Menotrophin

Uses	Infertility in women, to increase sperm count in men
Therapy	Drugs For Infertility
Side Effects	Headache, nausea, vomiting, abdominal pain, injection site reactions

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Molecule Description

Menotrophin is a highly purified mixture of two hormones namely luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Both LH and FSH occur naturally in men as well as women and are involved in normal reproductive functions. Menotrophin is extracted from the urine of post-menopausal women.

Uses

Menotrophin is used for the treatment of infertility in women. And in men, it is used to increase sperm count.

Contraindications

When should one not use Menotrophin

If you have an allergy to menotrophin or any other component of this medicine.
If you have a pituitary gland tumour.
If you are suffering from tumour of the hypothalamus.
If you are suffering from tumour of the womb (uterus), ovaries or breasts.
If you have fluid-filled sacs (cysts) in your ovaries (not due to PCOD).
If you have noticed unusual vaginal bleeding.
If your menstrual periods have stopped too early (premature menopause).
If you have any abnormalities related to your reproductive organs (womb, fallopian tubes, ovaries or cervix).
If you have got your womb (uterus) removed (hysterectomy).
If you have non-cancerous tumours in your womb (fibroid).
If you are a pregnant or breastfeeding mother.
If you have cancer of the prostate gland or testicles.

Side effects

Common side effects of this drug are:

Allergic reaction like rashes, swelling in and around the mouth, difficulty in breathing
Headache
Sickness (nausea)
Pain in the lower abdomen
Pain at the injection site
Swelling in the abdominal region
Vomiting
Weakness, unsteadiness
Abdominal pain and swelling
Weight gain
Diarrhoea
Decrease in urination
Formation of blood clots in blood vessels

Precautions and Warnings

Pregnancy

Use of Menotrophin is strictly contraindicated during pregnancy.

Breast Feeding

Menotrophin should not be given to a breastfeeding woman. Its use is contraindicated for nursing mothers.

Driving

Menotrophin is not supposed to affect your driving abilities. You may drive if you feel alert and comfortable.

Alcohol

Alcohol is not known to interact with this medicine. However, if you consume alcohol too often discuss it with your doctor.

Other General Warnings

Talk to your doctor if

You have any problem or tumour related to the thyroid gland, adrenal glands, pituitary gland or hypothalamus.
Your prolactin levels are deranged.
You experience any of the following symptoms of excessive ovarian stimulation after starting this treatment: abdominal pain and swelling, weight gain, diarrhoea, vomiting, collection of fluid in the lower abdominal region, decrease in urination, the formation of blood clots in blood vessels, twisting pain in ovaries (ovarian torsion).

Mode of Action

How Does It Work?

Menotrophin is used in both men and women as it has actions equivalent to both luteinizing hormone and follicle-stimulating hormone. It helps in improving the reproductive function by facilitating the release of eggs in females and increasing sperm counts in males.

Interactions

Interactions with other medicines

If Menotrophin is given along with clomiphene citrate, the action of this medicine is expected to increase.
Tell your doctor about all the medicines or herbal supplements that you are taking before starting this treatment.

Dosage

Overdose

Menotrophin will be given by a doctor or nurse thus chances of overdose are unlikely. However, if you experience any discomfort or specific symptoms inform your doctor or reach out to the nearest hospital.

Missed a Dose

It is unlikely that the dose of Menotrophin will be missed if you are monitored in a healthcare set up. However, if you have missed taking any dose of Menotrophin inform your doctor or nurse immediately.

Frequently Asked Questions (FAQs)

Yes Menotrophin may cause some sickness or vomiting. In case you experience the symptoms too often, your doctor may prescribe you some medicine for symptomatic relief.

Yes Menotrophin can be given to both men and women but only when your doctor has prescribed it.