Nitroglycerin / Glyceryl Trinitrate

Uses	Chest pain (angina)
Therapy	Anti-Anginal
Side Effects	Headache, dizziness, drowsiness, nausea, vomiting

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Molecule Description

Nitroglycerin / Glyceryl Trinitrate is a medication used to prevent chest pain caused by blockages in the blood vessels that supply blood to the heart. It acts as a vasodilator to widen and relax the heart's blood vessels. This reduces pressure on the heart, making it easier to pump blood. You should take this medicine exactly as your doctor advised. Take this medicine at the same time every day to gain optimum benefits. You should never stop taking this medicine on your own without consulting your doctor, as it may increase your risk of heart-related complications. Inform your doctor about all your medical conditions and medication history.

Uses

Nitroglycerin / Glyceryl Trinitrate is used for the prevention of chest pain (angina pectoris) due to blockages in the vessels that supply blood to the heart (coronary artery disease).

Contraindications

When should one not use Nitroglycerin / Glyceryl Trinitrate

If you are allergic to glyceryl trinitrate/nitroglycerin or any other component of Nitroglycerin / Glyceryl Trinitrate.
If you have a condition of severely low red blood cells called anaemia.
If you recently had head trauma or brain haemorrhage resulting in increased pressure within the brain.
If you have increased pressure in the eye called glaucoma.
If you are taking medicines called sildenafil, tadalafil, or vardenafil they are used for the treatment of erection problems.
If your doctor has told you that you have a heart condition for which this medicine is not suitable.

Side effects

Common side effects of this drug are:

Headache
Nausea
Vomiting
Dizziness
Drowsiness

Precautions and Warnings

Pregnancy

There is limited information about the effect of Nitroglycerin / Glyceryl Trinitrate during pregnancy. You should not take this medicine unless prescribed by your doctor after assessing the need and the risk.

Breast Feeding

No information is available if Nitroglycerin / Glyceryl Trinitrate passes into human breast milk. You should not take this medicine unless recommended by your doctor after assessing the need and the risk.

Driving

Nitroglycerin / Glyceryl Trinitrate may cause dizziness. If you experience any such effects after taking this medicine that may affect your ability to drive safely, it is suggested to avoid driving.

Alcohol

No, alcohol should not be consumed while on treatment with Nitroglycerin / Glyceryl Trinitrate as it may lead to side effects like dizziness, headache, and drowsiness.

Other General Warnings

Talk to your doctor if

You have liver, heart, or kidney problems.
You have a low body temperature (hypothermia).
You have poor nutrition due to an unbalanced diet or digestion problems.
You have abnormally low levels of oxygen in the blood.
You have or had any condition affecting the blood supply to the brain.
You have low blood pressure, low blood volume, or conditions that lower blood volume in the heart.

Mode of Action

How Does It Work?

Nitroglycerin / Glyceryl Trinitrate is a nitrate that acts by releasing nitric oxide which relaxes the blood vessels. This reduces the pressure on the heart and decreases the oxygen demand of the heart thereby preventing angina attack (chest pain).

Interactions

Interactions with other medicines

Some medicines can affect the way Nitroglycerin / Glyceryl Trinitrate works or Nitroglycerin / Glyceryl Trinitrate itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
Particular care should be taken if you are taking medicines to treat high blood pressure, heart failure, high/abnormal cholesterol levels, blood clots, erection problems, other vasodilators, painkillers, immunomodulatory medicines, or medicines for brain-related disorders.

Interactions with food items

Nitroglycerin / Glyceryl Trinitrate can be taken with or without food.

Dosage

Overdose

Symptoms of overdose of Nitroglycerin / Glyceryl Trinitrate include headache, dizziness, drowsiness, nausea, vomiting, and low blood pressure. If you think you had too much of this medicine, reach out to the doctor immediately.

Missed a Dose

If you have missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

No, you should never stop taking Nitroglycerin / Glyceryl Trinitrate. Abrupt stopping of this medicine may result in angina attack (sudden chest pain) and other conditions resulting in heart attack and difficulty in breathing. Your doctor will gradually reduce the dose of the medicine before stopping the medicine completely. Talk to your doctor for more advice.

This depends on the form of the medicine prescribed. Use it exactly as directed by your doctor or pharmacist.

No, you should not take sildenafil or similar medicines for erection problems along with Nitroglycerin / Glyceryl Trinitrate as it may cause a severe blood pressure-lowering effect. Taking both medicines together may result in life-threatening conditions.

No, Nitroglycerin / Glyceryl Trinitrate is not a blood thinner medicine. This medicine acts by relaxing the blood vessels, thereby decreasing the blood pressure, in the condition of chest pain (angina).

No, Nitroglycerin / Glyceryl Trinitrate may not be effective to treat heart attacks. During the episode of heart attack, sublingual medicines are most effective as they have a faster onset of action. Talk to your doctor for more information.

Nitroglycerin / Glyceryl Trinitrate is used for the prevention of chest pain (angina pectoris) due to blockages in the vessels that supply blood to the heart (coronary artery disease).

Nitroglycerin / Glyceryl Trinitrate can be taken with or without food. However, you should take this medicine exactly as recommended by your doctor. Take this medicine at the same time every day to gain optimum benefits.