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Kanamycin

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Molecule Description

Kanamycin is an aminoglycoside antibiotic that is used to treat severe bacterial infections and tuberculosis.

Uses

This medicine is prescribed to treat severe bacterial infections, including tuberculosis.

Contraindications

When should one not use Kanamycin

  • Do not take this medicine if:
  • You are allergic to this medicine and any of its components
  • You have Parkinson's symptoms
  • You have myasthenia gravis
  • You have kidney disease
  • You have a sensation of spinning or whirling
  • You are pregnant

Side effects

Common side effects of this drug are:

  • Pain or irritation at the injection site
  • Mild skin rash
  • Headache
  • Fever
  • Nausea or vomiting
  • Spinning sensation
  • Ringing or roaring sound in your ears
  • Numbness or tingling of your skin
  • Fits (seizures or convulsions)

Precautions and Warnings

Pregnancy

Pregnancy

It is unsafe to use during pregnancy as it may cause adverse effects on unborn babies. The patient should consult with the doctor.

Breast Feeding

Breast Feeding

It is probably safe to use during nursing as this medicine passes in breast milk in tiny amounts and do not cause any adverse effects on breastfed baby.

Driving

Driving

You may feel dizzy, sleepy, tired or experience decreased alertness. Be cautious while driving.

Alcohol

Alcohol

Interaction with alcohol is unknown.

Other General Warnings

Other General Warnings

Talk to your doctor if
You have severe kidney disease.

Mode of Action

How Does It Work?

This medicine works by binding to certain cell subunits of bacteria, causing misreading of t-RNA. This leads to non-synthesis of protein require to bacterial growth.

Interactions

Interactions with other medicines

  • Selected Nephrotoxic agents/ Cidofovir
  • Aminoglycosides/ Ataluren
  • Antimicrobials/ live typhoid vaccine
  • Misc antibiotics/ neuromuscular blocking agents
  • Selected Nephrotoxic agents/ Foscarnet
  • Selected Nephrotoxic agents/ Inotersen
  • Selected Antimycobacterials/ live BCG
  • Aminoglycosides/ anesthetics

Interactions with food items

No specific food interactions are reported.

Dosage

Overdose

Overdose symptoms may include ringing in ears, hearing problems, dizziness, problems with balance or fits.

Missed a Dose

If you missed a dose, follow the regular dosing schedule. Do not double the dose.

Frequently Asked Questions (FAQs)

Give a detailed account of your medical and surgical history. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.

This medicine is useful in multidrug-resistant tuberculosis patient where medications which are routinely used for the treatment of tuberculosis are not working.

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