Lisinopril is an ACE inhibitor (ACE stands for Angiotensin Converting Enzyme).
Uses of Lisinopril
- To treat high blood pressure (hypertension)
- To treat heart failure (congestive heart failure)
Contraindications of Lisinopril
When should one not use Lisinopril
- Do not take this medicine if you have any allergy to Lisinopril or other ACE inhibitors such as Captopril if you have diabetes
- Also, this medicine is not be used in patients who are taking blood lowering medication containing Aliskiren and medicines used to treat long-time heart failure like Valsartan
Side effects of Lisinopril
Common side effects of this drug are:
- Allergic reaction such as difficulty in breathing, swelling tongue or difficulty in swallowing
- Increased in liver enzymes
- Yellowing of skin or eye (jaundice)
- Low blood pressure
Precautions and Warnings of Lisinopril
Can I take Lisinopril during pregnancy?
Do not use Lisinopril if you are pregnant. If you are pregnant, stop taking this medicine and tell your doctor immediately. This medicine can cause injury or even death of the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking Lisinopril.
Can I take Lisinopril while breastfeeding?
Not much information is available on the use of Lisinopril during breastfeeding. Hence Lisinopril is not recommended for mothers who are breastfeeding. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant.
Can I drive if I have consumed Lisinopril?
While taking Lisinopril, you may feel dizzy or tired. If this happens, do not drive.
Can I consume alcohol with Lisinopril?
Alcohol can also lower your blood pressure and may increase the risk of specific side effects. Avoid alcohol.
Other General Warnings
Talk to your doctor if
- You have low blood pressure (hypotension)
- You are dehydrated due to treatment with Diuretic medicine
- You suffer from abnormal functioning of the heart
- You have had a stroke or mini-stroke (also known as Transient Ischaemic Attack (TIA))
- You suffer from kidney disease, improper functioning of the kidneys or narrowing (stenosis) of the blood vessels to the kidney
- You have diabetes
- You have high potassium level in your blood (hyperkalaemia)
Mode of Action of Lisinopril
How Does It Work?
ACE inhibitors block the enzyme called Angiotensin Converting Enzyme and thereby lowers the blood pressure by widening the blood vessels. This allows the blood to flow more efficiently and reduces the effort needed to pump blood around the body.
Interactions of Lisinopril
Interactions with other medicines
Lisinopril may interact with medicines such as Aspirin, Aliskiren, Non-Steroidal Anti-Inflammatory Drugs like Ibuprofen and Indomethacin, Diuretics like Furosemide, Torsemide and antidepressants.
Interactions with food items
If you are on treatment with Lisinopril, then avoid supplements containing potassium as they interact with it and increase the risk of side effects.
Dietary Restrictions of Lisinopril
No information is available on dietary restrictions while you are taking Lisinopril, consult your doctor or pharmacist for further information.
Dosage of Lisinopril
Symptoms of overdose include low blood pressure, shock (a dangerous decrease of blood pressure which if untreated, may lead to collapse or loss of consciousness), kidney failure, changes in blood salts which may be seen in blood tests, difficulty in breathing, increased or decreased heartbeat, dizziness, anxiety and cough. Consult doctor immediately if you suspect overdose.
Missed a Dose
Take the missed dose as early as you remember. If it is almost the time for your next dose, skip the missed dose. Do not take extra medicine to compensate for the missed dose.
Frequently Asked Questions (FAQs)
Q: Why should we not take potassium-rich foods or potassium supplements while taking this medicine?
A: Lisinopril is known to cause Hyperkalemia, a condition where there is an increase in potassium levels, hence potassium-rich foods or potassium supplements are avoided while taking this medicine.
Q: Lisinopril is avoided in which kidney conditions?
A: If you suffer from kidney disease or improper functioning of the kidneys. If you suffer from narrowing (stenosis) of the blood vessels to the kidneys.
- EMA. lisinopril. [Accessed 8 Sep 2019] (online)
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Lisinopril. [Updated 2019 Feb 28]
- Medscape. lisinopril. [Accessed 8 Sep 2019] (online)
- Webmd. lisinopril. [Accessed 8 Sep 2019] (online)
- CDSCO. lisinopril. [Accessed 27 Sep 2019] (online)
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)
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