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Insulin Glulisine

Molecule Description

Insulin Glulisine is short and rapidly-acting insulin which is used to lower the...
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    Side effects
    Precautions and Warnings
    Mode of Action

Uses of Insulin Glulisine

It is used to treat Type 1 diabetes (in adults and children).

Contraindications of Insulin Glulisine

When should one not use Insulin Glulisine

  • If you are allergic to this medicine or any other ingredients of this medicine
  • If your blood sugar is too low (hypoglycaemia)

Side effects of Insulin Glulisine

Common side effects of this drug are:

  • Low blood sugar level (hypoglycaemia)
  • Sweating
  • Shaking of hands
  • Anxiety
  • Fast heartbeat
  • Severe swelling of skin or mucous membranes (angioedema)
  • Shortness of breath, a fall in blood pressure with rapid heart beat and sweating
  • Blurred vision
  • Skin and allergic reactions at the injection site

Precautions and Warnings of Insulin Glulisine



Can I take Insulin Glulisine during pregnancy?
Insulin Glulisine is not contraindicated in pregnancy but consult your doctor before you start the medication. Your doctor may change your dose of insulin in pregnancy and after childbirth.

Breast Feeding

Can I take Insulin Glulisine while breastfeeding?
Mothers with diabetes who need to take insulin can breastfeed their babies as suggested by their doctor.


Can I drive if I have consumed Insulin Glulisine?
Insulin is known to cause low blood sugar levels; these can lead to impairment in your driving ability. Always keep sugar or chocolate in your car with you while driving. In case you experience any of the symptoms of low blood glucose levels - stop driving and have some sugar.


Can I consume alcohol with Insulin Glulisine?
Consumption of alcohol may lead to an increased risk of both hypoglycemia (low blood glucose level) and hyperglycemia (high blood glucose level). Avoid excessive use of alcohol while taking insulin.

Other General Warnings

Talk to your doctor if
  • You have kidney or liver problem
  • You are ill or having major injuries
  • You have plans to travel abroad

Mode of Action of Insulin Glulisine

How Does It Work?

  • The primary activity of Insulin Glulisine is the regulation of glucose metabolism
  • Insulin allows the entry of blood glucose into each cell of the body
  • In Type 1 diabetes mellitus, the body fails to produce adequate insulin
  • This leads to glucose accumulating in the blood and causes high blood glucose level
  • Insulin Glulisine lowers blood sugar as it stimulates glucose uptake by cells, tissues and muscles and inhibits glucose production by the liver

Interactions of Insulin Glulisine

Interactions with other medicines

  • Medicines used to treat diabetes
  • Medicines used to treat certain heart conditions or high blood pressure
  • Medicines used to treat depression (Fluoxetine)
  • Medicines used to lower high levels of blood lipids (Fibrates)
  • Medicines used to treat high blood pressure
  • Medicine used to treat tuberculosis (Isoniazid)
  • Contraceptive pills used for birth control
  • Medicines used to treat psychiatric disorders (Phenothiazine derivatives)
  • Somatropin (growth hormone)
  • Medicines used to treat asthma (Salbutamol, Terbutaline)
  • Medicines used to treat HIV
  • Antipsychotic medicines (such as Olanzapine and Clozapine)

Interactions with food items

No information is available on interactions of Insulin Glulisine when taken with food, consult your doctor or pharmacist for further information.

Dosage of Insulin Glulisine


Overdose symptoms of Insulin Glulisine include low blood glucose, blurred vision, tingling and numbness in the tongue or mouth, fainting, seizures and coma. It can be life-threatening if not treated i...
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Missed a Dose

Take the next dose as soon as you remember; if the time for the next dose is close, skip the dose. Do not take double dose to compensate.

Content Details


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should I discuss with my healthcare expert before taking Insulin Glulisine?

A: Give a detailed account of your medical and surgical history. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.

Q: What special precautions should I follow?

A: Use Insulin Glulisine with caution in elderly persons. Monitor your blood sugar levels regularly. Be careful and alert about a sudden drop in blood sugar levels. Always keep sweets (chocolates, candy) for low sugar conditions.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)
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