molecule

Indapamide

Molecule Description

Indapamide is a ‘Diuretic’ medicine used to lower the high blood pressure level.

Uses of Indapamide

It is used in the treatment of high blood pressure.

Contraindications of Indapamide

When should one not use Indapamide

  • If you are allergic to this medicine or any other Sulfonamide medicine
  • If you have severe kidney or liver disease
  • If you have low blood potassium level

Side effects of Indapamide

Common side effects of this drug are:

  • Low blood potassium level leading to muscle weakness
  • Skin rash
  • Swelling of face, lips or tongue, throat which causes difficulty in breathing
  • Swelling around the eyes, hands or feet
  • Skin reactions including intense skin rash, redness of skin, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes
  • Irregular heartbeat
  • Inflammation in pancreas and liver

Precautions and Warnings of Indapamide

Pregnancy

Q:
Can I take Indapamide during pregnancy?
A:
This medicine should not be taken if you are pregnant as it may harm unborn babies. Consult your doctor for advice.

Breast Feeding

Q:
Can I take Indapamide while breastfeeding?
A:
This medicine passes in breast milk and can cause adverse effects in breastfed babies. Therefore avoid breastfeeding when you are taking this medicine.

Driving

Q:
Can I drive if I have consumed Indapamide?
A:
It may cause dizziness and weakness, therefore avoid driving.

Alcohol

Q:
Can I consume alcohol with Indapamide?
A:
It is unsafe to consume alcohol with this medicine. It may have additive effects in lowering your blood pressure.

Other General Warnings

Talk to your doctor if
  • You have heart disease, liver disease, kidney disease, increased serum uric acid level
  • You have gout (painful joints due to increased blood uric acid level)
  • You have diabetes
  • You are sensitive to sunlight exposure

Mode of Action of Indapamide

How Does It Work?

This medicine is used to treat high blood pressure and works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.

Interactions of Indapamide

Interactions with other medicines

  • Medicines used in the treatment of ulcers
  • Diuretics or water tablets like Bumetanide, Furosemide, Amiloride, Spironolactone
  • Medicines to treat irregular heartbeat like Lidocaine, Flecainide
  • Intravenous Erythromycin, an antibiotic
  • Medicines used in the treatment of protozoal infections like Pentamidine
  • Medicines used to treat high blood pressure like Prazosin
  • Medicines for fits or epilepsy such as Oxcarbazepine
  • Medicines used to treat mental disorders
  • Muscle relaxant (to treat muscle stiffness occurring in disease such as multiple sclerosis) like Baclofen
  • Medicines treat high blood pressure
  • Medicines used in the management of arthritis (Non- Steroidal Anti Inflammatory Drugs) such as Aspirin and Ibuprofen
  • Medicines used to treat fungal infections like Amphotericin B
  • Calcium tablets or other calcium supplements

Interactions with food items

The patient should not eat or drink grapefruit or its juice along with this medicine as it can increase the side effects of this medicine.
dietaryRestrictions

Dietary Restrictions of Indapamide

No data available.

Dosage of Indapamide

Overdose

Overdose symptoms may include nausea, weakness, giddiness, dry mouth, thirst and muscle pain or weakness. Consult your doctor if you have any side effects.

Missed a Dose

Take medicine as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and go back to the regular dosing schedule. Do not take a double dose.

Content Details

WRITTEN BY
doctor

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: What should I discuss with my healthcare expert before taking this medicine?

A: You should not use this medicine if you are allergic to it or to sulfa medicines, or if you are unable to urinate. Tell your doctor if you have liver disease, kidney disease, gout, diabetes, low levels of potassium or sodium in the blood and if you are on a low salt diet.

Q: What athletes should know before taking this medicine?

A: This medicine gives false-positive reaction in doping test, athletes should be aware of it.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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