Lercanidipine

Q: What are the lifestyle changes that should be adopted by a patient with high blood pressure?

Low salt intake diet , Daily Regular exercise and walking , Use of sunflower or safflower cooking oil , Decrease body weight according to height

Molecule Description

Lercanidipine is ‘calcium channel blocker’ medicine that lowers high blood pres

sure (hypertension).

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Lercanidipine

High blood pressure.

Contraindications of Lercanidipine

When should one not use Lercanidipine

Do not take this medicine if:
You are allergic to this medicine or other calcium channel blocker medicines
You have heart failure
You have severe kidney disease
You have severe liver disease
You have unstable angina
You are pregnant
You are breastfeeding
You are taking Ciclosporin, antifungal medicine, Macrolide antibiotics, antiviral medicine

Side effects of Lercanidipine

Common side effects of this drug are:

Angina
Chest pain
Decrease in blood pressure
Allergic reaction

Precautions and Warnings of Lercanidipine

Pregnancy

Can I take Lercanidipine during pregnancy?

This medicine should not be taken in pregnancy as it can harm an unborn baby. Consult with the doctor before taking medicine.

Breast Feeding

Can I take Lercanidipine while breastfeeding?

No data available whether this medicine passes in breast milk or not. Therefore avoid this medicine during breastfeeding. Consult with the doctor before taking medicine.

Driving

Can I drive if I have consumed Lercanidipine?

It may impair the ability to drive. You may feel dizziness, drowsiness.

Alcohol

Can I consume alcohol with Lercanidipine?

Patients should not consume alcohol while taking this medicine as it can cause dizziness, tiredness as it further decreases the blood pressure.

Other General Warnings

Talk to your doctor if

You have heart disease called sick sinus syndrome or angina
You have liver disease
You are on dialysis for kidney disease

Mode of Action of Lercanidipine

How Does It Work?

Lercanidipine blocks L-type calcium channels in the smooth muscle cells of blood vessels, relaxing them, and thus lowering blood pressure.

Interactions of Lercanidipine

Interactions with other medicines

Antacids like Cimetidine and Ranitidine
Itraconazole
ketoconazole
Erythromycin
Phenytoin
Ritonavir
Simvastatin
Carbamazepine
Rifampicin
Beta-blockers like Metoprolol
Diuretics
Digoxin

Interactions with food items

The medicine should be taken at least 15 minutes before breakfast, as a diet rich in fat increases medicine level in the blood
Grapefruit or its juice increases the effect of medicine
The patient should reduce salt intake, eat more potassium-rich foods, avoid caffeine

Dietary Restrictions of Lercanidipine

No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for further information.

Dosage of Lercanidipine

Overdose

The effect of an overdose may be harmful as it may further lower your blood pressure that may lead to unconsciousness and you may require immediate medical attention.

Missed a Dose

If you missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dos...

Content Details

WRITTEN BY

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking Lercanidipine?

Inform the doctor about your detailed medical and surgical history
Inform your physician if you have any of the following conditions:
Liver disease
Heart disorder
Kidney disease
If you are pregnant, lactating or planning a pregnancy

Q: What are the lifestyle changes that should be adopted by a patient with high blood pressure?

Low salt intake diet
Daily Regular exercise and walking
Use of sunflower or safflower cooking oil
Decrease body weight according to height

References

EMA. PIL. Lercanidipine. [Accessed on 3. Feb. 2020] (online)

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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