Oxybutynin
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Molecule Summary
| Uses | Overactive bladder |
| Therapy | Drugs For Urinary Incontinence |
| Side Effects | Headache, dizziness, nausea |
Medicines
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Molecule Description
Oxybutynin is used for the treatment of overactive bladder. It is used to relieve urinary symptoms like frequent urination, the urgency to urinate and uncontrolled urination. Oxybutynin works by acting on the muscles of the bladder and controlling the overactivity of the bladder. Take this medicine in a dose and duration prescribed by your doctor. Avoid alcohol and caffeinated drink, as they can worsen your symptoms. Be cautious while driving or operating the machine as this medicine may cause dizziness. Before starting Oxybutynin inform your doctor about all other medicines, herbal products and over-the-counter medicines you are consuming.
Uses
Oxybutynin is used in the treatment of frequency and urgency of urination due to overactivity of the bladder (Neurogenic bladder disorder).
Contraindications
When should one not use Oxybutynin
- If you are allergic to oxybutynin or any of the other ingredients of Oxybutynin.
- If you have a condition called muscle weakness (myasthenia gravis) and increased pressure in the eye (glaucoma).
- If you have a problem in your heart and kidney (responsible for frequent urination at night).
- If you feel that your stomach or intestine is not working properly.
- If you are suffering from inflammation in the intestine (ulcerative colitis).
Side effects
Common side effects of this drug are:
- Headache
- Dizziness
- Sleepiness
- Diarrhoea
- Nausea
- Vomiting
- Dry skin
- Difficulty in urination
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You are an elderly person or you are giving this medicine to a child, this medicine should be used with caution.
- You have a kidney or liver problem.
- You are suffering from an illness called autonomic neuropathy (affecting the nerves).
- You have a history of an overactive thyroid gland (hyperthyroidism), heart disorder.
- You are suffering from high blood pressure or an enlarged prostate gland.
- You have a stomach/intestinal disorder, such patients should use this medicine carefully.
- You feel heart problems like irregular or fast heartbeat, heart failure, high blood pressure or enlarged bladder (prostate) problems.
- You experience any mental disorders like hallucination, sleepiness, confusion, aggression. The doctor should stop the treatment immediately.
- It may reduce the amount of saliva production which can lead to tooth decay or fungal infection of the mouth. So the doctor may advise taking special care in your oral hygiene.
- You may develop a risk for heat prostration due to decreased sweating if used in high-temperature conditions.
- You have an indigestion problem and you are simultaneously taking medicines like bisphosphonates that can cause or worsen oesophagitis (swelling in food pipe).
Mode of Action
How Does It Work?
Oxybutynin acts by stopping the sudden contraction of bladder muscles and makes the muscles relax, which leads to control in the release of urine.
Interactions
Interactions with other medicines
- Oxybutynin may interact with other medicines and produce an altered response. Please tell your doctor if you are using any other medicines, over-the-counter medicines (that you buy without a prescription) and herbal preparations.
- Few medicines which may affect the activity of Oxybutynin are Amantadine, Levodopa, Biperiden to treat Parkinson's disease, Phenothiazines, Butyrophenones, Clozapine to treat brain disorders, Quinidine, Digoxin to treat heart problems, Dipyridamole to treat blood clotting problems.
- Concomitant use of antibiotics like Ketoconazole, Itraconazole, Erythromycin to treat bacterial and fungal infections can inhibit the action of this medicine.
- It can oppose the effect of Metoclopramide or Domperidone to treat nausea and vomiting.
- Other medicines that should be used with caution are atropine and cholinesterase inhibitors to treat Alzheimer's disease.
Dosage
Overdose
Symptoms of an overdose may include restlessness, excitement, flushed, dizziness, fast heartbeat, breathing problem and numbness, paralysis and coma. If you think you have taken an overdose of Oxybutynin and feel such symptoms contact your doctor immediately.
Missed a Dose
- If you have missed any dose of Oxybutynin take it as soon as you remember.
- If it's time for your next dose then skip the missed dose and continue with your regular dose schedule.
- Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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References:
- Oxybutynin Hydrochloride 2.5mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. [cited 2 Jun 2026].
- Oxybutynin Hydrochloride 2.5mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. [cited 2 Jun 2026].
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 4634, Oxybutynin.[cited 2 Jun 2026].
- Dwyer J, Tafuri SM, LaGrange CA. Oxybutynin. [Updated 2023 Aug 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing;.[cited 2 Jun 2026].
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