Flutamide

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Molecule Description

Flutamide is anti-androgenic medicine which blocks testosterone (male sex hormone) action in the body.

Uses

It is used in the treatment of prostate cancer
It is also used after surgical removal of testis (castration)

Contraindications

When should one not use Flutamide

If you are allergic to Flutamide.

Side effects

Common side effects of this drug are:

Yellow discolouration of skin, nails, eyes
Clay coloured stools
Dark urine
Upper stomach pain
loss of appetite
Itching over the skin
Nausea and vomiting
Breathing difficulty
Tenderness or mild breast swelling
Swelling over face or lips
Tiredness
Sleepiness
Loose motions

Precautions and Warnings

Pregnancy

This medicine is used only to treat male medical condition. Hence not prescribed to women.

Breast Feeding

This medicine is used only to treat male medical condition. Hence it is not prescribed to women.

Driving

It causes tiredness, dizziness or confusion. You should avoid driving during this course of treatment.

Alcohol

You should not consume alcohol in large quantities while on treatment with this medicine.

Other General Warnings

Talk to your doctor if

You have heart disease, liver disease, kidney disease, brittle bone or breathlessness
You have diabetes

Mode of Action

How Does It Work?

Flutamide prevents the action of male sex hormones in the body, thereby decreasing the growth of prostate cancer.

Interactions

Interactions with other medicines

Blood thinners (Warfarin)
Theophylline (to treat breathing problem)
Medicines that can affect your liver or electrical activity of your heart
Medicines to treat cancers like Leuprorelin

Interactions with food items

No information is available on interactions of Flutamide when taken with food, consult your doctor or pharmacist for further information.

Dietary Restrictions

No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for further details.

Dosage

Overdose

Symptoms of this medicine's overdose include decreased activity, slow breathing, dizziness, watering eyes, upraised body hair, decreased appetite or vomiting. Consult with your doctor immediately.

Missed a Dose

If you miss a dose, do not take the double dose to catch up the skipped dose. Follow your regular dosing schedule.

Frequently Asked Questions (FAQs)

You must inform your doctor if you are allergic to FlutamideTell your doctor if you have liver diseaseIf you are G6PD enzyme deficientIf you suffer from Hemoglobin M diseaseIf you smokeInform your doctor if you are taking any other medicines

Flutamide can cause diarrhea. Hence avoid taking laxatives and dairy products while you are taking FlutamideCaregivers must maintain hygiene, wash hands thoroughly, wear gloves while cleaning up the body fluids, trash, linen and laundry.Flutamide can pass in body fluids (stool, urine and vomit). Soiled clothes and linen must be washed separately

Drink more fluids to prevent dehydration in case of diarrhoeaAvoid direct exposure to excessive sunlight and use sunscreen when outdoors as this medicine can make your skin sensitive to sunlight

Your doctor may ask you to have regular blood tests such as liver function tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine or stomach pain as this medicine can cause liver damage.

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