Indometacin / Indomethacin

• Rheumatoid arthritis
• Osteoarthritis
• Ankylosing spondylitis
• Degenerative joint disease
• Gout and lumbago
• Pain after orthopaedic surgeries

When should one not use Indometacin / Indomethacin

• If you are allergic to indometacin / indomethacin or any other ingredient of this medicine.
• If you have experienced asthma, runny nose, swelling and rashes on your skin after using any painkiller.
• If you have ulcers or a history of frequent ulcers or bleeding in the stomach after using painkillers.
• If you have serious heart, kidney or liver-related disorder.
• If you have nasal polyps.
• If you are in the third trimester of pregnancy.

Common side effects of this drug are:

• Headache
• Dizziness
• Nausea
• Vomiting
• Stomach pain
• Diarrhoea
• Constipation
• Itching
• Rashes

Other General Warnings

• You are using other painkillers containing paracetamol.
• You have high blood pressure or related heart disorders.
• You have kidney and blood-related issues.
• You have an existing infection or asthma.
• You are using this medicine for a prolonged period.
• You have any eye-related disorders or experience eye-related issues.
• You have Rheumatoid disease characterised by severe pain in the joints
• You are an elderly patient.
• You have ulcers in the digestive system.
• You have systemic lupus erythematosus characterised by severe weakness.

How Does It Work?

Interactions with other medicines

• Concomitant use of other painkillers, such as aspirin with Indometacin / Indomethacin, can increase the risk of side effects.
• The effect of Indometacin / Indomethacin can be reduced when used with antacids.
• If taken along with warfarin, the effect of warfarin and the risk of bleeding may be increased.
• Medicines used for brain disorders, such as Fluoxetine and Citalopram, can increase the risk of bleeding with Indometacin / Indomethacin.
• Blood glucose lowering action of anti-diabetics like Glimepiride, and Glyburide is increased if taken along with Indometacin / Indomethacin.
• Antiplatelet medicines like Aspirin, Clopidogrel if taken along with this medicine can increase the risk of bleeding in the stomach and intestine.
• Digoxin, a medicine used to treat heart failure, when used together with this medicine can worsen the condition of the heart.
• Steroidal medicines like corticosteroids such as Betamethasone and Prednisone increase the risk of bleeding and ulcer formation when taken together with this medicine.
• Medicine used for High blood pressure, like Enalapril, Quinapril, Losartan and Telmisartan, when used together with this medicine, can increase the risk of kidney failure.
• Mifepristone should not be used with this medicine as the effect of mifepristone may be decreased.
• Antibiotics like ciprofloxacin, and levofloxacin can increase the risk of fits when used together with Indometacin / Indomethacin.
• Tacrolimus, a medicine given after transplantation surgeries to prevent organ rejections, when given with this medicine can increase the risk of kidney-related issues.
• Other medicines, such as certain antibiotics, antivirals, antigout, medicines used for related brain disorders, muscle relaxants, anticancer drugs, and immunomodulators, may interfere with the action of Indometacin / Indomethacin or increase the risk of toxicity or some complications. Discuss with your doctor if you are taking any other medicines.

Interactions with food items

Overdose

Missed a Dose