Imeglimin Hydrochloride
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Molecule Summary
| Uses | Type 2 diabetes |
| Therapy | Anti-Diabetic |
| Side Effects | Nausea, Diarrhea and Constipation. |
Medicines
available
19k pincodes
Molecule Description
Imeglimin Hydrochloride is a medication used to treat type 2 diabetes. It aids the pancreas in producing more insulin, enhances pancreatic function, and safeguards human cells from deterioration. It boosts insulin secretion and sensitivity while reducing peripheral insulin resistance.
Side effects of Imeglimin Hydrochloride include nausea, diarrhea, constipation, weakness, feeling hungry and sweating. Imeglimin Hydrochloride is to be taken orally. Swallow the medicine with plenty of water; do not chew or crush it.
Uses
Imeglimin Hydrochloride is prescribed for managing type 2 diabetes mellitus. It should be used alongside a healthy diet and regular exercise to control blood sugar levels, thereby helping to prevent serious complications of diabetes, such as kidney damage and blindness.
Contraindications
When should one not use Imeglimin Hydrochloride
- If you are allergic to Imeglimin Hydrochloride or any of its components.
- If you have high levels of ketones in your body (ketosis), are in a serious health crisis like a diabetic coma or near it, are about to have surgery, or are hurt.
- If you have type 1 diabetes or infections
- If you are pregnant or breastfeeding.
Side effects
Common side effects of this drug are:
- Nausea
- Diarrhea
- Constipation
- Weakness
- Feeling hungry
- Sweating
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any allergic reactions after taking Imeglimin Hydrochloride.
- You have any pre-existing medical conditions such as heart disorder, liver or kidney problem, thyroid, etc.
- You are getting suicidal thoughts after taking Imeglimin Hydrochloride.
- You are experiencing vision problems or dizziness and sleepiness.
- You are taking any other medicines (some medicines may interact, either enhancing or diminishing their effects, so be cautious with over-the-counter medicines, dietary supplements, and other prescription medications).
Mode of Action
How Does It Work?
Imeglimin Hydrochloride helps control blood sugar levels in people with type 2 diabetes. It works by improving how the body uses insulin and reducing the amount of sugar the liver produces. It also helps the muscles absorb more sugar from the blood, lowering overall blood sugar levels. This makes it easier for the body to manage glucose and reduces the risk of diabetes-related complications.
Interactions
Interactions with other medicines
- Some medicines can affect the way Imeglimin Hydrochloride functions, or Imeglimin Hydrochloride itself can diminish the effectiveness of other medicines taken concurrently.
- Inform your doctor about all the medicines, supplements, or herbal products you are currently taking or may take to avoid any potential interactions.
- If you are taking medicines that lower blood sugar levels, this could lead to additive effects with Imeglimin Hydrochloride. Always keep something sweet on hand to manage such situations, and monitor your blood sugar levels regularly.
Dosage
Overdose
Imeglimin Hydrochloride can reduce blood sugar levels without the need for glucose, particularly when taken in very high doses. This presents a risk in the event of an overdose, which could result in dangerously low blood sugar levels if not administered correctly. This is especially crucial for you if you have kidney or liver issues or if you are more sensitive to how Imeglimin Hydrochloride impacts your body. Seek immediate advice from your doctor in such cases.
Missed a Dose
If you have missed a dose of Imeglimin Hydrochloride, take it as soon as you remember. If it is time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of the medicine to make up for the missed one.
Frequently Asked Questions (FAQs)
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References:
- PubChem. Imeglimin Hydrochloride [Internet]. Nih.gov. PubChem; 2025 [cited 13 Jun 2026].
- Clémence C, Fouqueray P, Sébastien B. In Vitro Investigation, Pharmacokinetics, and Disposition of Imeglimin, a Novel Oral Antidiabetic Drug, in Preclinical Species and Humans. Drug Metabolism and Disposition. 2020 Oct 5;48(12):1330–46. [cited 13 Jun 2026].
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