleate

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Molecule Summary

Uses
Cold, allergic rhinitis
Therapy
Cough Cold Preparation
Side Effects
Drowsiness, headache, vomiting, weakness
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Molecule Description

Phenylephrine Hydrochloride+Chlorphenamine Maleate is used for temporary relief in common cold and allergic rhinitis. It helps in improving symptoms like runny and stuffed nose, sneezing and throat irritation. Phenylephrine Hydrochloride+Chlorphenamine Maleate contains a combination of chlorpheniramine and phenylephrine as active ingredients. Chlorpheniramine is an antiallergic and phenylephrine is a decongestant. You should take this medicine as advised by your doctor for maximum benefits and avoid using it for a prolonged duration when not required.

Uses

Phenylephrine Hydrochloride+Chlorphenamine Maleate is used for the symptomatic treatment of common cold and allergic rhinitis.

Contraindications

When should one not use Phenylephrine Hydrochloride+Chlorphenamine Maleate

  • If you are allergic to chlorpheniramine or phenylephrine or any of the ingredients of Phenylephrine Hydrochloride+Chlorphenamine Maleate.
  • If you have taken medicines for brain disorders such as rasagiline in the last 14 days.
  • If you are suffering from high blood pressure or heart disease.
  • If you have diabetes, increased pressure inside the eyes (glaucoma).
  • If you are suffering from an overactive thyroid gland and breathing problems like bronchitis.
  • If you experience difficulty in urination due to an enlarged prostate gland.

Side effects

Common side effects of this drug are:

  • Drowsiness
  • Headache
  • Vomiting
  • Weakness
  • Incoordination
  • Dizziness
  • Excitation
  • Confusion
  • Increased blood pressure

Precautions and Warnings

Pregnancy

Pregnancy

Phenylephrine Hydrochloride+Chlorphenamine Maleate may affect the pregnancy and it should be used only if prescribed by a doctor. Your doctor will tell you about the use of this medicine after assessing the benefits over risks. Do not self medicate with this medicine for cough and cold.

Breast Feeding

Breast Feeding

A component of Phenylephrine Hydrochloride+Chlorphenamine Maleate passes into the breastmilk. So, it is recommended not to consume it unless prescribed by your doctor.

Driving

Driving

You may experience drowsiness, dizziness or blurred vision after taking Phenylephrine Hydrochloride+Chlorphenamine Maleate. Be cautious while driving or operating any machinery.

Alcohol

Alcohol

Alcohol intake can make you feel more drowsy or sleepy. It is advised to avoid alcohol consumption during the treatment with Phenylephrine Hydrochloride+Chlorphenamine Maleate.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are already taking medicines for psychiatric illness, as it can enhance drowsiness
  • You are experiencing drowsiness, nervousness.
  • You don't feel any improvement in your symptoms within a week.
  • You are pregnant or breastfeeding.
  • You have asthma or any airway obstruction problems.
  • You have a kidney or liver disease.
  • You have a history of fits or seizures.
  • You have a history of tumour in the adrenal gland.
  • You have a blockage in your stomach and intestine.

Mode of Action

How Does It Work?

  • Phenylephrine Hydrochloride+Chlorphenamine Maleate works by the combined action of its two components chlorpheniramine and phenylephrine. Chlorpheniramine acts by blocking the action of histamine a natural substance produced by the body during an allergic reaction and improves allergic symptoms like sneezing, watery eyes, throat irritation, etc.
  • Phenylephrine acts as a vasoconstrictor, it shrinks or constricts the blood vessels in the nasal passage and improves congestion.

Interactions

Interactions with other medicines

  • Medicines used to treat brain disorders or psychiatric illness should not be used with Phenylephrine Hydrochloride+Chlorphenamine Maleate as it can lead to a risk of heart-related side effects or increased blood pressure.
  • Phenylephrine Hydrochloride+Chlorphenamine Maleate can reduce the effectiveness of high blood pressure medicines and can increase blood pressure abruptly.
  • Phenylephrine Hydrochloride+Chlorphenamine Maleate should not be taken along with medicines used to treat heart failures such as digoxin as it can increase the risk of irregular heartbeat or heart attack.
  • Phenytoin and ergot containing medicines should not be consumed along with Phenylephrine Hydrochloride+Chlorphenamine Maleate as it can lead to toxicity.
  • Other medicines like medicines to induce sleep or anti-anxiety medicines and certain painkillers should be used with caution as they can induce sedation.
  • Discuss it with your doctor about any other medicine, herbal preparation and supplements you are taking currently to avoid any possible drug interactions.

Dosage

Overdose

Symptoms of overdose of Phenylephrine Hydrochloride+Chlorphenamine Maleate may include irregular heartbeat, fits or you may sometimes pass out. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of Phenylephrine Hydrochloride+Chlorphenamine Maleate, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Take Phenylephrine Hydrochloride+Chlorphenamine Maleate as per the prescribed dosage duration by your doctor as this medicine can cause dizziness or sleepiness. So do not give this medicine to induce sleep to the children.

Do not consume alcohol or any other cough medicines along with Phenylephrine Hydrochloride+Chlorphenamine Maleate. It can lead to excessive dizziness or sleepiness. Caution is recommended while driving or operating machinery.

Phenylephrine Hydrochloride+Chlorphenamine Maleate is not recommended for patients having high blood pressure as it can increase your blood pressure abruptly and can also reduce the effectiveness of high blood pressure medicines.

No, Phenylephrine Hydrochloride+Chlorphenamine Maleate should not be used in children below 6 months of age. Also, you should always consult a child specialist before giving any medicine to your baby as their organs are very delicate and sensitive.

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