Levosulpiride+Pantoprazole

Uses	GERD
Therapy	Antacid And Anti-Reflux
Side Effects	Headache, diarrhoea, nausea, vomiting, flatulence

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Molecule Description

Levosulpiride+Pantoprazole is a combination medicine used for the prevention of acid reflux from the stomach to the food pipe and prevention of the production of excess acid in the stomach. It consists of two active ingredients, pantoprazole and levosulpiride. Pantoprazole reduces acid production in the stomach. Levosulpiride prevents acid reflux in the food pipe from the stomach by increasing movement of the stomach and bowel. Do not use it if you are pregnant or a lactating mother or if you are allergic to any of its components. Levosulpiride+Pantoprazole should only be used under medical supervision.

Uses

Levosulpiride+Pantoprazole is used to treat GERD (gastro-oesophageal reflux disease), not responding to Pantoprazole alone. It helps in relieving symptoms such as heartburn, chest discomfort or acidity.

Contraindications

When should one not use Levosulpiride+Pantoprazole

If you are allergic to pantoprazole and levosulpiride or any of the other ingredients of Levosulpiride+Pantoprazole.
If you have severe kidney disease or liver disease.
If you are pregnant or breastfeeding.
If you have an obstruction in your bowel or have blood in vomit or stool.
If you have a tumour of the adrenal gland called pheochromocytoma.
If you have a seizure disorder (epilepsy) or have an abnormally elevated mood (mania).
If you have prolactin hormone-secreting tumour of the pituitary gland (prolactinoma) and breast cancer present together.

Side effects

Common side effects of this drug are:

Headache
Diarrhoea
Nausea
Vomiting
Pain in stomach
Flatulence
Dizziness
Joint pain

Precautions and Warnings

Pregnancy

It is not recommended to be used during pregnancy due to limited information available on its safety. Consult your doctor before taking this medicine if you are pregnant or think you may be pregnant.

Breast Feeding

Components of this medicine are known to be excreted in milk. This medicine should be avoided if you are breastfeeding.

Driving

This medicine does not affect your ability to drive or to use machinery, however if you experience side effects like dizziness, you should avoid driving or using machines.

Alcohol

Consuming alcohol while on this medicine can increase sleepiness. Avoid alcohol consumption while on this medicine.

Other General Warnings

Talk to your doctor if

You have any pre-existing medical condition such as kidney or liver disorder, any kind of heart disease etc.
You have a rash over the skin.
You are taking this medicine for a longer duration.
You have tiredness, seizures, irregular heartbeat or muscle spasm.
Your doctor tells you that you have a low vitamin B12 level in your blood.
You have to undergo a urine test.

Mode of Action

How Does It Work?

Levosulpiride works by preventing acid reflux in the food pipe from the stomach by increasing movement of the stomach and bowel.
Pantoprazole works by inhibiting a pump called the proton pump in the stomach wall, responsible for the secretion of stomach acids for digestion and hence leads to reduced acid production.

Interactions

Interactions with other medicines

Certain medicines affect the way Levosulpiride+Pantoprazole works or this medicine itself affects the action of other medicines taken at the same time. Inform the physician about the medicines, supplements or herbals you take or might take to avoid possible interaction.
Especially if you are consuming medicines like antibiotics, antifungals, anti-HIV medications, blood thinners, immune-suppressant medicines like methotrexate, brain and mood-related medicines etc.

Interactions with food items

It is recommended to take Levosulpiride+Pantoprazole on an empty stomach, preferably 30 minutes before a meal. Limit the intake of high-fat and greasy foods.

Dosage

Overdose

Symptoms of overdose include fits, loss of balance, difficulty in sleeping, etc. If you have taken too much of this medicine, contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed taking any dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose at the usual time. Do not take a double dose.

Frequently Asked Questions (FAQs)

Levosulpiride+Pantoprazole can cause loose motions as a side effect of using this medicine.

Levosulpiride+Pantoprazole should be taken on an empty stomach, preferably 30 minutes before a meal. It should not be taken with food or just after food as the presence of food in the stomach causes a decrease in the action of this medicine.

Inform your doctor about any pre-existing medical condition such as kidney or liver disorder or heart disease, if you are pregnant or breastfeeding, and about all medicines you are taking. Heartburn and chest pain mimic the symptoms of a heart attack. If you have chest pain that spreads to the jaw, shoulders, arms, back and you feel light-headed and anxious, seek medical help.

No, Levosulpiride+Pantoprazole is not a painkiller medicine. It is an anti-reflux medicine used to treat and prevent acid reflux.

Levosulpiride+Pantoprazole is used to treat GERD (gastro-oesophageal reflux disease), when not responding to Pantoprazole alone. It helps in relieving symptoms such as heartburn, chest discomfort or acidity.

Although both medicines are used to treat GERD, they have different ingredients. Pantoprazole+Domperidone contains pantoprazole and domperidone, while Levosulpiride+Pantoprazole consists of pantoprazole and levosulpiride as active ingredients. Based on the cause and your medical history, your doctor shall prescribe one of these medicines. Take the prescribed medicine only. Do not self-medicate.

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