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Misoprostol

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Molecule Summary

Uses
Gynaecological conditions under medical supervision
Therapy
Drugs Acting On Uterus
Side Effects
Nausea, abdominal cramps, uterine cramping, heavy bleeding
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Molecule Description

Misoprostol is strictly used under medical supervision for the prescribed clinical condition only. This medication acts by increasing uterine contractions. Common side effects of Misoprostol include infection, nausea, vomiting, diarrhoea, abdominal cramps, uterine cramping, and heavy bleeding. If these side effects appear serious, let your gynaecologist know. Post medication vaginal bleeding may last for 10-12 days. Inform your gynaecologist if it continues after 12 days or if you experience unbearable cramps. Before starting Misoprostol, tell your doctor if you have ever had an ectopic pregnancy or used an intrauterine contraceptive device. Avoid Misoprostol if you are nursing your baby.

Uses

Misoprostol is used for the management of gynaecological conditions only when prescribed by your doctor.

Contraindications

When should one not use Misoprostol

  • If you are allergic to misoprostol or other constituents in this medicine.
  • If your pregnancy is ectopic.
  • If you have anaemia.
  • If you are suffering from heart disease or diabetes.
  • If you are using an intrauterine device like copper-T.
  • If you have chronic adrenal failure.
  • If you have unexplained vaginal bleeding or have a hemorrhagic disorder.

Side effects

Common side effects of this drug are:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal cramps
  • Uterine contractions
  • Heavy menstrual bleeding
  • Infection

Precautions and Warnings

Pregnancy

Pregnancy

It is exceedingly risky to use Misoprostol while pregnant. Research on pregnant women and animals has revealed severe risks to the growing infant. In case you are pregnant and have already taken this medicine, seek medical advice immediately.

Breast Feeding

Breast Feeding

It is not safe to use Misoprostol when nursing. The medication can cause toxicity in the baby.

Driving

Driving

While using Misoprostol, your attentiveness may be reduced. Misoprostol frequently causes drowsiness. You should avoid driving if you're taking this medication.

Alcohol

Alcohol

It's not safe to take Misoprostol with alcohol. While using this medication, you should avoid or limit your alcohol use. After taking Misoprostol, avoid jobs that need mental focus, such as operating machinery. Taking alcohol and Misoprostol together can cause dizziness, fatigue, and difficulty concentrating.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You've ever had an ectopic pregnancy.
  • You have an intrauterine device.
  • You must not smoke while taking Misoprostol, as heavy smoking can have adverse effects.
  • You must not use it after the 9th week of pregnancy (up to 63 days after the first day of your last menstrual period).
  • You may experience vaginal bleeding after taking Misoprostol, which lasts for around 12 days. If you experience significant bleeding or severe abdominal pain, call your doctor right away.
  • You must take Misoprostol within 63 days of the beginning day of your last menstrual period. An unfinished MTP might have medical consequences.

Mode of Action

How Does It Work?

Misoprostol efficiently causes uterine contractions that lead to the expulsion of the fetus.

Interactions

Interactions with other medicines

  • The combination of Dinoprostone and Misoprostol is not safe because it increases the risk of vaginal bleeding.
  • Magnesium-containing antacids and Misoprostol: when these medications are combined, the risk of medicine-induced diarrhoea is very significant. Before using Misoprostol, tell your doctor if you're taking any antacids.

Interactions with food items

  • While using Misoprostol, avoid consuming grapefruit juice because it may increase the risk of its side effects.

Dosage

Overdose

Follow your gynaecologist's directions for Misoprostol dosage and duration. Double-check the label before usage. In the event of an overdose, seek emergency medical attention or contact a doctor.

Missed a Dose

Contact the doctor, if you miss a dose of Misoprostol. Do not double up doses of Misoprostol without consulting the doctor.

Frequently Asked Questions (FAQs)

If you have liver disease, consult your doctor before using Misoprostol.

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