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Pentazocine

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Molecule Summary

Uses
Moderate to severe pain
Therapy
Analgesic For Severe Pain
Side Effects
Headache, nausea, dizziness, vomiting, drowsiness, dry mouth
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Molecule Description

Pentazocine is a prescription pain medicine (an opioid analgesic) used to relieve moderate to severe pain.

Uses

  • Moderate to severe pain

Contraindications

When should one not use Pentazocine

  • If you have known allergy to any of the ingredients present in the medicine
  • If you are taking medications that are classified as Monoamine Oxidase Inhibitors (MAOIs) such as moclobemide or similar medicines like linezolid
  • If you are taking medicine such as pimozide for mental disorder

Side effects

Common side effects of this drug are:

  • Headache
  • Nausea
  • Dizziness
  • Vomiting
  • Drowsiness
  • Dry mouth

Precautions and Warnings

Pregnancy

Pregnancy

No, Pentazocine is not safe to be taken during pregnancy as it is known to cause problems in the newborn when taken during pregnancy. However, if you are pregnant, or planning to become pregnant, consult your doctor before starting any medication.

Breast Feeding

Breast Feeding

Avoid taking Pentazocine while breastfeeding as it is found to be excreted in breast milk. If your child is sleeping more than usual, or any sign of breathing difficulty is noticed, or is unable to suckle, immediately consult your doctor.

Driving

Driving

No, it is not safe to drive when taking Pentazocine as it is known to cause impairment of mental and

Driving

Driving

physical abilities required while driving a car.

Driving

Driving

It may cause sleepiness, dizziness, confusion, forgetfulness and affect your judgement and thinking ability and hence not suggested to drive a car when under this medication.

Alcohol

Alcohol

No, alcohol must be avoided with Pentazocine as it causes all the side effects of an overdose which

Alcohol

Alcohol

can be fatal.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have liver, kidney, or heart problems
  • You have epilepsy or any history of fits or seizures
  • You have eye problem such as glaucoma
  • You have diabetes
  • You have history of bleeding disorders or taking any medicine that may make your blood thin
  • You are on a low sodium diet or taking medicine for hypertension

Mode of Action

How Does It Work?

Pentazocine is an opioid pain medicine. It works on opioid receptors in the brain and spinal cord to change how pain is felt.

Interactions

Interactions with other medicines

  • Seek medical advice before taking Pentazocine if you are taking:
  • Medicines to treat severe pain (tramadol)
  • Medicines to reduce the risk of bleeding (warfarin)
  • Medicines for migraine (sumatriptan, almotriptan)
  • Medicines for high blood pressure treatment (diltiazem)
  • Antibiotics (erythromycin)
  • Medicines for fits or epilepsy (phenytoin, carbamazepine)
  • Medicines for the treatment of tuberculosis (rifampicin)
  • Other medicines for managing depression (buprenorphine)
  • Medicines for Parkinson's disease such as procyclidine

Interactions with food items

  • Pentazocine may interact adversely with:
  • St. John's Wort (herbal medicine for depression)
  • Tryptophan containing dietary supplements (milk, cheese, oats)

Dosage

Overdose

Symptoms of an overdose of Pentazocine can be fatal and include CNS depression leading to

Missed a Dose

Pentazocine is generally prescribed to be taken once daily with food at night before bedtime. If you

Frequently Asked Questions (FAQs)

Pentazocine is not meant to be given to children and adolescents below 18 years of age. Hence, avoid giving this medicine to children.

No, you should not stop taking Pentazocine suddenly without consulting your doctor as it may cause symptoms of withdrawal like mood changes, depression, anxiety, headache, disturbed sleep, confusion and

sweating.

After taking Pentazocine if you experience palpitations or irregular heartbeat or any discomfort that

Is worsening or not going away, immediately consult your doctor or the nearest emergency hospital.

Some patients after taking this medicine may feel that they are unable to sit or stand still and have become too restless. Consult your doctor if you feel any of these symptoms after taking Pentazocine.

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