Modafinil is a medicine that stimulates the brain and is used to treat patients who sleep excessively and at inopportune times....
Precautions and Warnings
Mode of Action
Uses of Modafinil
Improving wakefulness in patients with excessive sleepiness -
difficulty to stay awake and falling asleep at improper times (e.g. at morning or evening), a condition called narcolepsy
Sometimes, excessive sleepiness may be associated with extreme muscle weakness (the patient may collapse but remains conscious) combined with intense emotions such as laughter, crying, feeling scared – a condition called cataplexy...
Modafinil can be given for excessive sleepiness with or without cataplexy
Contraindications of Modafinil
When should one not use Modafinil
Allergy to Modafinil or any of its component
Severe, high, uncontrolled blood pressure
Side effects of Modafinil
Common side effects of this drug are:
Feeling very tired, sleepy or difficulty sleeping (insomnia)
Fast heartbeats, which you can feel
Stomach problems – pain, feeling sick, loss of appetite, indigestion, diarrhea or loose motions
Weakness, numbness or tingling of hands and feet (‘pins and needles’)
Inform your doctor immediately if you notice any such symptoms
Precautions and Warnings of Modafinil
Can I take Modafinil during pregnancy?
Modafinil should not be used in pregnancy as it is known to cause harmful effects on the baby.
Can I take Modafinil while breastfeeding?
Modafinil is secreted in breast milk and may harm the newborn baby, hence should not used during breastfeeding.
Can I drive if I have consumed Modafinil?
As Modafinil is taken for excessive sleep, be aware that it will not drastically improve your symptoms but will only decrease the intensity. Hence, it is generally not advised to drive in such conditions.
Can I consume alcohol with Modafinil?
Alcohol causes drowsiness and may interfere with the actions of Modafinil and is not recommended.
Other General Warnings
Talk to your doctor if
If you are allergic to Modafinil or have any other allergies
If you have any heart problems or high blood pressure
Mood swings (severe depression, low mood, psychosis, extreme highs or mania), anxiety, hallucinations (loss of contact with reality)
If you have any kidney or liver problems (because you will need to take a lower dose)
If you had any issues with alcohol or substance misuse in the past
Mode of Action of Modafinil
How Does It Work?
Modafinil works by regulating the action of certain substances in the brain by increasing the levels of certain elements called Dopamine and orexins that transmits signals in the brain (neurotransmitters) and promotes wakefulness
Decreased levels of these substances will make it difficult for a person to stay awake...
Certain medicines used to treat HIV/ AIDS (Ritonavir, Indinavir)
Anti-depressant or anti-anxiety medicines (Amitryptiline, Citalopram, Fluoxetine, Diazepam)
Blood-thinning agents (Warfarin)
Certain blood pressure medicines (Amlodipine, Verapamil, Propranolol)
Cholesterol reducing agents (Statins)
Cyclosporine (an immunosuppressant)
Omeprazole (reduces stomach acid)
Interactions with food items
Modafinil does not interact with food and can be taken before or after meals. Usually, it is taken in the morning.
Dosage of Modafinil
Accidental overdose may not be life-threatening and may cause sleeplessness or restlessness. Extreme doses may cause psychotic symptoms such as agitation, disorientation, feel something which is not there (hallucinations), etc. if you experience any such symptoms, inform your doctor immediately and seek medical attention....
Missed a Dose
If you miss a dose, then skip it. Do not take a double dose.
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