Noscapine
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Molecule Summary
| Uses | Short term treatment of dry cough |
| Therapy | Cough Cold Preparation |
| Side Effects | Nausea, vomiting, increased heart rate, loss of appetite, dilated pupils, decreased coordination, drowsiness |
Medicines
available
19k pincodes
Molecule Description
Noscapine is a medication that primarily aids in the treatment of cough.
Uses
- Treatment of dry (non-productive) cough
Contraindications
When should one not use Noscapine
- If you are hypersensitive to noscapine or other ingredients of this medicine.
- If you are pregnant.
- If you have been diagnosed with high blood pressure.
- If you have a history of alcoholism.
- If you suffer from liver dysfunction.
- If you have been diagnosed with peptic ulcer disease.
- If you have had a cardiac arrest.
- If you have been diagnosed with thyroid disorders.
Side effects
Common side effects of this drug are:
- Nausea and vomiting
- Increased heart rate
- Loss of appetite
- Dilated pupils
- Decreased coordination
- Drowsiness
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You experience persistent or worsening side effects.
- Your condition does not improve.
- You conceive or are planning a pregnancy during the course of the medication.
- You are taking any herbal medicines or supplements.
Mode of Action
How Does It Work?
Noscapine works on the brain by action on particular receptors called sigma receptors. Studies in animal subjects have shown that by activating this receptor, it produces cough-suppressing (antitussive) effects.
Interactions
Interactions with other medicines
- The use of Noscapine along with alcohol and other CNS depressants is contraindicated.
- The concurrent use of noscapine with a group of medications called MAOIs (monoamine oxidase inhibitors) is contraindicated.
- It should not be used alongside medications that prevent clotting of blood like warfarin, as it can increase this effect. This can result in bleeding problems.
Interactions with food items
- Noscapine is recommended to be taken before food on an empty stomach.
- Drink plenty of fluids.
- Avoid consuming grapefruit or its juice while taking this medicine, as it may cause unwanted effects by decreasing the metabolisation of noscapine.
Dosage
Overdose
Effects of Noscapine overdose are similar to that of alcohol intoxication. They can present with mild sedation, poor coordination, slurring of speech, difficulty in walking/balancing, vomiting, insomnia. Overdoses with very high quantities of this medicine can be life-threatening. In case of a suspected overdose, immediately rush the patient to the nearest tertiary care hospital for emergency management.
Missed a Dose
If you miss a dose of Noscapine, it is advised to take it as soon as possible. If it is almost time for the next dose, it is recommended to skip the missed dose and go back to the regular schedule. Do not double the dose of the medicine.
Frequently Asked Questions (FAQs)
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